Curriculum Vitae 1. Name in Full: Professor Sudha Mahajan Cowsik, FAMS 2.Date of Birth: 3.Present Designation and address: Professor, School of Life Sciences, Jawaharlal 4. Nationality: Indian 5.Citizenship: Indian 6. Qualifications: Academic career and professional attainments: Degree/ Diploma University/Institution Year BSc (Hons. Sch) Punjab University, Chandigarh, India 1969 MSc (Hons. Sch) Punjab University, Chandigarh, India, 1970 Post M.Sc. (Dip) Indian Institute of Technology, New Delhi, India 1971 Ph.D AIIMS, New Delhi, India 1976 Awards/Special attainments: Academic Positions Professor, School of Life Sciences, Jawaharlal Nehru University, New Delhi, Sep. 95 till date Associate Professor, School of Life Sciences, Jawaharlal Nehru University, New Delhi, May 85-Aug 95 Assistant Professor, Centre for Bio-Medical Engineering, IIT and AIIMS Delhi Jan79- April8 5 Pool Officer(CSIR), Centre for Bio-Medical Engineering, AIIMS Delhi, Jan 77- Dec 78 Consultancy /Visiting Professorship Faculty, U.S.-India Joint Research Training Program in Global Infectious Diseases Consortium between JNU and Seattle Biomedical Research Institute (SBRI), Seattle, USA, 2006-till date Consultant, Neuroscience Drug Abuse Research program, North Carolina Central University, Durham, NC, USA (2005-2006) Visiting faculty, Department of Biochemistry and Molecular Biophysics,Washington University, Saint Louis, USA, 2004-2006. Visiting faculty, Department of Physiology and Pharmacology, Saint Louis University, Saint Louis, USA (1995-1996) Homi Bhabha Fellow, Indian Institute of Science, Bangalore, Jan.96-Dec.98 JNC Fellow, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, Aug94-Dec95 Visiting Scientist, INSA-DFG Exchange Programme, Goethe University Franfurt, Germany with Prof. H. Ruterjans, Dec91-Dec92 Fulbright Scholar, US Department of Agriculture Plant Molecular Biology Lab,Beltsville, Maryland, USA with Dr. Autar K. Mattoo, Dec89-March90 Visiting Scientist, TWAS-Chinese Academy of Sciences, Changchun Institute of Physics, China, with Prof. Zhang Xinyi, May89-July89 High level fellowship exchange scientist, University of Louis Pasteur, Strasbourg, France with Prof. R. Cerf, May85-Aug85 Max Planck fellow, Max Plank Institute, Gottingen, Germany, with Prof. H. Kuhn, April84-July84 Visiting Scientist under INSA- JSPS Exchange Programme, National Cancer Research Institute, Tokyo, with Dr H Saito, Jan84-March84 Visiting Scientist, Albert Einstein College of Medicine, New York with Dr Gene Morril & Dr R.Gupta May, 83-July83
Academic Honours
Kshanika Oration Award, Indian council of Medical research, India 2010 Elected Fellow, National Academy of Medical Sciences, India 2010 Elected Member, National Academy of Sciences, India 2002 IUPAB travel award International Biophysics Congress, Buenos Aires 2002 IUPAB travel award International Biophysics Congress, Vancouver 1990 S.V. Talekar Memorial Award, AIIMS, Delhi 1981. National Merit Scholarship holder throughout academic career Editorial Boards Lead Guest Editor of special issue of International Journal of Peptides Member, Editorial Board Open Access Structural Biology Journal Member, Editorial Board International Journal of Biotechnology and Biochemistry Adhoc reviewer for Biochemistry, USA Adhoc reviewer for Journal of Physical Chemistry, USA Adhoc reviewer for Journal of Biomolecular Structure and Dynamics, USA Publications Book: Trends in Biomedical Engineering , Eds. S.K. Guha, Sneh Anand and Sudha Mahajan, pp. 357, CBME Publication, 1978. Peer Reviewed Publications: 65 Presentations at International Conferences: 53 Other relevant information Professional Societies 2012-present Indian Academy of Neurosciences 2012-present International Cannabinoid Research Society, USA 2001-present American Biophysical Society 1993-present Indian Biophysical Society 1993-present Magnetic Resonance Society of India 1991-present International Society of Quantum Biology International 2010
Member, Advisory Board Asian Biophysics Meeting, Delhi Jan.31-Feb.4, 2011
2007 Chair session: Albany 2007: Conversation 15, June 19-23, USA 2005 Member, Advisory Board International Conference on Magnetic Resonance in Biological System, Hyderabad, Jan.16-21 2005 Chair session, International Conference on Magnetic Resonance in Biological Systems, Hyderabad, Jan.16-21 National Member, Advisory panel, National Academy of Medical Sciences, 2012
Member, local Organizing Committee: 7th Asian Biophysics Association and Annual
Indian Biophysical society Symposium on Biophysics: Trends in Biomedical Research
Chair session: NMRS symposium on Magnetic resonance and Biomolecular Mimetics: Feb.2-5, 2009, Hyderabad
Chair session: NMRS symposium on Magnetic resonance and Biomolecular Mimetics: Feb.2-5, 2009, Hyderabad
Member, National Advisory Board: National Symposium on Biophysics: Trends in Biomedical Research New Delhi, February 13 – 15, 2007
Member, National Advisory Board International Workshop on Biomedical Magnetic Resonance, All India Institute for Medical Sciences New Delhi January 12-15, 2005
Member, National Advisory Board, National Symposium on Biophysics, IIT Roorkee Feb. 20- 25, 2003
Member of UGC curriculum development committee in Biophysics, 1995-1998
Member of UGC review committee in Biophysics, 1999-2000
Teaching Experience Physics for Life Sciences for M.Sc. Life Sciences students, 1985 till date at Jawaharlal Nehru University, Delhi.
