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A selective emulsifiable concentrate herbicide for the ‘n Selektiewe emulgeerbare konsentraat onkruiddoder vir post emergent control of certain broadleaf weeds in the die na-opkom beheer van sekere breëblaaronkruide in ACTIVE INGREDIENT / AKTIEWE BESTANDDEEL
Bromoxynil (nitrile) 400 g / ℓ Bromoksiniel (nitriel) as the octanoate as die oktanoaat Batch number ……………. Lotnommer Date of Manufacture ………………. Datum van Vervaardiging BROMOTRIL 400 EC is the registered trademark of Makhteshim-Agan Israel.
BROMOTRIL 400 EC is die geregistreerde handelsmerk van Makhteshim-Agan, Israel.
WARNINGS Allow the following withholding periods between application and grazing or feeding. Barley, oats, Wheat and Lucerne Poisonous when swallowed, inhaled or absorbed through the skin. Store away from food and feeds. Keep out of reach of children. Flammable – Do not store near open flame.

Although this remedy has been extensively tested under a large variety of conditions the
registration holder does not warrant that it will be efficacious under all conditions because the
action and effect thereof may be affected by factors such as abnormal climatic and storage
conditions; quality of dilution water; compatibility with other substances not indicated on the
label and the method, time and accuracy of application. The registration holder furthermore
does not accept responsibility for damages to crops, vegetation, the environment or harm to
man or animal or for lack of performance of the remedy concerned due to failure of the user to
follow the label instructions or to the occurrence of conditions which could not have been
foreseen in terms of the registration. Consult the supplier in the event of any uncertainty.

Wash with soap and water after use or accidental skin contact. Do not eat, drink or smoke whilst mixing or applying the product or before washing hands and face. Avoid spraydrift onto other crops, grazing, rivers, dams and areas not under treatment. Clean applicator before using it with other remedies. Dispose of wash water where it will not contaminate crops, grazing, rivers, dams, etc. Prevent contamination of feeds, drinking water and eating utensils. IMPORTANT: Invert the empty container over the spray or mixing tank and allow to drain for at least 30 seconds after the flow has slowed down to a drip. Thereafter rinse the container three times with a volume of water equal to a minimum of 10 % of that of the container. Add the rinsings to the contents of the spray tank before destroying the container in the prescribed manner. Destroy empty container by perforation and flattening and never use for any other purpose. DIRECTIONS FOR USE: Use only as directed Do not spray when weeds have been subjected to moisture or other stress. Apply only during moist conditions which enhance active weed growth. Since BROMOTRIL 400 EC is a contact herbicide, thorough wetting of the foliage of the weeds is essential. Only weeds present at the time of spraying will be controlled and not those which may germinate later. The weeds should not have passed the 6-leaf stage at the time of spraying. Yellowing of Lucerne leaves or leaf scorching of grain crops may occur after application, but yields will not be affected. Do not apply wetting agent when spraying maize, sorghum or Lucerne. For aerial application, the higher of recommended rates should always be used BROMOTRIL 400 EC is compatible with MCPA AND Atrazine 500 SC formulations. If any uncertainty exist regarding compatibility contact the supplier. 2. Half fill the spray tank with clean water. Mix the required quantities of BROMOTRIL 400 EC with a small amount of water and add to the spray tank while agitating. Fill the spray tank with water while agitation is kept up. METHOD OF APPLICATION Aerial application: Aerial application of BROMOTRIL 400 EC may only be done by a registered Aerial Application Operator using a correctly calibrated, registered aircraft according to the instructions of SABS Code 0118 (Aerial Application of Agricultural Pesticides). Ensure that the spray mixture is distributed evenly over the target area and that the loss of spray material during application is restricted to a minimum. It is therefore essential that the following criteria be met: • Volume: A spray mixture volume of 40 (at least) to 50 (recommended) litres per hectare is recommended. As this product has not been evaluated at a reduced volume rate, the registration holder cannot guarantee efficacy, or be held responsible for any adverse effects if this product is applied aerially at a lower volume rate than recommended above. • Droplet coverage: 40 to 60 droplets per cm² must be recovered at the target area. • Droplet size: A droplet spectrum with a VMD of 350 to 400 microns is recommended. Limit the production of fine droplets less than 150 microns (high drift and evaporation potential) to a minimum. • Flying height: Maintain the height of the spray boom at 3 to 4 metres above the target. Do not spray when aircraft dives, is in a climb or when banking • Use suitable atomising equipment that will produce the desired droplet size and coverage, but which will ensure the minimum loss of product. The spraying system must produce a droplet spectrum with the lowest possible Relative Span. • Position all the atomisers within the inner 60 to 75 % of the wingspan to prevent droplets from • The difference in temperature between the wet and dry bulb thermometers, of a whirling • Stop spraying if the wind speed exceeds 15 km/h. • Stop spraying under turbulent, unstable and dry conditions during the heat of the day. • Spraying under temperature inversion conditions (spraying in or above the inversion layer) and/or high humidity conditions (relative humidity 80 % and above) may lead to the following: reduced efficacy due to suspension and evaporation of small droplets in the air damage to other sensitive crops and/or non-target areas through drifting of the suspended spray cloud away from the target field. • Ensure that the Aerial Spray Operator knows exactly which fields to spray. • Obtain an assurance from the Aerial Spray Operator that the above requirements will be met and that relevant data will be compiled in a logbook and kept for future reference. A. TRACTOR MOUNTED SPRAYER
Use a conventional sprayboom with flat fan nozzles. Use a low pressure of 100 – 300 kPa, so
that a coarse droplet spray is formed. Ensure that even coverage is obtained. At least 300 liter to
600 liter water / ha will be necessary.
Wheat, Barley and
The cereal seedlings should be between the 3-leaf and the end of the stooling stage. Do not spray before the 3-leaf stage and from the beginning of the tillering stage onwards. The younger the weeds are and more actively they are growing the lower the dosage. When the weeds are reaching the 6-leaf stage and when growth is slowed down by drought, the higher rate should be used. Also use the higher dosage for aerial application. . Established Lucerne
Apply after the Lucerne has been cut. Use
the higher rate when the weeds stand is
dense and / or under dry conditions.
WARNINGS: Yellowing of Lucerne leaves
may occur after application, but this is of a
temporary nature and will disappear after a
few days without affecting the crop.
Apply as ground or aerial spray when the weeds are fully emerged, but not older than the 6-leaf stage (3-leaf stage for problem weeds listed in separate panel). Do not apply to maize younger than the 4-leaf stage. Use higher dosage rate for aerial application. Apply as ground or aerial spray when the weeds are fully emerged, but not older than the 6-lefa stage (3-leaf stage for problem weds listed in separate panel). The atrazine rate should be in accordance with the degree of persistence desired. Do not apply in maize younger than the 4-leaf stage. Apply as ground or aerial spray when the weeds are fully emerged, but not older than the 6-leaf stage. Can be apllied at any stage of development of maize from emergence to flowering. If crops are taller than 40 cm, directed spraying is recommended so that better wetting of weeds is obtained. Do not apply under cold, wet conditions as this may result in damage to the crop. Grain sorghum
Follow the instructions for application in Follow the instructions for application in
Important notes:

