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NSAIDs for Dog Arthritis User Guides Part 5
– Aspirin

Aspirin or acetylsalicylic acid (ASA) is an NSAID used often to relieve minor pains, reduce fever, and alleviate inflammation. Aspirin also has an antiplatelet effect, which prevents blood from clotting. Hence, low doses of apirin are administered to people who are at risk of heart attacks and strokes. Currently, aspirin is the most widely used NSAID in the world, with 40,000 tons of it consumed each year.
Aspirin, specifically buffered aspirin, is used to treat pain and inflammation related to dog arthritis. However aspirin is now rarely used for the purpose because of the many alternative medications that have fewer side effects. Nonetheless, if aspirin should be administered, it should be done under the direct supervision of a veterinarian.
How It Works
Aspirin acts by inhibiting COX enzymes.
Buying Aspirin
Aspirin is not approved by the FDA for veterinary medicine; nonetheless it is an accepted practice to use the drug on dogs. Aspirin is an over the counter drug, but this does not mean that dog owners can just purchase and medicate your dog with it. As mentioned, direct supervision from a vet is needed.
How It Is Prepared
Aspirin now comes in chewable roast beef and natural liver-flavored tablet. There is also a snap and chew treat variation of the drug, which is best used for large dogs. For aspirin that is beef or live-flavored it is important to store It in secure place where other animals and children will not be able to reach the drug.
The active ingredient of aspirin used in dogs is buffered aspirin, which makes it gentler on your dog’s gastro-intestinal system. Nonetheless, the proper dosage should still be strictly observed. For small dogs, the one hundred milligram tablet is recommended with a dosage of eight to twelve milligrams per pound of dog’s weight every twelve hours. For large dogs, the 325 milligram tablet with the same dosage.
Overdosage & Side Effects
Aspirin works just like any NSAID; thus, it carries the same side effects. Keep note of any of the following side effets: vomiting, diarrhea, loss of appetite, darkening of stool coler, change in behavior, or decrease or increase in drinking water. If these symptoms continue for more than three days, discontinue using aspirin and have your dog examined by your vet.
Drug Interactions
The following drugs should be discussed with your vet if being used at the same time as Aspirin: * Corticsoteroids or NSAIDs such as Rimadyl How to Use Aspirin Safely
Aspirin should never, or very cautiously be given, to the following dogs: * Do not use on dogs that are allergic to aspirin.
* Do not use on dogs that have bleeding problems such as von Willbrands’ disease.
* Do not use on dogs that have pre-existing gastro-intestinal problems.
* Do not used on dogs that are pregnant or lactating

Source: http://www.dogarthritisblog.info/wp-content/uploads/2011/01/NSAIDs_User_Guides_Part_5.pdf

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