Structural Biology and Molecular Biophysics course for M.Sc students 1979 till date at Jawaharlal Nehru University, Delhi.
Medical Physics and Biophysics course for post graduates of Nuclear Medicine department from 1979 - 1985 at All India Institute of Medical Sciences, Delhi.
Physics and Instrumentation in Anaesthesiolgy course for post graduates of
Anaesthesiology Department at All India Institute of Medical Sciences, Delhi, 1979 - 1985.
Medical Biophysics course for M.Sc students from1979 - 1985 at Indian Institute of Technology, Delhi.
Undergraduate Physics at Indian Institute of Technology, Delhi 1979 - 1985.
Grants Principal Investigator- Structural analysis of Cannabinoid Receptor Interacting Protein using Bioinformatics tools, Fluorescence, CD and NMR spectroscopy, Indian Council of Medical Research, Government of India, 2013-2016, Rs.25,00,000
Principal Investigator- Modulation of structural and molecular aspects of membrane linked functions by estrogen in aging rat brain, University Grants Commission, India, 2010-2013, Rs.9,00,000
Principal Investigator- Tachykinin peptides: Structure, Dynamics and Drug Design, Indian Council of Medical Research, Government of India, 2007-2010, Rs.800,000
Principal Investigator-Molecular dynamics and spectroscopic characterisation of cyanobacterial phycobiliproteins, Department of Biotechnology, Government of India,2004-2009. Rs. 16,00,000
Principal Investigator -Structure based drug design: Structural characterization of tachykinin -G protein coupled receptor complex, Department of Science and Technology, Government of India , 2003-2006, Rs. 15 ,00,000
Principal Investigator- Tachykinin neuropeptides, Neurokinin B and Eledoisin:A molecular modelling, NMR and other spectroscopic investigation, Council of Scientific and Industrial Research, Government of India, 2003-2006, Rs.8,00,000
Principal Investigator - The Role of Tachykinin Neuropeptides on Molecular and Biochemical Correlates in Aging Brain Functions, Excellence Programme, University Grants Commission,India,2002-2007, Rs. 15,00,000
Principal Investigator - Lipid induced Structure of Neuropeptide Gamma and its analogues-A molecular modeling, Molecular Dynamics and NMR spectroscopic investigation, University Grants Commission, India, 2002-2005, Rs.7,00,000
Principal Investigator - Structure and dynamics of tachykinins: NMR Spectroscopy and molecular dynamics simulations, BRNS, Department of Atomic Energy, 1997- 2001, Rs. 5,50,000
Principal Investigator - Receptor mediated Neuro immunomodulation - A molecular modelling, NMR and other spectroscopic investigation, Dept. of Biotechnology, 1992- 1996. Rs. 42,00,000
Principal Investigator - Study of Mechanism of action of Tricyclic antidepressants at a Molecular level, Indian Council of Medical Research, Government of India, 1985 - 1988, Rs. 3,00,000
Principal Investigator - Drug Membrane interaction - A theoretical, NMR and other spectroscopic study. Council of Scientific and Industrial Research, Government of India, 1988 – 1991, Rs.4,00,000
Co-investigator - Non-surgical male fertility control, sponsored by the Indian Council of Medical Research, Government of India, 1979 - 1981, Rs. 7,00,000
Co-investigator - Development of biomedical transducers, sponsored by Electronic Commission, Government of India, 1978-1980, Rs. 7,00,000
Co-investigator - Project Mass Health Care, INDO-UK collaboration project, 1978 – 1980, Rs.20,00,000 Graduate Students Anjum Ansari, M.Sc. Biophysics Project: Interaction of local anaesthetics with liposomes -a biophysical study, 1985 - 1987. Supervisor
Rashmi Chabbra, Ph.D Project Study of L-Alanine: Dioxovalerate transminase from rat erythroid and non-erythroid sources using biochemical and biophysical techniques, 1986 - 1992. Co-supervisor
P.S. Maruthisai, Ph.D. Project: Characterization of Light Harvesting Pigment complexes in Cyanobacteria at a Molecular level , 1986 - 1990.Supervisor
D.R. Shukla, Ph.D. Project: Drug-membrane interactions: Conformational Analysis of Tachykinins,1987 - 1991 .Supervisor