1. Do not apply BOMOTRIL 400 EC when weeds are older than specified, as this will 2. The use BROMOTRIL 400 EC in combination with wetting agents is not advisable as 3. Avoid application when the weeds are covered with heavy dew, or when the wind is 4. Ensure thorough coverage of weeds. 5. Weeds which have not germinated at the time of application will not be controlled. 6. Poor weed control may result if BROMOTRIL 400 EC is applied when the weeds are under moisture or stress. Apply only during favourable climatic conditions when the weeds are actively growing. 7. Under certain climatic conditions BROMOTRIL 400 EC may cause some leaf scorch to grain crops. However, yields will not be effected. 8. When BROMOTRIL 400 EC is mixed with any other product, the information on the label of that product must be carefully consulted and the instructions followed. Consult your representative before mixing BROMOTRIL 400 EC with other chemicals. 9. WAITING PERIOD: When BROMOTRIL 400 EC is mixed with ATRAZINE SC, the
following waiting period must be adhered to before Atrazine sensitive crops van be planted. Six months when 1 l Atrazine / ha is used Nine months when 2 l Atrazine / ha is used
For more information consult the ATRAZINE SC label.
NOTE: This product controls some annual broadleaf weeds. Other broadleaf weeds that were not
present during the development trials with the product, may possibly also be controlled to a certain
degree. The Registration holder does not accept any responsibility for unlisted weeds.
Acanthospermum hispidum
Slegs saadlob tot 3-blaarstadium / Cotyledon to 3-leaf stage only Spuit Tribulus terrestris alvorens die plantjie se deursnee 25 mm oorskry Spray Tribulus terrestis before the diameter of the seedling exceeds 25 mm WAARSKUWINGS Laat die volgende onthoudingsperiodes toe tussen die laaste toediening en beweiding of voer: Gars, Hawer, Koring en Lusern Giftig indien ingesluk, ingeasem of deur vel geabsorbeer word. Berg in ‘n koel plek weg van voedsel en voer. Vlambaar – Hou weg van oop vlamme.

