Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Ml417700e

DAP Deutsches Akkreditierungssystem Prüfwesen GmbH
Annex to the Accreditation Certificate DAP-ML-4177.00
Accreditation based on DIN EN ISO 15189: 2003
Periode of validity: 2007-07-05 to 2012-07-04 MERKEZ ANALIZ ve SAGLIK HIZMETLERI TICARET
ve SANAYI LTD. STI
CENTRO LABORATUVARLAR I
Gürsel Mahallesi Kagithane Caddesi No. 14/3 clinical chemistry (including hematology,
hemostasology); immunology (immunology,
allergology); microbiology (including bacteriology,
infection serology, mycology, parasitology, virology,
molecular biology of infection serology); human
genetics; transfusion medicine (blood group)


1 Clinical
chemistry

1.1 Clinical
chemistry
SOP Parameter
Subgroup
Sample Type
Test Method
Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

1.2 Hematology

SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

1.3 Hemostaseology

SOP Parameter
Subgroup
Sample Type
Test Method
Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry 3576 Lupus Anticoagulant (LA) Hemostaseology Plasma (citrate) Coagulometry 3576 Protein C Activity Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry Hemostaseology Plasma (citrate) Coagulometry
2 Immunology

2.1 Immunology

SOP Parameter
Subgroup
Sample Type
Test Method
(EDTA/Heparin) Whole Blood (EDTA/Heparin), Immunoblot (IB) Indirect Immunofluorescence Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

Enzyme Linked
3695 Anti-Gliadin IgA Antibody Immunology Immunosorbent Assay (ELISA) Enzyme Linked 3696 Anti-Gliadin IgG Antibody Immunology Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Asp. (EDTA/Heparin), Body fluids Whole Blood Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
(Heparin) Whole Blood (EDTA/Heparin), bone marrow (EDTA/Heparin), fresh and paraffinized tissue, body fluids Immunoblot (IB) Indirect Immunofluorescence (Heparin) Whole Blood (EDTA/Heparin), Bone Marrow Asp. (EDTA/Heparin), Body fluids Whole Blood (EDTA/Heparin), Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Asp. (EDTA/Heparin), Body fluids Whole Blood (EDTA/Heparin), (EDTA/Heparin), Body fluids Whole Blood (EDTA/Heparin), Bone Marrow Asp. (EDTA/Heparin), Body fluids Whole Blood (EDTA/Heparin), Bone Marrow Asp. (EDTA/Heparin), Body fluids Whole Blood (EDTA/Heparin), Asp. (EDTA/Heparin), Body fluids Whole Blood (EDTA/Heparin), Bone Marrow Whole Blood (EDTA/Heparin), Bone Marrow Asp. (EDTA/Heparin), Body fluids, cryopreserved cell samples Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

2.2 Allergology

SOP Parameter
Subgroup
Sample Type
Test Method
4615 SpIgE e2 Dog Epithelium Allergology Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

Fluoroenzyme Immunoassay
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

Fluoroenzyme Immunoassay
4615 SpIgE fx3 Cereals/Flours Allergology 4615 SpIgE h1 Greer Labs.,Inc Allergology Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
4615 SpIgE w19 Wall Pellitory Allergology
3 Microbiology

3.1 Bacteriology

SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

3.2 Infection
serology
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method

Enzyme Linked
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00
SOP Parameter
Subgroup
Sample Type
Test Method
Molecular biology in infection diagnostics
SOP Parameter
Subgroup
Sample Type
Test Method

3.4 Mycology

SOP Parameter
Subgroup
Sample Type
Test Method
Periode of validity: 2007-07-05 to 2012-07-04 Annex to the Accreditation Certificate DAP-ML-4177.00

3.5 Parasitology

SOP Parameter
Subgroup
Sample Type
Test Method
Genetics
SOP Parameter
Subgroup
Sample Type
Test Method

5 Transfusion
medicine
SOP Parameter
Subgroup
Sample Type
Test Method

Abbreviations used:
of the Centro Laboratuvalari Merkez Analiz Periode of validity: 2007-07-05 to 2012-07-04

Source: http://centro.com.tr/download/Akredite%20test%20listesi.pdf

Hup1804.vp

HUMAN PERFORMANCE, 18 (4), 331–341Copyright © 2005, Lawrence Erlbaum Associates, Inc. The key to success in business is money and people. Personality psychology isabout people—it’s about the nature of human nature. Some understanding of hu-man nature—and the ability to measure its key components—would seem to offera huge advantage to applied psychologists. Despite its practical signif

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