I.B. Jha, Ph.D Project: Phycobiliproteins in Cyanobacteria: Isolation, spectroscopic characterization and energy transfer mechanisms, 1987-1993. Supervisor
A.M .Lynn,Ph.D Project: Molecular Mechanisms of ReceptorSelection: A Stereodynamic Investigation, 1992 - 1997.Supervisor
Indu R.Chandrashekar, Ph. D project: Structural characterization of tachykinin receptor ligand interaction, 2001-2005.Supervisor
M. Anil Kumar, Ph.D project: The Role of Tachykinin Neuropeptides on Molecular and Biochemical Correlates in Aging Brain Functions, 2001-2006. Supervisor
Anjali Dike, Ph.D project: Peptide interactions with G-Protein Coupled receptors-A Stereodynamic investigation, 2002-2007, Supervisor
Gunjan Pandey, Ph.D project: Spectroscopic characterization of lectin-phycobiliprotein conjugates, 2007- 2012, Co-supervisor
Rashmi Jha, Ph.D project: Molecular and Biochemical correlates in aging rat brain: Effect of Amyloid Protein, 2009- 2013, Co Supervisor
Priyanka Mishra, Ph.D project: Structural and Molecular aspect of Tachykinin peptides in neurodegeneration, 2011- till date, Co Supervisor
Raghvendra Dubey, M.Phil project: Neuroprotective action of Tachykinin Peptide Eledoisin in aging rat brain, 2011-2012 Supervisor
Ranjeet Kumar, M.Sc. Project: Neuroprotective effects of 17 Beta Estradiol on aging rat brain .2012, Supervisor
Pareeta, Ph.D. project: Mutational studies in Als5 protein from Candida albicans, 2012-till date, Co Supervisor
Pratishtha, M.Phil. project: structural analysis of cannabinoid receptor interacting protein (CRIP1a), 2012-till date, Suprevisor
Major Administrative Responsibilities
Interim Dean, School of Life Sciences, Jawaharlal Nehru University, New Delhi, 2001- 2004 (intermittently) Warden, Godavari Hostel, Jawaharlal Nehru University, New Delhi, 1986-1989 Major Committee Assignments
2001-2003 Member, Biotechnology Board, JNU, Delhi
2001-2003 Member, Academic council, JNU, Delhi
1999-2000 Campus Development Committee, JNU, Delhi
1997-2003 Member, Admissions Committee, Graduate program in Life Sciences
1992-1994 Member, Academic council, JNU, Delhi
Special Service to the Profession/Community
Participated actively in Science outreach Programmes in JNU, Delhi Publications Book: 1 Total number of Peer Review Publications: 65 Publications in Proceedings: 53 Book: Trends in Biomedical Engineering,Eds. S.K. Guha, Sneh Anand and Sudha Mahajan, pp. 357, CBME Publication, 1978. Ph.D. Thesis: Submolecular Mechanisms in Drug Action - A Topographical Analysisof Tricyclic Antidepressants, All India Institute of Medical Sciences, New Delhi 1976. Publication in Peer reviewed International Journals in last five years
1. Anjali Dike and Sudha M Cowsik. ‘Molecular Recognition of Tachykinin Receptor Selective Agonists: Insights from Structural studies’. Mini Reviews in Medicinal Chemistry 2013 ( in press) (Impact factor 4.90)
2. Rashmi Jha, Abbas Ali Mahdi, Shivani Pandey, Najma Z Baquer, Sudha M
cowsik. ‘Neuroprotective effect of 17β Estradiol on Membrane Fluidity in Aging RatBrain’. Biophysical Journal, (104) 2, 2013
3. Rashmi Jha, A.A Mahdi, Shivani Pandey , Najma Z Baquer and Sudha M Cowsik
‘Effects of Tachykinin neuropeptide NKB and Aβ (25-35) on antioxidant enzymes in 17β estradiol treated ageing rats’Advances in Aging Research 2013( in press)
4. Rashmi Jha, A.A Mahdi, Shivani Pandey , Najma Z Baquer and Sudha M Cowsik
‘Neuroprotective Role of 17β estradiol with Tachykinin neuropeptide NKB and Aβ (25-35) in ageing female rat brain’Advances in Aging Research 2013( in press)
5. Anjali Dike, Gita Subbarao, Sudha M Cowsik. ‘Molecular modeling of NKB and Neurokinin-3 receptor complex’ J. Chemical information and Modeling 51: 2932-2938(2011). (Impact factor 4.675)
6. Pardeep Kumar, Asia Taha, R. K. Kale, Sudha M Cowsik and Najma Z. Baquer,
‘Physiological and biochemical effects of 17β estradiol in aging female rat brain’. Experimental Gerontology 46(7): 597-605(2011). (Impact factor 3.644)