Alhoewel hierdie middel omvattend onder 'n groot verskeidenheid toestande getoets is,
waarborg die registrasiehouer nie dat dit onder alle toestande doeltreffend sal wees nie,
aangesien die werking en effek daarvan beïnvloed kan word deur faktore soos abnormale
grond-, klimaats- en bergingstoestande; kwaliteit van verdunningswater; verenigbaarheid
met ander stowwe wat nie op die etiket aangedui is nie en die voorkoms van weerstand van
die onkruid teen die betrokke middel sowel as die metode, tyd en akkuraatheid van
toediening. Verder aanvaar die registrasiehouer nie verantwoordelikheid vir skade aan
gewassse, plantegroei, die omgewing of vir nadelige effek op mens of dier of vir 'n gebrek
aan prestasie van die betrokke middel as gevolg van die versuim van die gebruiker om
etiketaanwysings na te kom of as gevolg van die ontstaan van toestande wat nie kragtens die
registrasie voorsien kon word nie. Raadpleeg die verskaffer in die geval van enige


Moenie die dampe of sproeinewel inasem nie. Was besoedelde klere daagliks. Was met seep en water na gebruik of na velkontak. Moenie eet, rook of drink tydens vermenging of bespuiting, of voordat hande en gesig gewas en skoon klere aangetrek is nie. Voorkom besoedeling van ander gewasse, weiding, riviere, damme en enige gebied nie onder behandeling nie. Maak toedieningsapparaat deeglik skoon na gebruik en gooi spoelwater uit waar dit nie voedsel, weiding, riviere of damme sal besoedel nie. Voorkom besoedeling van voedsel, voer, drinkwater en eetgerei. BELANGRINK: Keer die leë houer om oor die spuittenk of mengbak en dreineer vir minstens 30 sekondes nadat die vloei tot ‘n gedrup verminder het. Spoel die houer daarna drie keer uit met ‘n volume water gelykstaande aan ‘n minimum van 10 % van die houer. Gooi die spoelwater by die inhoud van die spuittenk voordat die houer op die voorgeskrewe wyse vernietig word. Vernietig leë houer deur gate daarin te maak en plat te druk. Moet vir geen ander doel gebruik word nie. GEBRUIKSAANWYSINGS: Gebruik slegs soos aangedui Moet nie toedien wanneer onkruide aan vog- of ander stremminge onderworpe was , of is nie. Dien dus slegs toe onder vogtige toestande wat aktiewe onkruidgroei bevoordeel. Aangesien BROMOTRIL 400 EC ‘n kontakonkruiddoder is, is dit noodsaaklik dat die blare van die onkruide deeglik benat word. Slegs die onkruide wat teenwoordig is, ten tye van bespuiting, sal beheer word en nie die onkruide wat later mag ontkiem nie. Ten tye van bespuiting moet die onkruide nog nie verby die 6-blaarstadium ontwikkel het nie. Vergeling van lusernblare of blaarskroei by graangewasse mag na toediening voorkom, maar opbrengste sal nie beïnvloed word nie. Moenie benatters byvoeg wanneer mielies, sorghum of lusern bespuit word nie. In geval van lugbespuiting behoort slegs die hoër dosis gebruik te word. BROMOTRIL 400 EC is mengbaar met MCPA en Atrasien 500 SC formulasies. Tree met die verskaffer in verbinding as enige onsekerheid oor die verenigbaarheid bestaan. 2. Maak die spuittenk halfvol met skoon water. Meng die aanbevole hoeveelheid water en voeg in die tenk terwyl geroer word. Vul die spuittenk met water terwyl gedurig geroer word. METODE VAN TOEDIENING Lugtoediening: BROMOTRIL 400 EC kan slegs deur ‘n geregistreerde Lugbespuitingsperateur met ‘n korrek gekalibreerde, geregistreerde vliegtuig volgens die instruksies van SABS Kode 0118 (Aerial Application of Agricultural Pesticides) uit die lug bespuit word. Verseker dat die spuitmengsel eweredig oor die teikenarea versprei word, en die verlies aan spuitmengsel tydens toediening tot ‘n minimum beperk word. Dit is daarom belangrik om aan die volgende vereistes te voldoen: Volume: ‘n Spuitmengsel volume van 40 (minimum) tot 50 (aanbevole volume) liter per ha word aanbeveel. Hierdie produk is nie teen ‘n verlaagde volume getoets nie. Die registrasiehouer kan nie effektiteit waarborg, of verantwoordelik gehou word vir enige nadelige effekte indien hierdie produk teen ‘n laer volume, as hierbo aanbeveel, toegedien word nie. Druppel bedekking: 40 tot 60 druppels