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Microsoft word - contraceptive hormones mutating fish in st.doc

Contraceptive Hormones Mutating Fish in St. Lawrence River
By Hilary White
MONTREAL, September 18, 2008 (LifeSiteNews.com) - Estrogen from birth control pills in
highly populated areas of Canada is washing into the water table and flooding the St. Lawrence
River, a new study has found. University of Montreal researchers said that the St. Lawrence
River near Montreal has an alarmingly high level of estrogens that are mutating male fish.
Downstream from the island of Montreal, one of Canada's most densely populated urban areas,
estrogen levels in the water are "about 100 times more than the level known to have significant
endocrine-disrupting effects," Sebastien Sauve, a professor of environmental chemistry, told the
CBC.
The primary source of the estrogens is the contraceptive pill and other artificial hormones, said
the researchers. "They're really pharmaceuticals, which are used either as contraceptives or in
hormone replacement therapy," Sauve said.
Scientists have regularly reported in recent years that the excess of artificial hormones in the
water system has caused lack of sexual differentiation among fish and other wildlife and a loss of
their capacity to procreate.
Excess drugs that the body does not metabolise are excreted and flushed into sewage treatment
plants, and then into streams and lakes, where they can be taken up by wildlife and drinking
water supplies. Scientists are growing increasingly concerned about the long-term impact of
estrogens, called "endocrine disruptors", and their impact on the development of fish,
amphibians and reptiles.
The CBC reports that other research at Quebec's National Institute for Science Research has
found ovaries in the testes of one-third of the males of a species of minnow in the same part of
the river that the new study examined.
In 2006, the United States Geological Survey undertook the first nation-wide study of estrogens
as a water pollutant and found a dramatic upsurge in the number of male fish growing female
reproductive parts. A survey of bass in the Potomac River found almost 100 percent of the
smallmouth bass species were feminized, or had eggs in their testes.
In 2001 and 2003, a group led by University of New Brunswick ecotoxicologist Karen Kidd
spiked the water of a Canadian lake with the type of estrogen found in birth control pills, to find
out how the hormone might impact the aquatic animals.
They added the hormone at a level of six parts per trillion, which is similar to levels that have
been found in treated sewage water. The most alarming finding was that the lake's population of
the common Fathead minnow plummeted from thousands to almost zero, because estrogen so
thoroughly disrupted the minnow's reproductive abilities.
Read related LifeSiteNews.com coverage: The Pill: "the largest unregulated human trial that's ever been conducted" http://www.lifesitenews.com/ldn/2006/mar/06030705.html Hormonal Contraceptives Pollute Drinking Water - Environmentalists Turn a Blind Eye http://www.lifesitenews.com/ldn/2007/jul/07071105.html Study Confirms Estrogen in Water from the Pill Devastating to Fish Populations http://www.lifesitenews.com/ldn/2008/feb/08021805.html

Source: http://omsoul.ca/offthepress/Contraceptive%20Hormones%20Mutating%20Fish%20in%20St.pdf

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Review and Analysis of Pfizer, Inc. v. Ranbaxy Laboratories Limited, F.3d 1284; 2006U.S. App. LEXIS 19416; 79 USPQ2d 1583 (Fed. Cir. August 2, 2006)by Richard Neifeld, Neifeld IP Law, PC, Alexandria VA1In Pfizer, Inc. v. Ranbaxy Laboratories Limited, F.3d 1284; 2006 U.S. App. LEXIS19416; 79 USPQ2d 1583 (Fed. Cir. August 2, 2006), the CAFC held patent claim 6 invalid underthe fourth paragraph o

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