7. Najma Z. Baquer, Pardeep Kumar, Asia Taha, R. K Kale, Sudha M Cowsik and P.
McLean, ‘Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetic tissues’ J. Biosciences (India) 36(2): 383-96 (2011). (Impact factor 1.65)
8. C.Rani Grace and Sudha M Cowsik .’Solutio conformation of non- mammalian tachykinin physalaemin in lipid micelles by NMR’. Peptide Science (Biopolymer), epub July14, 2010: 96(3): 252-259 (2011). (Impact factor 2.87)
9. Pardeep Kumar, R. K Kale, Sudha M. Cowsik and Najma Zaheer Baquer ‘Age associated alternations of antioxidant status, calcium homoestatis and glucose transporter in female rat brain: Neuroprotective role of estradiol ‘J. Neurochemistry 115: 53 (2010). (Impact factor 4.061)
10. Pardeep Kumar, R. K Kale, Sudha M. Cowsik and Najma Zaheer Baquer
Membrane linked ATPases, membrane fluidity and glucose transporters in brain of aging female ratsJ. Neurochemistry 113:16, 2010. (Impact factor 4.061)
11. Gunjan Pandey; Tasneem Fatma; Sudha M Cowsik; Sneha S. Komath. ‘Specific interaction of jacalin with phycocyanin, a fluorescent phycobiliprotein’.J. Photochem. Photobiol B, 97: 87-93 (2009). (Impact factor 2.81)
12. Najma Zaheer Baquer, Asia Taha, Pardeep Kumar, P. McLean, Sudha M Cowsik,
R. K Kale, R. Singh, Deepak Sharma. ‘A Metabolic and Functional Overview of Brain Aging Linked to Neurological Disorders’ Biogerentology 10(4):377-413 (2009). (Impact factor 3.339)
Indu Chandrashekar, Gita Subbarao, Sudha M Cowsik. ‘Molecular modeling of the peptide agonist-binding site in Neurokinin-2 receptor’ J. Chemical information and Modeling 49(7): 1734-1740 (2009). (Impact factor 4.675)
14. Anjali Dike and Sudha M Cowsik. ‘Solution structure of NK1 agonist Phyllomedusin bound to DPC micelles’ Journal of Structural biology. 167(2): 176-184 (2009). (Impact factor 3.805)
15. Anjali Dike and Sudha M Cowsik. ‘Structural characterization of Neurokinin 3 receptor selective agonist Scyliorhinin II bound to DPC micelles’. J. Biomol. Struct.Dynamics 25(4): 395-406 (2008). (Impact factor 4.99)
16. C.Rani Grace, Sudha M. Cowsik, J. Y. Shim,Allyn C. Howlett and W.J. Welsh‘Conformational Characterization of a peptide mimetic of the fourth cytoplasmic loop of the G-protein coupled cannabinoid receptor.Journal of Structural biology 159(3): 359-368 (2007). PDBID: 2BOY (Impact factor 3.805)
17. . Anjali Dike, Indu R. Chandrashekar, Anil K. Mantha, Najma Z. Baquer and
Sudha M. Cowsik.‘Pharmacophore pattern identification of Tachykinin Receptor Selective Peptide Agonists: Implications in receptor selectivity’ Am.J. Biochem and Mol. Biol. 3(4): 180 – 186(2007) (Impact factor 3.777)
18. Anjali Dike and Sudha M Cowsik. ‘Solution structure of Amphibian tachykinin Uperolein bound to DPC micelles’. Journal of Structural biology 156(3):442- 452 (2006).PDBID: 2GFR (Impact factor 3.805)
19. Anjali Dike and Sudha M Cowsik. ‘Three dimensional structure of Neuropeptide K bound to dodecylphosphocholine micelles’. Biochemistry45 (9): 2994 -3004 (2006). PDBID: 2B19 (Impact factor 3.422)
20. Anil K. Mantha, K. Moorthy, Sudha M. Cowsik and Najma Z. Baquer.
‘Neuroprotective role of neurokinin B (NKB) on β - amyloid (25-35) induced toxicity in aging rat brain synaptosomes: Involvement in oxidative stress and excitotoxicity’. Biogerentology. 7:1-17(2006). (Impact factor 3.339)
21. Anil K. Mantha, K. Moorthy, Sudha M. Cowsik and Najma Z. Baquer ‘Membrane associated functions of neurokinin B (NKB) on Aβ (25-35) induced toxicity in aging rat brain synaptosomes’. Biogerentology. 7:19-33 (2006). (Impact factor 3.339)
22. K. Moorthy, Umesh C. S. Yadav, M. R. Siddiqui, Anil K. Mantha, Sudha M.
Cowsik, D. Sharma, S. F. Basir and Najma Z. Baquer. ‘Effect of hormone replacement therapy in normalizing age related neuronal markers in different age groups of naturally menopausal rats.’ Biogerentology. 6:345-356 (2005). (Impact factor 3.339)
23. Anjali Dike and Sudha M Cowsik., ‘Membrane induced structure of Scyliorhinin I: A dual NK1/NK2 agonist’. Biophysical Journal.
