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CURRICULUM VITAE
Alex Jovencio Pena Makalinao
ASSOCIATED SITES
California Hematology Oncology Medical Group
California Hematology Oncology Medical Group RESEARCH EXPERIENCE
 Phase II Trial in Patients with Advanced or Metastatic Non-Small Cell Lung Cancer.
 Double-Blind, Placebo-Controlled, prevention of Acute & Delayed Chemotherapy-Induced Emesis.
 Double-Blind, Placebo-Controlled, of acute and delayed Chemotherapy-Induced Emesis.
 A Randomized, double-blind, placebo controlled, multicenter evaluation for the efficacy and safety of SMS 201-
995 pa LAR given with 5-FU in the treatment of patients with Stage IV Pancreatic Cancer.
 Phase III randomized trial of 5-U/Leucovorin/Levamisole versus 5-FU continuous infusion/Levamisole as adjuvant therapy for high risk respectable colon cancer, intergroup.
 A Phase II trial of Taxol, with Carboplatin in patients with advanced head and neck cancer.
 Phase II study of chemotherapy with Bactrim, AZT, G-CSF inpatients with AIDS related lymphoma.
 Phase III Intergroup trial of adjuvant chemoradiation after gastric resection for adenocarcinoma.
 A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Examine the Safety, Tolerability, and Efficacy of MK-0869 for the Prevention of Chemo-Induced Nausea and Vomiting Associated with High-Dose Cisplatin.
 Phase III Trial in Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) Who Were Previously Treated with Chemotherapy.
 Phase III Study in Patients with Unresectable, Locally Recurrent or Metastatic Breast Cancer.
 Open Label Study of PROCRIT (Epoetin Alfa) In Women Undergoing Adjuvant Chemotherapy for Stage I, II, or EDUCATION
UNIVERSITY OF THE PHILIPPINES, COLLEGE OF MEDICINE
Manila, Philippines – Doctor of Medicine University of the East College of Arts and Sciences Manila, Philippines – Bachelor of Science EMPLOYMENT EXPERIENCE
Associate
California Hematology-Oncology Medical Group, Inglewood, CA Hematology/Oncology University of California, Irvine, Orange, CA Principal Investigator for SWOG, Southwestern Oncology Group University of California, Irvine, Orange, CA Post-Graduate Resident (Internal Medicine) State University of New York, Mercy Hospital of Buffalo Consortium Post-Graduate Internship (Internal Medicine) State University of New York, Mercy Hospital of Buffalo Consortium Post-Graduate Internship (Rotating), University of the Philippines Philippine General Hospital, Manila, Philippines Clinical Clerkship, University of the Philippines Philippine General Hospital, Manila, Philippines MEDICAL LICENSURE
Certificate of Philippine Medical Licensure for Physicians
Board of MedicineProfessional Regulation Commission Republic of the PhilippinesPassed EXAMS/CERTIFICATION
Board Certified, Internal Medicine
Foreign Medicine Graduate Examination in the Medical Science (FMGEMS)Certified of Philippine Medical Licensure for Physicians Board Certified OncologyBoard Certified Hematology HOSPITAL AFFILIATIONS
Centinela Hospital Medical Center
Torrance Memorial Medical Center
Little Company of Mary Medical Center
UC Irvine Medical Center
AWARDS & HONORS
Incentive Award Recipient for Bone Marrow Transplant Program
Department of Obstetrics and Gynecology, UP-PGH, Manila, Philippines Department of Pediatrics, UP-PGH, Manila, Philippines Department of Community Medicine, UP-Comprehensive Community Health ProgramBay, Laguna, Philippines Department of Psychiatry, UP-PGH, Manila, Philippines Department of Family Medicine, UP-PGH, Manila, Philippines University of the East College of Arts & Sciences, Manila, Philippines University of the East, College of the Arts & Sciences, Manila, Philippines PUBLIC ABSTRACTS
Nagourney RA, Evans SS, Makalinao AJ, Su YZ. Gemcitabine activity inprimary cultures of human cancer. Proc.
AACR 37:318, 1996.
1996 AACR Meeting, Washington, D.C.
Nagourney RA, Su YZ, Makalinao AJ, Carolla A, Evans SS. Preliminaryanalysis of betulinic acid in human cancer primary culture. Proc. AACR37:399, 19961996 AACR Meeting, Washington, D.C.
Nagourney RA, Makalinao AJ, Evans YZ, Su J. Laboratory directed therapy for relapsed and refractory acuteleukemia. Proc AACR 15:33,1995.
1995 ASCO Meeting, Philadelphia, PA.
RESEARCH PAPERS
“Use of Cholecystokinin Biliary Scanning in Acalculus Cholecystitis”
State University of New York, Mercy Hospital of Buffalo
“The Bronchodilating Effect Datura metal”UP-PGH, Received the Best Experiment Award.
“The Therapeutic Index of Datura metal”UP-PGH, Manila, Philippines “Herbal Medicine in the Rural Areas”UP-PGH, Manila, Philippines LECTURES
Factor VIII Inhibitor
COMMITTEES
UCI Utilization Management Committee
Clinical Advisory Committee, UCI Medical Center, Orange, California UCIMC/UCI Health Systems, Orange, California

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Chapter 20 Accutane: Focus on Psychiatric Toxicity and Suicide Donald H. Marks, M.D., Ph.D. and Tzarina Middlekoop, Ph.D. Synopsis 20.1 Introduction 20.2 Mechanism of Action 20.3 Metabolism 20.4 Adverse Effects of Accutane A. Hypervitaminosis A B. Psychiatric adverse events C. Pseudotumor cerebri 1. London Independent 2. The Star-Ledger 3. The Advocate 20.6 Accutane and Sui

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