Microsoft word - cattle fact sheet 15 - dermatomycoses.htm
Occupational Health - Zoonotic Disease Fact Sheets #15
[Ringworm (Dermatophytosis, Tinea, Trichophytosis, Microsporosis, Jock Itch, Athlete's
Dogs, cats, rodents, domestic animals
Organisms are subclassified into: 1. Geophilic - inhabit soil 2. Zoophilic -
parasitic on animals 3. Anthropophilic - Primarily infects humans. All can produce
disease in humans. Grouped in three genera 1. Microsporum 2. Trichophyton 3.
RESERVOIR AND INCIDENCE:
Fungal spores remain viable for long periods on
carrier animals and fomites. Exposure to reservoir hosts harboring different
dermatophytes determines the type and incidence of infection in humans. Microsporum
canis can be carried by up to 89% of nonsymptomatic cats. Up to 50% of people
exposed to infected cats, both symptomatic and asymptomatic, have acquired
Pets may also acquire disease from humans. **T. mentagrophytes is most
commonly transmitted to man from rodents, M. canis from dogs and cats, and T.
verrucosum from cattle and horses.
Direct or indirect contact with asymptomatic animals or with skin
lesions of infected animals Contaminated bedding Equipment Fungi in air, dust, or on
surfaces of room (spores persist on contaminated surfaces)
DISEASE IN ANIMALS:
Disease in rodents is often asymptomatic and not recognized
until people are affected. Infected cats are often asymptomatic. Dogs often show classic
skin lesions. Varying severity of dermatitis occurs with local loss of hair. Deeper
invasion produces a mild inflammatory reaction which increases in severity with the
development of hypersensitivity.
DISEASE IN MAN:
Often mild, self limiting; scaling, redness, and occasionally
vesicles or fissures. Thickening & discoloring of nails. May show circular lesions which
clear in the center forming a ring affect. Fungal infections in man are categorized as to
the location on the body: 1. Tinea capitis - Scalp & hair 2. Tinea corporis - Body
(extremities, arm and hand, are most often affected in infections acquired from lab
animals.) 3. Tinea pedis - foot 4. Tinea unguium - Nails
KOH mount of skin scrapings, Fungal culture
Macerated (moist softening and fissuring) stage- aluminum subacetate
("Domeboro") solution soaks with potassium permanganate for secondary infections.
Broad spectrum antifungal creams and solutions containing imidazoles or ciclopirox)
instead of tolnaftate and haloprogin help to combat diphtheroids and other gram-positive
organisms present at this stage and alone may be adequate therapy. Dry and scaly stage-
several topical creams, liquids, or lotions are recommended (miconazole, clotrimazole, ketoconazole, econazole, sulconazole, oxiconazole, ciclopirox or naftifine. Betamethasone dipropionate with clotrimazole is recommended for acutely inflamed tinea lesions. For severe cutaneous infections, griseofulvin or ketoconazole is recommended.
Screen newly received animals. Routine sanitization of
contaminated environment, equipment, and caging. Gloves, protective clothing, wash
hands after exposure.
Review Article © Schattauer 2012 Molecular imaging of matrix metalloproteinases in atherosclerotic plaques Sébastien Lenglet1; Aurélien Thomas2; Pierre Chaurand2; Katia Galan1; François Mach1; Fabrizio Montecucco1 1Cardiology Division, Foundation for Medical Research, Department of Medical Specialties, University of Geneva, Geneva, Switzerland; 2Department of Chemistry, Montréa
Jean E.T. McLain, Ph.D. Associate Director, University of Arizona Water Resources Research Center (WRRC) Associate Research Scientist, WRRC and Dept. of Soil, Water and Environmental Science 350 N Campbell Avenue, Tucson, Arizona 85719 My current research is directed towards establishing the public health and environmental safety of reclaimed municipal wastewater, with the goal of extendin