(2005).PDBID:2NOU (Impact factor 4.137)
24. K Moorthy , UC Yadav, Anil K Mantha, Sudha M Cowsik, D Sharma, SF Basir,
NZ Baquer. ‘Estradiol and progesterone treatments change the lipid profile in naturally menopausal rats from different age groups.’ Biogerontology. 5(6): 411- 419(2004) (Impact factor 3.339)
25. Indu R Chandrashekar, Anjali Dike and Sudha M Cowsik., ‘Membrane induced structure of the mammalian tachykinin Neuropeptide gamma’. Journal of Structural biology. 148: 315-325 (2004) (Impact factor 3.805)
26. . Anil K. Mantha, Indu R. Chandrashekar, Najma Z. Baquer and Sudha M.
Cowsik ‘Three Dimensional Structure of the mammalian Tachykinin peptide Neurokinin B bound to lipid micelles.’ J.Biomol. Struct.Dynamics. 22 (2): 137- 147(2004). PDBID: 1P9F (Impact factor 4.99)
27. Indu R. Chandrashekar, M. Anil Kumar, Anjali Dike and Sudha M. Cowsik
‘Solution Structure of NK2 Agonists’ J.Biomol. Struct.Dynamics, 20 (6): 945 (2003) (Impact factor 4.99) 28. Indu Chandrashekar and Sudha M. Cowsik, ‘Three Dimensional Structure of the mammalian Tachykinin peptide Neurokinin A bound to lipid micelles.’ Biophysical J. 85(6): 4002-4011 (2003). PDBID: 1N6T (Impact factor 4.137)
29. Alessandro Giuliani, Romualdo Benigni, Mauro Colafranceschi, Indu
Chandrashekar and Sudha M. Cowsik. ‘Large contact surface interactions between proteins detected by time series analysis methods: Case study on C- phycocyanins.’Proteins: structure, function and genetics. 51(2): 299-310 (2003). (Impact factor 3.392)
30. C.R.Grace, Indu Chandrasheker and Sudha M. Cowsik, ‘Solution conformation of the tachykinin peptide Eledoisin.’ Biophysical J. 84 (1): 655-664(2002). PDBID: 1MXQ (Impact factor 4.137)
31. Indu R. Chandrashekar, Sara R. Davey, R. Benigni, P.K. Yadava and Sudha M.
Cowsik, ‘A case study of thermostability in phycobiliproteins using algorithm recurrence quantification analysis’Australian J. Plant Physiology, 3:456-461 (2001) (Impact factor 2.929)
32. C.R. Grace, Andrew M. Lynn and Sudha M. Cowsik 'Lipid induced conformation of tachykinin peptide kassinin',J. Biomolecular Str. And Stereodynamics, 18(4): 611-625(2001). PDBID:1MYU (Impact factor 4.99)
33. A.Thakur, H.D. Kumar, Sudha M. Cowsik, ‘Effect of pH and inorganic carbon concentration on growth, glycerol production photosynthesis and dark respiration of Dunaliella salina.’ Cytobios, 102(400): 69-74 (2000) (Impact factor 0.486)
34. S.Mukhopadhyay, Sudha M.Cowsik, Andrew M.Lynn, W.W.Welsh and Allyn
Howlett, ‘Regulation of Gi by CB1 Cannabinoid Receptor C-Terminal juxtamembrance region: Structural requirements determined by Peptide Analysis’ Biochemistry, 38: 3447-3455 (1999). (Impact factor 3.422)
35. Sudha M.Cowsik, Christian Lucke and H.Ruterjans, ‘Lipid induced conformation of substance P’, J. Biomolecular Str. and Stereodynamics, 15: 27-36, (1997). BMRB: 20101 (Impact factor 4.99)
36. Sudha M.Cowsik and S.Swaminathan, ‘A magnetic resonance study of solution conformation of antidepressant drugs of imipramine and anitryptyline: evidence for two receptor sites’, Proc. Nat. Acad. Sci. (India), 66: 46-61, (1996). (Impact factor 0.048)
37. D.R.Shukla and Sudha M.Cowsik ‘Conformational behavior of substance P determined by NMR spectroscopy and CD spectropolarimetry’,Proc. Nat. Acad. Sci. (India), 66: 217-235 (1996). (Impact factor 0.048)
38. Anil Saran , D.R.Shukla and Sudha M. Cowsik, ‘Quantum mechanical studies on neuropeptides:Confornmationa of C-terminal tetra and pentapeptides of tachykinins’ J.Mol.Structure (Theochem) 361: 243-248 (1996) (Impact factor 1.44)
39. Sudha Mahajan, Chritian Lucke and H.Ruterjans,‘Lipid induced conformation of physaelamin’, J. Biomolecular Str. and Stereodynamics 113, (1993). (Impact factor 4.99)
