MATERIAL SAFETY DATA SHEET - NO. M10
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
2. COMPOSITION/INFORMATION ON INGREDIENTS
CHEMICAL COMPOSITION (Percent by Weight)
Hazard Communication regulations of the U.S. Occupational Safety and Health Administration apply to this product.
NOTE: As used in this Material Safety Data Sheet, the term “particulate” refers to dust, mist, fume, fragments, particles and/or powder.
3. HAZARD IDENTIFICATION
3.1 EMERGENCY OVERVIEW
Metallic product which poses little or no immediate hazard in solid form. See label in Section 16. If
the material is involved in a fire; pressure-demand self-contained breathing apparatus and
protective clothing must be worn by persons potentially exposed to the airborne particulate during
or after a fire.
MSDS No. M10
April 1, 2009
3.2 POTENTIAL HEALTH EFFECTS
Exposure to the elements listed in Section 2 by inhalation, ingestion, and skin contact can occur when melting,
casting, dross handling, pickling, chemical cleaning, heat treating, abrasive cutting, welding, grinding,
sanding, polishing, milling, crushing, or otherwise heating or abrading the surface of this material in a manner
which generates particulate.
Exposure may also occur during repair or maintenance activities on contaminated equipment such as: furnace
rebuilding, maintenance or repair of air cleaning equipment, structural renovation, welding, etc.
Particulate depositing on hands, gloves, and clothing, can be transferred to the breathing zone and inhaled
during normal hand to face motions such as rubbing of the nose or eyes, sneezing, coughing, etc. 3.2.1. Inhalation
Beryllium: The beryllium in this product is not known to cause acute health effects. Inhaling particulate
containing beryllium may cause a serious, chronic lung disease called Chronic Beryllium Disease (CBD) in
some individuals. See section 3.2.5 Chronic (long-term health effects). 3.2.2. Ingestion
Ingestion can occur from hand, clothing, food and drink contact with particulate during hand to mouth activities such as eating, drinking, smoking, nail biting, etc.
Beryllium: The health effect of ingestion of beryllium in the form found in this product is unknown. 3.2.3. Skin
Beryllium: Particulate that becomes lodged under the skin has the potential to induce sensitization and skin
lesions. 3.2.4. Eyes
Exposure may result from direct contact with airborne particulate or contact to the eye with contaminated
hands or clothing. Damage can result from irritation or mechanical injury to the eyes by particulate. 3.2.5. Chronic (long-term health effects)
Beryllium: Inhaling particulate containing beryllium may cause a serious, chronic lung disease called chronic
beryllium disease (CBD) in some individuals. Over time, lung disease can be fatal. Chronic beryllium disease
is a hypersensitivity or allergic condition in which the tissues of the lungs become inflamed. This
inflammation, sometimes with accompanying fibrosis (scarring), may restrict the exchange of oxygen between
the lungs and the bloodstream. Medical science suggests that CBD may be related to genetic factors. 3.2.6. Carcinogenic References
Beryllium: The International Agency for Research on Cancer (IARC) lists beryllium as a Group 1 – Known
Human Carcinogen. The National Toxicology Program (NTP) lists beryllium as known to be human
IARC lists beryllium as a known human carcinogen (Group 1) and notes that the work environment of workers
involved in refining, machining and producing beryllium metal was associated with an increased risk of lung
cancer, “the greater excess was in workers hired before 1950 when exposures to beryllium in the work place
were relatively uncontrolled and much higher than in subsequent decades”; and “the highest risk for lung
MSDS No. M10
April 1, 2009
cancer being observed among individuals diagnosed with acute beryllium-induced pneumonitis, who represent
a group that had the most intense exposure to beryllium.” IARC further noted that “Prior to 1950, exposure to
beryllium in working environments was usually very high, and concentrations exceeding 1 mg/m3 [1000
micrograms per cubic meter] were not unusual.” 3.2.7. Medical Conditions Aggravated by Exposure
Persons with impaired pulmonary function, airway diseases, or conditions such as asthma, emphysema,
chronic bronchitis, etc. may incur further impairment if particulate is inhaled. If prior damage or disease to the
neurologic (nervous), circulatory, hematologic (blood), or urinary (kidney) systems has occurred, proper
screening or examinations should be conducted on individuals who may be exposed to further risk where
handling and use of this material may cause exposure.
Beryllium: The effects of chronic beryllium disease on the lungs and heart are additive to the effects of other health conditions.