per cm² moet op die teikenarea herwin word. Druppelgrootte: ‘n Druppelspektrum met ‘n VMD van 350 tot 400 mikrons word aanbeveel. Beperk die produksie van druppels kleiner as 150 mikrons (hoë drywing en verdampingspotensiaal) tot ‘n minimum. Vlieghoogte: Handhaaf die hoogte van die spuitbalk bo die teiken op 3 tot 4 meter. Moet nie spuit wanneer die vliegtuig duik nie, uitklim of draai nie. Gebruik geskikte atomiseringsapparaat wat die vereiste druppelgrootte en bedekking sal produseer, maar die minste verlies van produk verseker. Die spuitstelsel moet ‘n druppelspektrum met die kleinste moontlike Relatiewe Span produseer. Plaas al die atomiseerders in die binnste 60 tot 75 % van die vlerkspan om te verhoed dat druppels binne-in die vlerkpuntvorteks beweeg. Die verskil in temperatuur tussen die nat- en droëboltermometer van ‘n swaaihigrometer, moet nie 8°C oorskry nie. Stop bespuiting indien die windspoed 15 km/h oorskry. Stop bespuiting tydens turbulente, onstabiele en droë toestande gedurende die hitte van die dag. Bespuiting onder temperatuur inversie toestande (deur bo of binne die inversie laag te spuit) en/of hoë lugvog toestande (relatiewe humiditeit 80% en meer) mag tot volgende probleme aanleiding gee: a) verlaagde effektiwiteit aangesien die druppels as ‘n wolk in die lug bly hang en moontlik verdamp (onvoldoende bedekking op teiken). b) skade aan nie-teiken gewasse of sensitiewe areas as gevolg van wegdrywing van die Verseker dat die Lugbespuitingsoperateur presies weet watter lande bespuit moet word. Dit is noodsaaklik om ‘n versekering van die Lugbespuitingsoperateur te verkry dat aan al die bogenoemde vereistes voldoen sal word en dat data van belang in ‘n logboek saamgevat is vir toekomstige verwysing. A. TREKKERGEMONTEERDE SPUITE Gebruik ‘n konvensionele spuitbalk met platwaaierspuitpunte. Gebruik ‘n lae druk van tussen 100 en 300 kPa sodat ‘n goeie bedecking verkry word, waarvoor ten minste 300 tot 600 liter water per ha nodig is. Koring, Gars en
Die graansaailinge behoort tussen die 3-blaar en die end van stoelstadium te wees. Moet nie voor die 3-blaarstadium en vanaf die begin van pypstadium spuit nie. Hoe jonger die onkruide is en hoe meer aktief dit groei, hoe laer die dosis. Wanneer die onkruide begin om die 6-blaarstadium te bereik en wanneer die groeitempo afneem as gevolg van droogte, behoort die hoer dosis gebruik te word. Dien deur middel van grond- of lugbespuiting toe. Gevestigde Lusern
Dien toe nadat die lusern gesny is. Gebruik die hoër
hoeveelheid wanneer die onkruide dig staan en / of
onder droë toestande.
WAARSKUWING: Vergeling van die lusernblare
mag voorkom na toediening, maar dit is van
verbygaande aard en sal na ‘n paar dae verdwyn
sonder om enige skade aan die gewas te berokken.
Dien deur middel van grond- of lugbespuiting toe wanneer die onkruid volledig opgekom het, maar nie ouer as die 6-blaarstadium is nie (3-blaarstadium vir probleem onkruide soos aangedui) Moenie toedien op mielies jonger as die 4-blaarstadium nie. Gebruik die hoër dosis vir lugtoediening. Dien deur middel van grond- of lugbespuiting toe wanneer die onkruid volledig opgekom het, maar nie ouer as die 6-blaarstadium is nie (3-blaarstadium vir probleemonkruide soos aangedui.) Die atrasiendosis moet in ooreenstemming wees met die mate van nawerking wat verlang word. Moet nie toedien op mielies jonger Dien deur middel van grond- of lugbespuiting toe wanneer die onkruid volledig opgekom het, maar nie EC plus 1,0 ℓ MCPA ouer as die 6-blaarstadium is nie. Kan in enige (Kaliumsout) ontwikkelingstadium van die mielies toegedien word. Indien die gewas hoër as 40 cm is word gerigte bespuiting aanbeveel om beter benatting van die onkruid te verseker. Vermy toediening tydens koue, nat toestande aangesien gewasbeskadiging kan voorkom. Graansorghum
Volg die instruksies soos vir die toediening in mielies, maar moet nie deur middel van lugbespuiting 0,850 BROMOTRIL Volg die instruksies soos vir die toediening in 400 EC plus mielies, maar moet nie deur middel van lugbespuiting Belangrike notas:

1. BROMOTRIL 400 EC moet nie toegedien word indien die onkruid ouer is as wat
gespesifiseer is nie, aangesien dit sal lei tot swak onkruidbeheer. 2. BROMOTRIL 400 EC moet nie saam met benattingsmiddels gebruik word nie, aangesien dit skade aan die gewasse kan veroorsaak. 3. Vermy toediening wanneer die onkruide bedek is met swaar dou of wanneer die wind 4. Maak seker dat deeglike bedekking van die onkruid verkry word. 5. Onkruide wat nog nie ontkiem het tydens bespuiting nie, sal nie beheer word nie. 6. Swak onkruidbeheer mag verkry word indien BROMOTRIL 400 EC toegedien word wanneer die onkruid onderhewig is aan vog- en ongunstige klimaats stremmings. Dien slegs toe onder gunstige toestande wanneer onkruid aktief groei. 7. Onder sekere omgewingstoestande kan BROMOTRIL 400 EC ‘n mate van blaarskroei op graangewasse veroorsaak. Graanopbrengs sal egter nie beïnvloed word nie. 8. Wanneer BROMOTRIL 400 EC met enige ander produk gemeng word, moet die inligting op die produk se etiket noukeurig gelees word en die gebruiksaanwysings gevolg word. Raadpleeg eers die verteenwoordiger voordat u BROMOTRIL 400 EC met ander chemikalieë meng. 9. WAGPERIODE: Wanneer BROMOTRIL 400 EC met ATRASIEN SC gemeng word, geld die volgende wagperiodes voordat ‘n opvolggewas wat sensitief is voor Atrasien geplant mag word. Ses maande wanneer 1 l Atrasien / ha toegedien word Nege maande wanneer 2 l Atrasien / ha toegedien word Vir meer besonderhede raadpleeg die ATRASIEN SC etikette. NOTA: Hierdie produk beheer sekere eenjarige breëblaaronkruide. Ander breëblaaronkruide wat nie tydens die ontwikkelingsproewe met die middel voorgekom het nie, kan ook moontlik in ‘n meerdere of mindere mate beheer word. Die Registrasiehouer aanvaar egter geen aanspreeklikheid ten opsigte van ongelyste onkruide nie.
Onkruide wat normaaalweg deur BROMOTRIL 400 EC beheer word:
Weeds which are normally controlled by BROMOTRIL 400 EC:

Slegs saadlob tot 3-blaarstadium / Cotyledon to 3-leaf stage only Spuit Tribulus terrestris alvorens die plantjie se deursnee 25 mm oorskry Spray Tribulus terrestris before the diameter of the seedling exceeds 25 mm.


Post-graduate student C&MB seminar this Friday Friday 10rd August 12noon-12:50pm AM101 Speakers: John Gibbins and Christina Roberts John Gibbins 2 ½ years into PhD Supervisors: Ian Hermans and Troels Petersen (The Malaghan Institute of Medical Research) Title: CD8  + Langerin+ Dendritic Cells Activate and Maintain CD8 T Cell Populations After Adoptive Tr

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RENCANA PROGRAM KEGIATAN PEMBELAJARAN SEMESTER TEKNOLOGI SEDIAAN FARMASI [ 5(1) ] A. PERENCANAAN PEMBELAJARAN Deskripsi singkat matakuliah Teknologi Sediaan Farmasi Matakuliah Teknologi Sediaan Farmasi Fisika berisi pokok-pokok bahasan rancangan bentuk sediaan; garis besar formulasi sediaan; hubungan rute/cara pemberian dengan bentuk sediaan dan tahap-tahap pengembangan sediaan;

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