40. Xia Andong, J. Zhu, H. Wu, L. Jiang, ZhangXinyi, Sudha Mahajan,P.S.
Maruthi Sai. ‘Time-resolvespolarizedabsorption of C-phycocyanin from the cyanobacterium Westiellopsis prolifica phycobiliproteins and phycobilisomes from cyanobacteria Westiellopsis Prolifica’ J. Photochem. Photobiol. 19: 111-117 (1993) (Impact factor 2.81)
41. Maria L. Ghirardi, Sudha Mahajan, Sudhir K. Sopory, Marvin Edelman and Autar
K. Mattoo, ‘Photosystem II reaction center particle from Spirodela stroma lamellae’. Journal of Biological Chemistry 268: 5357-5360 (1993). (Impact factor 4.773)
42. P.S. Maruthi Sai, S. Siebzehnrubl, Sudha Mahajan and H. Scheer:
‘Fluorescence and circular dichroism studies from the cyanobacterium Westiellopsis prolifica’.Photochemistry and Photobiology 57: 71-75 (1993). (Impact factor 2.925)
43. Xia Andong, Zhang Xinyi, Hong Qiang, Menj Jiwu, Hou Shangong, M.
Sudha, P.S. Maruthi Sai, I.B. Jha, ‘Spectroscopic characterisation and energy tansfer in C-phycocyanin from cyanobacterium Westiellopsis prolifica’ Science in China (Series B), 35(2): 156-164 (1992). (Impact factor 1.321)
44. . Xia Andong, Zhang Xinyi, M. Sudha, P.S. Maruthi Sai and I.B. Jha, ‘Resonance Raman scattering of phycobilisomes, phycobiliproteins from Cyanobacterium Westiellopsis prolifica’Science in China, 37(2): 550-553 (1992). (Impact factor
45. P.S. Maruthi Sai, S. Siebzenruebl, Sudha Mahajan and H. Scheer,
‘Phycoerythrocyanins from Westiellopsis Prolifica and Nostoc virulare: Characterization of the Phycoviolobilin chromophore in both states.’ Photochemistry and Photobiology 55(1): 119-124 (1992). (Impact factor 2.925)
46. D.R. Shukla and Sudha Mahajan. ‘Conformational behaviour of Tachykinins.’
Expanding Frontiers in Polypeptide and Protein Research, Escom, Netherlands, 1990. pp.85-91.
47. P.S. Maruthi Sai and Sudha Mahajan. ‘Excitation energy transfer among phycobilisomes from phycoerythrin containing strain anabaena variabilis ARM 310’ Current Research in Photosynthesis. Vol.II (Ed, Baltscheffski, M) (1990) Kluwer Academic Publisher, Netherland.
48. Sudha Mahajan, P.S. Maruthi Sai and A. Kumar. ‘A study of Photogluminescence of light harvesting complexes in Cynobacterium’ J. Luminescence, 40 & 41: 231-232 (1988). (Impact factor 1.963)
49. R. Tabeta, Sudha Mahajan, M.Maeda and H. Saito, `Interaction of Antidepressant Drugs with Lipid Bilayers studied by High Resolution 13C and High Power 1H NMR Spectroscopy: the manner of binding as viewed from the differential line broadening of 13C NMR Signals'. Chem. Pharm. Bull., 33(5): 1793-1807 (1985). (Impact factor 1.162)
50. . Gene, A. Morril, Adele B. Kostellow, Sudha Mahajan and Raj K. Gupta, Role of Calcium in regulating intracellular pH following the stepwise release of the metabolic blocks at first meiotic prophase and second meiotic metaphase in amphibian oocytes. Biochimica et Biophysica Acta, 804: 104-117 (1984) (Impact factor 4.66)
51. Gita Subba Rao, Sudha Mahajan and R.K. Mishra, `Calculation of Minimum Energy Conformation of Biomolecules using a Global optimization Technique. IV preferred Conformation and Receptor Maps of Histamine'Int. J. Quantum Chem. , 10: 5-9 (1983) (Impact factor 1.302)
52. S.K. Guha and Sudha Mahajan, `Infrared Relectance from whole Blood Soaked Filter paper and Implications in Haemglobimetry', Med. Biol. Engg., 21: 97-100 (1983). (Impact factor 0.731)
53. Sudha Mahajan, S.K. Guha and M.M. Misro, `A Theoretical and SEM Study of current Mediated Mortality of Spermatozoa',J. Biol. Physics, 10: 113-118 (1982) (Impact factor 1.864)
54. M.M. MIsro, Harpreet Kaur, Sudha Mahajan and S.K. Guha, `An Intravasal Nonocclusive Reversible Contraceptive Device in Male', J. Reprod. Fert., 65: 9-13 (1982) (Impact factor 2.211)