3.3 POTENTIAL ENVIRONMENTAL EFFECTS
4. FIRST AID MEASURES
4.1 FIRST AID PROCEDURES
Breathing difficulty caused by inhalation of particulate requires immediate removal to fresh
air. If breathing has stopped, perform artificial respiration and obtain medical help. INGESTION:
Induce vomiting immediately as directed by medical personnel. Never give anything by
mouth to an unconscious person. SKIN:
Thoroughly wash skin cuts or wounds to remove all particulate debris from the wound. Seek medical
attention for wounds that cannot be thoroughly cleansed. Treat skin cuts and wounds with standard first aid
practices such as cleansing, disinfecting and covering to prevent wound infection and contamination before
continuing work. Obtain medical help for persistent irritation. Material accidentally implanted or lodged
under the skin must be removed. EYES:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids
occasionally. Get medical attention immediately.
4.2 NOTE TO PHYSICIANS
Treatment of Chronic Beryllium Disease:
There is no known treatment which will cure chronic beryllium
disease. Prednisone or other corticosteroids are the most specific treatment currently available. They are
directed at suppressing the immunological reaction and can be effective in diminishing signs and symptoms of
chronic beryllium disease. In cases where steroid therapy has had only partial or minimal effectiveness, other
immunosuppressive agents, such as cyclophosphamide, cyclosporine, or methotrexate, have been used. These
latter agents remain investigational. Further, in view of the potential side effects of all the immunosuppressive
medications, including steroids such as prednisone, they should be used only under the direct care of a
physician. In general, these medications should be reserved for cases with significant symptoms and/or
significant loss of lung function. Other symptomatic treatment, such as oxygen, inhaled steroids or
bronchodilators, may be prescribed by some physicians and can be effective in selected cases.
The decision about when and with what medication to treat is a judgment situation for individual physicians.
For the most part, treatment is reserved for those persons with symptoms and measurable loss of lung function.
MSDS No. M10
April 1, 2009
The value of starting oral steroid treatment, before signs or symptoms are evident, remains a medically unresolved issue. The effects of continued low exposure to beryllium are unknown for individuals who are sensitized to beryllium or who have a diagnosis of chronic beryllium disease. It is generally recommended that persons who are sensitized to beryllium or who have CBD terminate their occupational exposure to beryllium.
5. FIRE FIGHTING MEASURES
Only in powder or other finely divided form does this material present a special fire problem. To extinguish a metal powder fire, use Class D fire extinguishing powder.
Do not use water to extinguish fires around operations involving molten
metal due to the potential for steam explosions. In addition, water may disassociate when in contact with burning metal particulate or chips releasing flammable hydrogen gas which could burn and result in an explosion. Ventilation duct work which has accumulated a fine coating of this material as a particulate on its internal surface poses a potentially serious fire hazard. Extinguish using Class D fire extinguisher media and shut down or isolate the affected portion of the ventilation system. Because of this potential risk, sources of ignition such as flame, spark from machining of other materials, welding spark, etc. must not be allowed to enter the ventilation duct work. Also, duct work must be made of non-combustible material. See Section 8 for further information regarding personal protective measures.
Pressure-demand self-contained breathing apparatus must be worn by firefighters or any other persons potentially exposed to the particulate released during or after a fire.
6. ACCIDENTAL RELEASE MEASURES
STEPS TO BE TAKEN IF MATERIAL IS RELEASED OR SPILLED
If this material is a particulate, establish a restricted entry zone based on the severity of the spill. Persons entering the restricted zone must wear adequate respiratory protection and protective clothing appropriate for the severity of the spill (see Section 8). Cleanup spills with a vacuum system utilizing a high efficiency particulate air (HEPA) filtration system followed by wet cleaning methods. Special precautions must be taken when changing filters on HEPA vacuum cleaners used to clean up hazardous materials. Be careful to minimize airborne generation of particulate and avoid contamination of air and water. Depending upon the quantity of material released into the environment, the incident may be required to be reported to the National Response Center at (800) 424-8802 as well as the State Emergency Response Commission and Local Emergency Planning Committee.
7. HANDLING AND STORAGE
Particulate may enter the body through cuts, abrasions or other wounds on the surface of the skin. Wear gloves when handling parts with loose surface particulate or sharp edges.
