2012 ANTIBIOTIC SUSCEPTIBILITY PROFILES s u s s s c s u e a a s s c u tre e s c s c ia lis ilu n s r / u u o s c e c n lla a a o o te c c u c u z o n tic o e h lla s c c c e ly c o x p n m in li u ilis c s o tic lo re g m rrh o e o g o ie b a o c y y u to o me to u ra d s te b tia c lo h h a p y a p e o ta m flu u ru .c b p ira ro y p p H a e E ro ro tre e h n M c a in e ro a le P m rra te p p ta S tre p H s K te n e n a S S P ta E S E S s Number of Isolates PENICILLIN FLUCLOXACILLIN AMOXYCILLIN AMOX / CLAV CEFACLOR COTRIMOXAZOLE ERYTHROMYCIN CLINDAMYCIN TETRACYCLINE GENTAMICIN CIPROFLOXACIN NITROFURANTOIN TRIMETHOPRIM
The p ercentage of organisms susceptible to an antibiotic is recorded (with the sample size in the first row of the table).
(e.g. Staphylococcus aureus vs. flucloxacillin 90% susceptible, n=3874)
S = Not specifically tested, but known to be ordinarily susceptible.
R = Organism resistant or antibiotic inappropriate V = Variable susceptibility.
a. S. aureus susceptible to flucloxacillin can be considered susceptible to amoxycillin-clavulanate and cefaclor. Methicillin resistant Staphylococcus aureus (i.e. MRSA)
are resistant to all beta-lactam antibiotics (penicillins, cephalosporins, carbapenems).
b. Clindamycin susceptibility is extrapolated from the erythromycin result. c. S. pneumoniae susceptible to penicillin can be considered susceptible to amoxycillin, amoxycillin-clavulanate, cefaclor, cefuroxime, cefotaxime, ceftriaxone,
cefpodoxime, imipenem and meropenem. Confirmation of penicillin resistance (reduced susceptibility) in S. pneumoniae requires MIC testing. (Please note this figure includes both penicillin susceptible and intermediately susceptible isolates). S.pneumoniae isolates intermediately susceptible to penicillin are resistant to cefaclor. In 2012 our S. pneumoniae isolates demonstrated the following pattern of susceptibility to penicillin: 81% = Susceptible, 9% = Intermediate, 10% = Resistant. However, of the resistant strains only a few had a penicillin MIC > 4mg/L, and penicillins (amoxycillin) are effective against strains with MIC <= 4mg/L, unless they are causing meningitis.
d. Amoxycillin and amoxycillin-clavulanate susceptibility is extrapolated from the penicillin result. e. Erythromycin is not recommended for treatment of infections thought to be due to H. influenzae. f.
S. saprophyticus causing urinary tract infections will usually respond to amoxycillin-clavulanate and cephalosporins. (Up to 50% of isolates are resistant to amoxycillin).
g. Cotrimoxazole susceptibility is extrapolated from the trimethoprim result. h. Derived from nalidixic acid result.
MOST LIKELY BACTERIAL PATHOGENS IN COMMON CONDITIONS
1. RESPIRATORY INFECTIONS 2. URINARY TRACT INFECTION
Pharyngitis - Streptococcus pyogenes (Gp A
3. IMPETIGO / CELLULITIS
Acute exacerbation of Chronic Bronchitis
Haemophilus influenzaeMoraxella catarrhalis
BERGER&TWERSKI FINAL TYPE.DOC 6/29/2006 9:41 AM FROM THE WRONG END OF THE TELESCOPE: A RESPONSE TO PROFESSOR DAVID BERNSTEIN I. From the Wrong End of the Telescope. 1985 A. A Different Perspective on Bendectin . 1985 B. The Parlodel Saga . 1987 II. Bernstein’s Slippery Slope Arguments. 1989 A. Informed Choice Warnings Are Not Worthless . 1989 B. Bypassing Daubert Wil
COMMENTARY Biological Diversity: genetic resources” also includes newly developed varieties and special genetic A Common Heritage stocks. The developing countries’ efforts to keep all types of breeding material within the public domain were at variance with the demand of the developed coun-K Divakaran Prathapan, Priyadarsanan Dharma Rajantries to provide and respect intellectual