55. K. Verma, M.M. Misro, Harpal Singh, Sudha Mahajan, A.R. Ray and S.K.Guha,
‘Histology of the Rat Vas Deferens after Injection of the Noncclusive Chemical Contraceptive'. J. Reprod. Fertility, 63: 539-542 (1981) (Impact factor 2.211)
56. Sudha Mahajan, S.K. Guha and M.M. Misro,` Biogalyanic cell for male Contraception', Medical Research Engg., 7: 11-15 (1981) (Impact factor 0.731)
57. M.M. Misro, S.K. Guha, Sudha Mahajan and K. Verma. ‘Injectable Nonocclusive Chemical Contraception in the Male-III. Biocompatibility and SEM Studies’. Indian J. Physiol. Pharmacol.,24( 5): 435-436 (1980) (Impact factor 1.953)
58. M.M. Misro, S.K. Guha, Harpal Singh, Sudha Mahajan. A.R. Ray and P
Vasudevan, ‘Injectable Noncclusive Chemical Contraception in the male-I’. Contraception, 20(5):467-474 (1981). (Impact factor 2.590)
59. Sudha Mahajan and K.Sundaram.‘Theoretical studies on tricyclic antidepressants-IV Probable Submolecular Topographic Structure of the Amine Pump Receptor’.Physiol Chem. and Physics 13: 523-526 (1981). (Impact factor 1.711)
60. K.Sundaram and Sudha Mahajan.’Theoretical studies on tricyclic antidepressants-III', Analysis of Stereospecificity’. Physiol Chem. and Physics 13: 387-397 (1981). (Impact factor 1.711)
61. K.Sundaram and Sudha Mahajan. ‘Theoretical studies on tricyclic antidepressants-II' Electronic Structure' on tricyclic Nuclic and Biogenic Amines’.Physiol Chem. And Physics 13: 313-325 (1981). (Impact factor 1.711)
62. K.Sundaram and Sudha Mahajan. ‘Theoretical studies on tricyclic antidepressants-1 Molecular Structure’.Physiol Chem. and Physics, 13: 183- 192 (1980). (Impact factor 1.711)
63. K. Sundaram and Sudha Mahajan. ‘Characterization of norepinephrine channel in adrenergic nerve cell membrane’ Biophysical and Biochemical Information Transfer in Recognition Eds. J.G. Vassileva-Popva and E.V. Jansen, 1979, Plenum Press.
64. . K. Sundaram, Sudha Mahajan and R.K. Mishra. ‘A quantitative approach to the comparison of biomolecular topographies’. Physiol. Chem. and Physics, 6: 469-78 (1974). (Impact factor 1.711)
65. Sudha Mahajan, K. Sundaram and R.K. Mishra, ‘A note on steric correspondence between tricyclic antidepressants and Serotonin’.Physiol. Chem. and Physics, 6: 537-540 (1974). (Impact factor 1.711) Publications in International Proceedings
1. Anjali D. Ganjiwale, Allyn C. Howlett and Sudha M Cowsik. ‘Conformational
Characterization of phosphorylated analogs of a peptide mimetic of the Fourth Cytoplasmic Loop of CB1Cannabinoid Receptor’. 57th Anuual meeting of biophysical society, February 2-6, 2013. Philadelphia, USA
2. Rashmi Jha, A.A Mahdi, Shivani Pandey, Najma Z Baquer and Sudha M Cowsik
‘Neuroprotective Effect of 17β Estradiol on Membrane Fluidity in Aging Brain’ 57th Annual meeting of biophysical society, February 2-6, 2013. Philadelphia, USA
3. Rashmi Jha, Priyanka Mishra, Ranjeet Kumar, Abbas A. Mahdi, Shivani Pandey,
Najma Z.Baquer and Sudha M Cowsik . ‘The Na- K- ATPase activity in response to exogenous Estradiol administration in aging rat brain’. 37th Annual Meeting of Indian Biophysical Society (IBS), January 13-16, 2013, MUMBAI, India.
4. Anjali D. Ganjiwale, Indu R. Chandrashekharan, Khalil Eldeeb, Allyn C. Howlett and
Sudha M Cowsik ‘Phosphorylation of the Fourth Cytoplasmic Loop of the CB1Cannabinoid Receptor: Effects on Structure and Function’. International conference on Biomolecular Forms and Functions, January 8-13, 2013, Bangalore, India
5. Sudha M Cowsik. ‘Tachykinin Neuropeptides: Structure, Dynamics and drug Design’
Indian Science Congress, January 3-7, 2013 Kolkata, India.
6. Gunjan Pandey, Tasneem Fatma, Sudha M Cowsik, Sneha Sudha Komath. ‘Stability,
denaturation and unfolding studies on Phycocyanin’. 38th Midwest/ Southeast photosynthesis meeting, Nov 9-11, 2012, Marshall,USA.