MSDS No. M10
April 1, 2009
8. EXPOSURE CONTROLS, PERSONAL PROTECTION
8.1 VENTILATION AND ENGINEERING CONTROLS
Whenever possible, the use of local exhaust ventilation or other engineering controls is the preferred method of controlling exposure to airborne particulate. Where utilized, exhaust inlets to the ventilation system must be positioned as close as possible to the source of airborne generation. Avoid disruption of the airflow in the area of a local exhaust inlet by equipment such as a man-cooling fan. Check ventilation equipment regularly to ensure it is functioning properly. Provide training on the use and operation of ventilation to all users. Use qualified professionals to design and install ventilation systems.
8.2 WORK PRACTICES
Develop work practices and procedures that prevent particulate from coming in contact with worker skin, hair, or personal clothing. If work practices and/or procedures are ineffective in controlling airborne exposure or visual particulate from deposition on skin, hair, or clothing, provide appropriate cleaning/washing facilities. Procedures should be written that clearly communicate the facility’s requirements for protective clothing and personal hygiene. These clothing and personal hygiene requirements help keep particulate from being spread to non-production areas or from being taken home by the worker. Never use compressed air to clean work clothing or other surfaces. Fabrication processes may leave a residue of particulate on the surface of parts, products or equipment that could result in employee exposure during subsequent material handling activities. As necessary, clean loose particulate from parts between processing steps. As a standard hygiene practice, wash hands before eating or smoking. To prevent exposure, remove surface scale or oxidation formed on cast or heat treated products in an adequately ventilated process prior to working the surface.
8.3 WET METHODS
Machining operations conducted under a flood of liquid coolant require complete hooded containment and local exhaust ventilation. Openings into the hood must be baffled to prevent release of fast moving particulate. The cycling through a machine of liquid lubricant/coolant containing finely divided beryllium particulate in suspension can result in the concentration building to a point where the particulate may become airborne during use. Prevent coolant from splashing onto floor areas, external structures or operators’ clothing. Utilize a coolant filtering system to remove particulate from the coolant.
8.4 RESPIRATORY PROTECTION
When airborne exposures exceed or have the potential to exceed the occupational limits shown in Section 8.15, approved respirators must be used as specified by an Industrial Hygienist or other qualified professional. Respirator users must be medically evaluated to determine if they are physically capable of wearing a respirator. Quantitative and/or qualitative fit testing and respirator training must be satisfactorily completed by all personnel prior to respirator use. Users of tight fitting respirators must be clean shaven on those areas of the face where the respirator seal contacts the face. Exposure to unknown concentrations of particulate requires the wearing of a pressure-demand airline respirator or pressure-demand self-contained breathing apparatus (SCBA). Use pressure-demand airline respirators when performing jobs with high potential exposures such as changing filters in a baghouse air cleaning device.
MSDS No. M10
April 1, 2009
8.5 OTHER PROTECTIVE EQUIPMENT
Protective overgarments or work clothing must be worn by persons who may become contaminated with particulate during activities such as machining, furnace rebuilding, air cleaning equipment filter changes, maintenance, furnace tending, etc. Contaminated work clothing and overgarments must be managed in a controlled manner to prevent secondary exposure to workers of third parties, to prevent the spread of particulate to other areas, and to prevent particulate from being taken home by workers.
8.6 PROTECTIVE GLOVES
Wear gloves to prevent contact with particulate or solutions. Wear gloves to prevent metal cuts and skin abrasions during handling.
8.7 EYE PROTECTION
Wear safety glasses, goggles, face shield, or welder’s helmet when risk of eye injury is present, particularly during melting, casting, machining, grinding, welding, powder handling, etc.
Use vacuum and wet cleaning methods for particulate removal from surfaces. Be certain to de-energize electrical systems, as necessary, before beginning wet cleaning. Use vacuum cleaners with high efficiency particulate air (HEPA). Do not use compressed air, brooms, or conventional vacuum cleaners to remove particulate from surfaces as this activity can result in elevated exposures to airborne particulate. Follow the manufacturer’s instructions when performing maintenance on HEPA filtered vacuums used to clean hazardous materials.
During repair or maintenance activities the potential exists for exposures to particulate in excess of the occupational standards. Under these circumstances, protecting workers can require the use of specific work practices or procedures involving the combined use of ventilation, wet and vacuum cleaning methods, respiratory protection, decontamination, special protective clothing, and when necessary, restricted work zones.
In accordance with OSHA regulation 29 CFR 1910.252 welding of materials containing beryllium is regulated as follows: Welding or cutting indoors, outdoors, or in confined spaces involving beryllium containing base or filler metals shall be done using local exhaust ventilation and pressure-demand airline respirators unless atmospheric tests under the most adverse conditions have established that the workers’ exposure is within the acceptable concentrations defined by 29 CFR 1910.1000. In all cases, workers in the immediate vicinity of the welding or cutting operations shall be protected as necessary by local exhaust ventilation or airline respirators.
