Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Microsoft word - cci pa list-12-07.doc

In an effort to promote the appropriate use of certain drugs and to help better manage the cost of expensive drugs, the ConnectiCare Pharmacy & Therapeutics Committee has developed a list of prescription drugs that require prior authorization. Prior authorization requests must be faxed to ConnectiCare’s Pharmacy Services department at 860-674-2851 or toll free 800-249-1367 by the prescribing physician’s office. POS members receiving out-of-network care are responsible for initiating this process. When submitting a request for Prior Authorization please use a Prior Authorization form which can be printed at ConnectiCare.com or obtained by calling ConnectiCare at 800-251-7722. If the prescribed drug is approved, the prescription will be filled as usual at a participating pharmacy or administered by a provider (where appropriate). Chantix (PA not required for initial 30 day supply) Aciphex (Use Prilosec OTC-Tier 1) Clarinex / D (Use loratadine OTC first-Tier 1) Contraceptives (if excluded by group) Allegra / Allegra D (Use loratadine OTC first-Tier 1) *Crestor (Use simva-, prava-, lovastatin first) Altoprev (Use simva-, prava-, lovastatin first) *Cymbalta (Use generic SSRI’s first) *Detrol / LA (Use oxybutynin IR/XL first) *Effexor XR (Use generic SSRI’s first) Aranesp (PA required for pharmacy claims only) *Enablex (Use oxybutynin IR/XL first) *Beconase AQ (Use generic flonase first) fexofenadine (Use loratadine OTC-Tier 1) *Cardura XL (Use generic doxazosin first) Fosamax plus D 5600 (Use fosamax plus D 2800) Note: Self administered medications (i.e. interferons), even those not on this list, may not be dispensed for self administration and
billed through the medical benefit by a provider, they must be dispensed through a participating pharmacy. (*) prior authorization is not
required within the first 90 days of membership with ConnectiCare.
(M) physician administered drug, usually billed under the medical benefit
Rev. 12/2007
In an effort to promote the appropriate use of certain drugs and to help better manage the cost of expensive drugs, the ConnectiCare Pharmacy & Therapeutics Committee has developed a list of prescription drugs that require prior authorization. Prior authorization requests must be faxed to ConnectiCare’s Pharmacy Services department at 860-674-2851 or toll free 800-249-1367 by the prescribing physician’s office. POS members receiving out-of-network care are responsible for initiating this process. When submitting a request for Prior Authorization please use a Prior Authorization form which can be printed at ConnectiCare.com or obtained by calling ConnectiCare at 800-251-7722. If the prescribed drug is approved, the prescription will be filled as usual at a participating pharmacy or administered by a provider (where appropriate). MMirena (levonorgestrel-releasing IUD) Myrac (Use generics first) *Nasacort AQ (Use fluticasone, Nasonex,or Veramyst first) *Nasarel (Use fluticasone,Nasonex,Veramyst first) Neulasta (PA required for pharmacy claims only) Injectable Drugs- All (excluding insulin) Klonopin Wafers (Use clonazepam tablets) *Omacor (note name change to “Lovaza”) *Omnaris (Use fluticasone, Nasonex, or Veramyst first) *Lescol/XL (Use simva-, prava-, lovastatin first) *Lipitor (Use simva-, prava-, lovastatin first) *Oxytrol (Use generic oxybutynin IR/XL first) Prevacid (Use Prilosec OTC-Tier 1) Minocin Combo Pack (Use generics first) Note: Self administered medications (i.e. interferons), even those not on this list, may not be dispensed for self administration and
billed through the medical benefit by a provider, they must be dispensed through a participating pharmacy. (*) prior authorization is not
required within the first 90 days of membership with ConnectiCare.
(M) physician administered drug, usually billed under the medical benefit
Rev. 12/2007
In an effort to promote the appropriate use of certain drugs and to help better manage the cost of expensive drugs, the ConnectiCare Pharmacy & Therapeutics Committee has developed a list of prescription drugs that require prior authorization. Prior authorization requests must be faxed to ConnectiCare’s Pharmacy Services department at 860-674-2851 or toll free 800-249-1367 by the prescribing physician’s office. POS members receiving out-of-network care are responsible for initiating this process. When submitting a request for Prior Authorization please use a Prior Authorization form which can be printed at ConnectiCare.com or obtained by calling ConnectiCare at 800-251-7722. If the prescribed drug is approved, the prescription will be filled as usual at a participating pharmacy or administered by a provider (where appropriate). MSynvisc (hyaluronate sodium) *Prozac Weekly (Use generics first) Travel Medication: including Malarone, *Rhinocort Aqua (Use fluticasone, Nasonex, Veramyst first) *Vesicare (Use oxybutynin IR/XL first) *Sanctura (Use oxybutynin IR/XL first) MVivaglobulin (SQ Immuneglobulin) Singulair (Use loratadine OTC first for allergic rhinitis) *Vytorin (Use simva-, prava-, lovastatin first) Weight Loss Medication (if covered by your plan); Meridia, Xenical, Ionamin, Tenuate, etc Xanax XR (use generic alprazolam) Steroids, Anabolic (i.e Nandrolone) Xyzal (Use OTC loratadine first-Tier 1) Zegerid (PA for age > 15 y/o) (Use Prilosec OTC) Note: Self administered medications (i.e. interferons), even those not on this list, may not be dispensed for self administration and
billed through the medical benefit by a provider, they must be dispensed through a participating pharmacy. (*) prior authorization is not
required within the first 90 days of membership with ConnectiCare.
(M) physician administered drug, usually billed under the medical benefit
Rev. 12/2007
In an effort to promote the appropriate use of certain drugs and to help better manage the cost of expensive drugs, the ConnectiCare Pharmacy & Therapeutics Committee has developed a list of prescription drugs that require prior authorization. Prior authorization requests must be faxed to ConnectiCare’s Pharmacy Services department at 860-674-2851 or toll free 800-249-1367 by the prescribing physician’s office. POS members receiving out-of-network care are responsible for initiating this process. When submitting a request for Prior Authorization please use a Prior Authorization form which can be printed at ConnectiCare.com or obtained by calling ConnectiCare at 800-251-7722. If the prescribed drug is approved, the prescription will be filled as usual at a participating pharmacy or administered by a provider (where appropriate). MZevelin
Zolinza
Zyban
Zyrtec / Zyrtec D (Use OTC)
Note: Self administered medications (i.e. interferons), even those not on this list, may not be dispensed for self administration and
billed through the medical benefit by a provider, they must be dispensed through a participating pharmacy. (*) prior authorization is not
required within the first 90 days of membership with ConnectiCare.
(M) physician administered drug, usually billed under the medical benefit
Rev. 12/2007

Source: http://www.cbia.com/ieb/ag/medical/zpdf/CtCare/CtCarePriorAuthorDrugList.pdf