stopping a course of medicine as this maycause side effects too.
This drug is used principally for epilepsy buthas been shown to be very effective for some
cases of the rare condition of paroxysmal
nurses and specialists on what you’re taking
including any over-the-counter remedies as
well as herbal and homeopathic remedies. This is to ensure you are not duplicating
This is a drug used mainly for epilepsy but
neuropathy (damage to nerves in arms andlegs). It has been tried in dystonia although
there are no clinical trials and the evidence isanecdotal and whether it is truly effective is
unknown. It can help where there is chronic
intended to replace the advice of a qualifiedmedical practitioner. The Society strongly
advises anyone viewing this material to seek
qualified medical advice on all mattersrelat
Taking these medicines requires patience and
persistence on the part of the patient, their
cause information contained here to become
// It is a fact that medications are more likely
to be successful in children and youngpeople where a significant proportion canimprove dramatically through talking the
// While medications are an option for adults,
they are less likely to be effective and sobotulinum toxin treatment is often the bestoption for adults with focal dystonias.
2nd Floor, 89 Albert Embankment, London SE1 7TP
Most of these medicines have side effects.
Registered Charity No: 1062595 and SC042127
// Talk to your GP or neurologist before
acetylcholine. It is especially helpful for
(which is why it is important that dosages
childhood-onset and the more severe cases
of dystonia. However, people with adult focal
dystonia do sometimes also respond to the
The symptoms of dystonia can be challenging
As muscle relaxants, Baclofen and Tizanidine
to manage and it can often take some time
To minimise the likelihood of side effects, the
to get the balance of medications right to
physician will increase the dosage slowly.
achieve benefits for a person with dystonia.
Benefits may not appear for many weeks on
marked benefit in a significant minority of
This leaflet is designed to provide a brief
a constant dose, so lengthy trials are more
guide to the principal drugs used to provide
likely to be productive. Side effects can
minority of adults with focal dystonia. While
children can often tolerate high dosages of
sleepiness. In higher doses they can also
Baclofen, its side effects are a limiting factor
cause urinary problems, especially in men,
and worsen certain types of glaucoma. Short-
lethargy, upset stomach, dizziness and dry
dystonia (DRD) can find a dramatic, sustained
been reported. Talk to your GP or neurologist
discontinued abruptly. Very occasionally,
about your other medicines or if you have
baclofen is given via a pump directly to the
small doses of levodopa. This condition is
problems. It is important there is no abrupt
spinal cord region (intrathecal baclofen).
found primarily in dystonia affecting children
withdrawal from anticholinergics as dystonia
or young adults. In these instances, a trial of
therapy by the physician. In cases of adult-
onset dystonia, a physician is much less likely
These medicines can help control tremor and
suppressing release of chemical messengers
dystonia in their family. Most people with
in the brain such as dopamine and serotonin.
dystonia can tolerate these drugs and ill
They are usually used for more severe cases
aminobutyric acid) a chemical which inhibits
of dystonia and can also cause sedation and
the transmission of nerve signals in the brain
occasionally depression. If you’re taking
so acting as muscle relaxants. Patients can
sometimes tolerate very large dosages if the
This medicine belongs to the anticholinergic
doses are increased slowly. A number of side-
taking the medicine and phone for medical
spasms and the tremor by blocking the effect
of a chemical messenger in the brain called
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Epilepsy in Resource Poor Generalised seizures with focal signs: secondary gener- Countries—Suggestion of an Adjusted alised seizures with a focal start or clear unilateral seizures Classification but without major brain damage. There may be devel-opmental delay, subtle signs of brain damage and/or fo-According to the WHO 50 million people suffer fromcal neurology. Causes are ofte