8.11 CORROSION PROTECTION
Beryllium is corrosion-resistant in air and water up to 600°C. This is attributed to the formation of an adherent oxide layer on the surface. The presence of salts in water, particularly chloride, dramatically accelerates the corrosion of beryllium. This corrosion can be further accelerated (galvanic corrosion) if beryllium is in contact with a less reactive metal. Contrarily, beryllium can be protected from corrosion by contact with a more reactive metal (anodic protection).
MSDS No. M10
April 1, 2009
Generally, some corrosion protection should be applied to beryllium. Salts from handling beryllium without gloves along with humidity in the air are sufficient to cause “finger print” corrosion on a bare beryllium part. A chromate conversion coating is an effective protection for non-severe service. For applications where beryllium is exposed to salt spray or mist, an integral coating is needed to prevent corrosion. The conversion coating alone will not protect beryllium in salt spray applications. Conversion coating in combination with anodic protection with manganese or magnesium has been effective in protecting beryllium brake components on aircraft carrier based planes. Electroless nickel, epoxy paint and other integral coatings are effective corrosion barriers in salt spray applications.
8.12 EXPOSURE CHARACTERIZATION
Determine exposure to airborne particulate by air sampling in the employee breathing zone, work area, and department. Utilize an Industrial Hygienist or other qualified professional to specify the frequency and type of air sampling. Develop and utilize a sampling strategy which identifies the extent of exposure variation and provides statistical confidence in the results. Conduct an exposure risk assessment of processes to determine if conditions or situations exist which dictate the need for additional controls or improved work practices. Make air sample results available to employees.
8.13 MEDICAL SURVEILLANCE
Beryllium: Medical surveillance for beryllium health effects includes (1) skin examination, (2) respiratory history, (3) examination of the lungs, (4) lung function tests (FVC and FEV1), and (5) periodic chest x-ray. In addition, a specialized, specific, immunological blood test, the beryllium blood lymphocyte proliferation test (BLPT), is available to assist in the diagnosis of beryllium related reactions. Individuals who have an abnormal BLPT are normally referred to a lung specialist for additional specific tests to determine if chronic beryllium disease is present. Note: Substantial inter- and intra-laboratory disagreement exists among the laboratories that conduct this test. The BLPT does not at this time meet the criteria for a screening test. Despite its limitations, however, the BLPT remains a useful disease surveillance tool.
8.14 RISK FACTORS
Specific genetic factors have been identified and have been shown to increase an individual’s susceptibility to CBD. Medical testing is available to detect genetic factors in individuals.
8.15 OCCUPATIONAL EXPOSURE LIMITS
Brush Wellman recommends following good industrial hygiene practice which includes reducing airborne exposures to the lowest feasible level for all constituents in this product. Brush Wellman recommends that users of beryllium-containing materials maintain worker exposures to airborne beryllium to levels reliably below its recommended exposure guideline (REG) of 0.0002 milligrams beryllium per cubic meter of air.
*ALL CONCENTRATIONS ARE IN MILLIGRAMS PER CUBIC METER OF AIR (at the concentrations noted above, these constituents may not be visible to the human eye)
A leading scientific body recommending occupational standards is the American Conference of Governmental Industrial Hygienists (ACGIH). The ACGIH recommends standards for all listed substances. The ACGIH defines a threshold limit value (standard) as follows: “Threshold Limit Values refer to airborne concentrations of substances and represent conditions under which it is believed that nearly all workers may be repeatedly exposed day after day without adverse health effects. Because of wide variation in individual susceptibility,
MSDS No. M10
April 1, 2009
however, a small percentage of workers may experience discomfort from some substances at concentrations at or below the threshold limit; a smaller percentage may be affected more seriously by aggravation of a pre-existing condition or by development of an occupational illness.” “Individuals may also be hypersusceptible or otherwise unusually responsive to some industrial chemicals because of genetic factors, age, personal habits (smoking, alcohol, or other drugs), medication, or previous exposures. Such workers may not be adequately protected from adverse health effects from certain chemicals at concentrations at or below the threshold limits.”
