Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.
Fittings.it
PLASTIC LITHIUM CELL HOLDERS “1/2AA” • “CR2” • “2/3A” FEATURES APPLICATIONS • Snap-In PC contact holds in position for wave soldering • Computer memory, power transfer and back-up systems • Tin Nickel Plated contacts for excellent solderability and durability • Video and telecommunications power back-up requirements • Polarity clearly marked for orientation • Preprogrammed video and electronic games • Low Profile, space-saving • Microprocessor, microcomputers, minicomputers, notebook, laptop • Snap-on retainer cover (optional) retains battery securely to withstand
and handheld computer memory hold applications
shock and vibration. Helps protect against shorting. Tamper-proof. • Emergency power systems • Residential, industrial and commercial security and fire alarm systems .125 [3.2] DIA. SPECIFICATIONS Base: PBT, UL Rated 94V-0 .094 [2.39] .047 [1.19] Retainer Cover: PBT, UL Rated 94V-0 Contacts: .012 (.30) Stainless Steel, Tin Nickel Plate .062[1.57] DIA. Operating Temp Range: -60ºF to +290ºF (-50ºC to +145ºC) X .062 [1.57] L. LEG RS E BATTERY CROSS REFERENCE D Energizer: 544,CR2, Duracell: PX28L, CR2, Kodak: K28A & “1/2 AA”
KS28, CR2, Panasonic: CR14250, CR2, Sanyo: CR14250SE, L “CR2”
CR2, Saft: LCP3, Maxell: 4LR44, CR2 Duracell: DL2/3A, Kodak: K123L, Sanyo: CR173335SE, “2/3 A” Saft: 450SC & VR0450 HO RUGGED STEEL & ALUMINUM LITHIUM CELL HOLDERS Y • Sturdily constructed of quality materials • Contacts made from Brass, Nickel Plate • Ideal for punishing applications BATTERY CROSS REFERENCE R STEEL HOLDERS “1/2AA” Energizer: 544, Duracell: PX28L, Kodak: K28A & KS28, E .144 [3.66] DIA. .128 [3.25] DIA. Panasonic: CR14250, Sanyo: CR14250SE, Saft: LCP3, HOLE (2) PLS Maxell: 4LR44 T .625 [15.9] T 1.224 [31.1] .430 [10.9] BA .144 [3.7] DIA. HOLE .128 [3.3] DIA. HOLE (2) PLS .082 [2.1] DIA HOLE 1.156 [29.4] (2) PLS. P/N 2103 CAT. NO. 2103 CAT. NO.1103 UM ALUMINUM HOLDERS “2/3A” BATTERY CROSS REFERENCE Duracell: DL2/3A, Kodak: K123L, Sanyo: CR173335SE, Saft: 450SC & VR0450 .625 [15.9] HI 1.557 [39.5] 1.125 [28.6] .111 [2.8] HOLE TYP. IT 1.125 [28.6] L .118 [3.0] DIA HOLE (4) PLS. .082 [2.08] DIA HOLE (2) PLS. FOR P/N 131 ONLY 1.474 [37.4] REF. CAT. NO.131 CAT. NO.132 6 VOLT LITHIUM CELL HOLDERS 1.125 [28.58] 1.125 [28.6] .125 [3.18] DIA. .415 [10.54] .125 [3.2] DIA. .415 [10.5] POLARIZING POLARIZING 1.000 [19.05] 1.000 [19.1] .187 [4.75] TAB .205 [5.21] TAB .238 [6.1] • Polarizing Tab for proper orientation .648 [16.5] .836 [21.25] • Lightweight, ideal for rugged applications • DL223A or Equivalent Batteries .750 [19.1] SPECIFICATIONS .648 [16.46] .239 [6.06] Frame: Aluminum 2024-T3 Terminals: Brass, Tin Plate .075 [1.9] Spring Contacts: .025 (.64) Dia. Spring Steel, Nickel Plate CAT. NO. 224 CAT. NO. 223 Tel (718) 956-8900 • Fax (718) 956-9040 20 (800) 221-5510 • kec@keyelco.com 31-07 20th Road – Astoria, NY 11105-2017RoHS COMPLIANT ~ ISO 9001 CERTIFIED
Can Elimination of Epinephrine in Rhinoplasty Reduce the SideEffects: Introduction of a New TechniqueAbdoljalil Kalantar-Hormozi • Alireza Fadaee-Naeeni •Siavash Solaimanpour • Naser Mozaffari •Hamed Yazdanshenas • Shahrzad Bazargan-HejaziReceived: 6 September 2010 / Accepted: 24 January 2011Ó The Author(s) 2011. This article is published with open access at Springerlink.comWe aim
Newsletter: October 2012 Monthly Meeting 25th October 2012 Tricia welcomed the smallish meeting, possibly due to the uncertainty of the weather. She expressed the meeting’s sympathy for committee member Ivo Chunnet, whose wife had died suddenly. But said how glad she was to see Sylvia at the meeting after her recent major surgery. She said that the previous two weeks had been the most dev