7. Pardeep Kumar, R. K. Kale, Sudha M Cowsik, Najma Z. Baquer. '17-Beta-Estradiol:
A Therapeutic Potential Drug For Parkinson's Disease'. 16th International Congress of Parkinson's disease and Movement Disorders, June 17-21, 2012, Dublin, Ireland
8. Anjali Dike, Indu R. Chandrashekar and Sudha M. Cowsik. ‘Molecular Modeling of
Peptide agonist binding sites for Neurokinin-2 and Neurokinin-3 receptors’, 17th IUPAB International Biophysics Congress October, 2011, Beijing, China
9. Rashmi Jha, Abbas A. Mahdi, Sudha M Cowsik, Najma Z Baquer. ‘Role of
Neurokinin B (NKB) and Amyloid beta (25-35) in estradiol treated ageing rat brain synaptosomes’ .XXIXAnnual Conference of Indian Academy of Neurosciences, October 2011, Delhi, India
10. Sudha M Cowsik. ‘Tachykinin Peptides and Receptor Modelling’. International
Training in Global Infectious Diseases (GID) Workshop of the seattle-India Joint Research Training Program Advanced Technologies and Research Proposal Development, February 11, 2011 New Delhi
11. Anjali Dike, Allyn C. Howlett and Sudha M. Cowsik. ‘Structural characterization of
peptide mimetic of the fourth cytoplasmic loop of CB1 cannabinoid receptor’. Cannabinoids in biology and medicine, October 2010, Jeruselum, Israel
12. Anjali Dike, Indu R. Chandrashekar, Allyn C. Howlett and Sudha M. Cowsik. ‘Role
of phosphorylation in the conformation of the fourth cytoplasmic loop of CB1 Cannabinoid receptor’. ICRS meeting, July 2010, Lund, Sweden
13. Anjali Dike, Gita Subba Rao and Sudha M. Cowsik . ‘Molecular Modelling of
NeurokininB and Neurokinin3 receptor complex’. XXIV ICMRBS meeting, August 2010, Cairns, Australia
14. R. Christy Rani Grace and Sudha M. Cowsik. ‘Three dimensional structure of
nonmammalian tachykinin Physalaemin in lipid micelles’. British Biophysical society meeting, July 2010 Cambridge, UK
15. R. Christy Rani Grace, Sudha M. Cowsik and Allyn C. Howlett . ‘Conformation of a
peptide mimetic of the fourth cytoplasmic loop of the CB1 cannabinoid receptor’. NMRS 09 meeting, February 2009, Hyderabad, India
16. R. Chandrashekar, Anil K. Mantha, Anjali Dike and Sudha M. Cowsik. ‘Structural
features of Neurokinin-2 receptor selective peptide agonists’. XXIIIrd International Conferences on Magnetic Resonance in Biological Systems, August 2008, San Diego, USA
17. Indu R. Chandrashekaran, Gita Subba Rao and Sudha M. Cowsik. ‘Structural features
of Neurokinin receptor selective peptides and their role in Neurokinin receptor selectivity’.16th International Biophysics Congress (IUPAB), February 2008, Long Beach, California, USA
18. Anjali Dike and Sudha M Cowsik. ‘Structural Charcterisation of Neurokinin 3
receptor selective agonist Scyliorhinin ΙΙ bound to DPC Micelles’. Albany 2007 Conversation, June, 2007. Albany, USA.
19. Gunjan Pandey, Sudha M. Cowsik, Tasneem Fatema and Sneha Sudha komath.
‘Lectin-Phycocyanin Conjugates: A new tool for tumour identification’ .Indian Biophysical Society Meeting, February, 2007, Delhi,India
20. Syed Asif Hassan, Preeti Gupta, Sudha M Cowsik, Lata Chauhan, Aparna Dixit and
Ritu Barthwal. ‘DNA – Anticancer Drug Interaction Studies Using Sequence Selective Inhibition of Restriction Endonucleases’. Indian Biophysical Society Meeting, February, 2007, Delhi, India
21. Anjali Dike and Sudha M. Cowsik. ‘Structural characterization of Tachykinin peptide
-Neurokinin receptor interaction: A molecular modeling and spectroscopic investigation’. XXIInd International Conference on Magnetic Resonance in Biological Systems, August, 2006, Gottingen, Germany
LANDTAG MECKLENBURG-VORPOMMERN Drucksache 6/603 6. Wahlperiode 11.05.2012 KLEINE ANFRAGE der Abgeordneten Silke Gajek, Fraktion BÜNDNIS 90/DIE GRÜNEN Grippemittel und ANTWORT der Landesregierung Das Grippemittel Tamiflu wurde im Zusammenhang mit dem Beginn der Vogelgrippe 2005/2006 durch die Länder in großem Umfang eingekauft und gelagert. Schätzwerte gehen von Vo
QUESTIONS AND ANSWERS ON THE REVIEW OF PROZAC FOR USE IN CHILDREN AND ADOLESCENTS The Committee for Medicinal Products for Human Use (CHMP) has completed its arbitration review of Prozac (fluoxetine) and associated namesextend its use in the treatment of children suffering from depression, provided that the marketing authorisation holder (MAH), Eli Lilly, carries out additional studie