American Conference of Governmental Industrial Hygienists
Occupational Safety and Health Administration
Eight-Hour Average Permissible Exposure Limit (OSHA)
Not To Be Exceeded Except for Peak Limit (OSHA)
30-Minute Maximum Duration Concentration Above Ceiling Limit (OSHA)
Eight-Hour Average Threshold Limit Value (ACGIH)
15-Minute Short Term Exposure Limit (ACGIH)
National Institute for Occupational Safety and Health
Registry of Toxic Effects of Chemical Substances
9. PHYSICAL AND CHEMICAL PROPERTIES
10. STABILITY AND REACTIVITY
Avoid contact with mineral acids and strong bases which generate
hydrogen gas. Hydrogen gas can be an explosion hazard.
11. TOXICOLOGICAL INFORMATION
For questions concerning toxicological information, write to: Medical Director, Brush Wellman Inc., 14710 West Portage River South Road, Elmore, Ohio 43416-9502.
12. ECOLOGICAL INFORMATION
This material can be recycled; contact your Sales Representative.
MSDS No. M10
April 1, 2009
13. DISPOSAL CONSIDERATIONS
13.1 BYPRODUCT RECYCLING
When recycled (used in a process to recover metals), this material is not classified as hazardous waste under federal law. Seal particulate or particulate containing materials inside two plastic bags, place in a DOT approved container, and label appropriately.
13.2 SOLID WASTE MANAGEMENT
When spent products are declared solid wastes (no longer recyclable), they must be labeled, managed and disposed of, in accordance with federal, state and local requirements. This material is not classified a hazardous waste under federal law. The U.S. Environmental Protection Agency has classified beryllium powder (P015) as a hazardous waste under the Resource Conservation and Recovery Act (RCRA). In Section 40 CFR 261.33(e) of RCRA, beryllium powder is considered hazardous when it is in the form of a “discarded commercial chemical product, off-specification species, container residue and spill residue, thereof.” This designation only applies to commercially pure products or manufacturing intermediates in which beryllium is the “sole active ingredient.” Due to the limited scope of this definition, we believe the only form of beryllium to which it applies is waste commercially pure metallic beryllium powder. Beryllium scrap, chips, and powder are normally recycled as by-products and are not classified a waste. In cases where this is not justified, seal any off-specification metallic beryllium powder in two plastic bags and then place in a DOT container approved for flammable solids. If being disposed, the outer container must be labeled with the appropriate EPA hazardous waste label and DOT hazard warning label(s) and shipped under a uniform hazardous waste manifest to an approved hazardous waste management facility. Dispose of dust collector filters contaminated with metallic beryllium powder following the above procedure, with the exception of the hazardous waste manifest and hazardous waste container label.
14. TRANSPORT INFORMATION
There are no U.S. Department of Transportation hazardous material regulations which apply to the packaging and labeling of this product as shipped by Brush Wellman.
Hazard Communication regulations of the U.S. Occupational Safety and Health Administration require this product be labeled.
15. REGULATORY INFORMATION
15.1 UNITED STATES FEDERAL REGULATIONS
15.1.1. Occupational Safety and Health Administration (OSHA)
Air contaminants, 29 CFR 1910.1000 Hazard Communication Standard, 29 CFR 1910.1200
15.1.2. Environmental Protection Agency (EPA)
AMBIENT AIR EMISSIONS:
Beryllium-containing materials are subject to the National Emission Standard
for Beryllium as promulgated by EPA (40 CFR 61, Subpart C). The National Emission Standard for beryllium
is 0.01 micrograms per cubic meter (30-day average) in ambient air for those production facilities which have
been qualified to be regulated through ambient air monitoring. Other facilities must meet a 10 gram per 24-
hour total site emission limit. Most process air emission sources will require an air permit from a local and/or
state air pollution control agency. The use of air cleaning equipment may be necessary to achieve the
MSDS No. M10
April 1, 2009
permissible emission. Tempered makeup air should be provided to prevent excessive negative pressure in a building. Direct recycling of cleaned process exhaust air is not recommended. Plant exhausts should be located so as not to re-enter the plant through makeup air or other inlets. Regular maintenance and inspection of air cleaning equipment and monitoring of operating parameters is recommended to ensure adequate efficiency is maintained.
Wastewater regulations can vary considerably. Contact your local and state governments
to determine their requirements.
TOXIC SUBSTANCES CONTROL ACT:
Component(s) of this material is/are listed on the TSCA
Chemical Substance Inventory of Existing Chemical Substances
SARA TITLE III REPORTING REQUIREMENTS:
On February 16, 1988, the U.S. Environmental
Protection Agency (EPA) issued a final rule that implements the requirements of the Superfund Amendments
and Reauthorization Act (SARA) Title III, Section 313 (53) Federal Register 4525. Title III is the portion of
SARA concerning emergency planning and community right-to-know issues. Section 313 covers annual
emission reporting on specific chemicals which are manufactured, processed or used at certain U.S. Industrial
This Brush Wellman product is reportable under the Section 313.
You may obtain additional information by calling the EPA SARA Title III Hotline at 1-800-535-0202 (or 703 412 9810).
15.2 STATE REGULATIONS
• Is listed on the following state right-to-know lists: California, New Jersey, Florida, Pennsylvania,
• The following statement is made in order to comply with the California State Drinking Water Act -
Warning: This product contains BERYLLIUM, a chemical known to the state of California to cause cancer.
• California No Significant Risk Level: CAS# 7440-41-7: No significant risk level = 0.1 μg/day
Ingredient Disclosure List
MSDS No. M10
April 1, 2009
16. OTHER INFORMATION
Following is the label which accompanies this product during shipment.
INHALING DUST OR FUMES MAY CAUSE CHRONIC BERYLLIUM DISEASE, A SERIOUS CHRONIC
LUNG DISEASE, IN SOME INDIVIDUALS. CANCER HAZARD. OVER TIME, LUNG DISEASE AND
CANCER CAN BE FATAL. TARGET ORGAN IS PRIMARILY THE LUNG.
READ THE MATERIAL SAFETY DATA SHEET (MSDS) ON FILE WITH YOUR EMPLOYER BEFORE
WORKING WITH THIS MATERIAL.
Overexposure to beryllium by inhalation may cause chronic beryllium disease, a serious chronic lung disease. • If processing or recycling produces airborne dust, fumes, or mists, use exhaust ventilation or other controls
designed to prevent exposure to workers. Examples of such activities include melting, machining, welding, grinding, abrasive sawing, sanding and polishing. Any activity which abrades the surface of this material can generate airborne dust.
• The Occupational Safety and Health Administration (OSHA) has set mandatory limits on occupational
• Beryllium metal, in solid form and as contained in finished products presents no special health risks.
• Sold for manufacturing purposes only. This product can be recycled; contact your sales representative.
The Occupational Safety and Health Administration requires employers to provide training in the proper use of this
For further information, please telephone or write to: Product Stewardship Department, Brush Wellman Inc., 6070
Parkland Boulevard, Mayfield Heights, Ohio 44124, telephone: (800) 862-4118, www.brushwellman.com. For
transportation emergency call Chemtrec at (800) 424-9300.
*Label color (light gray edge with black lettering)
This MSDS has been revised following the guidelines outlined in the American National Standard for Hazardous Industrial Chemicals -“Material Safety Data Sheets - Preparation.” Z400.1-1998
IMPORTANT: If you have any questions or require additional information regarding the materials
described in this Material Safety Data Sheet, please telephone or write to the Product Stewardship
Department at the location given on page 1. Additional product safety information, such as Safety
Additional information and guidance on the safe use and handling of these materials is available in the
“Interactive Guide to Working Safely with Beryllium and Beryllium-containing Materials.” This
innovative, computer based tool can be accessed online at www.berylliumsafety.com. A copy of the
Interactive Guide on compact disc (CD) can be obtained by contacting the Product Stewardship
Department at the location given on page 1.
!"#$%&'()*+,)-./,'01/)213)4*'3.1$0,1" !"#$ %#"&#'$ ('$ #"'#)$ *+),'"-*+$ #'./0'&%"*+#'$ 1()2#)3)('34'56$ 1"#-#$ 7)3)('34'5$ 3(''$ 2".$ 8#)-*+"#&#'#'$9#&"3(2#'.#'$ :#+('&#%.$ ;#)&#'$ <=,)>-,'?$9#-(%(/"'?$ 4'&$ 8"#%#$ 2#+)@6$ A4B5)4'&$ "+)#)$ 7)3)('34'5$ "-.$ &"#$C+#)(D"#$2".$A/
CLASSIFICATION ET MODE D'ACTION DES ANTIBIOTIQUES D.YALA*, A.S. MERAD** D. MOHAMEDI, M.N. OUAR KORICH***Un antibiotique est une substance antibactérienne d'origined'acide cl avulanique et qui agit sur les bactéries pro d u c -biologique, c'est à dire produite par des micro-organismes(champignons microscopiques et bactéries) ou de synthèsechimique et qui est cap able d'inhiber la mu