Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Microsoft word - regal no grain salmon - 80592.doc

GUARANTEED ANALYSIS:
Crude Protein, min 30.0%
Crude Fiber, max 4.5% Moisture, max 10.0%
INGREDIENT LIST:
Lamb Meal, Buffalo Meal, Field Pea, Tapioca, Sweet Potato,
Canola Oil, Whitefish Meal, Potato Protein, Carrots, Celery, Beet, Parsley, Lettuce, Water Crest, Spinach, Egg, Brewers Dried Yeast, Natural Flavor, Lecithin, Monosodium Phosphate, DL-Methionine, L-Lysine, Choline Chloride, Propionic Acid, Yucca Schidigera Extract, Lactobacillus Acidophilus Fermentation Product Dehydrated, Glucosamine HCL.
Vitamin & Mineral Premix:
Vitamin E Supplement, Mineral Oil, Ascorbic Acid, Niacin Supplement,
Organic Dried Kelp, d-Calcium Pantothenate, Riboflavin Supplement, Biotin, Vitamin B12 Supplement, Thiamine Mononitrate, Vitamin A Acetate, Pyridoxine Hydrochloride, Citric Acid, Vitamin D3 Supplement, Folic Acid, Potassium Chloride, Iron Sulfate, Zinc Sulfate, Zinc Proteinate, Iron Proteinate, Copper Sulfate, Zinc Oxide, Manganese Sulfate, Manganese Proteinate, Copper Proteinate, Manganous Oxide, Selenium, Calcium Iodate. Fresh, clean water should be kept available to the dog at all times. GUARANTEED ANALYSIS:
Crude Protein, min 30.0% Crude Fat, min 14.0% Moisture, max 10.0%
INGREDIENT LIST:
Chicken Meal, Sweet Potato, Tapioca, Split Pea, Duck Meal, Chicken
Fat (Preserved with Mixed Tocopherols), Whitefish Meal, Carrots,
Celery, Beets, Parsley, Lettuce, Watercress, Spinach, Egg, Brewers Dried Yeast, Flax Seed, Natural Flavor, Lecithin, Salt, Menhaden Fish Oil, DL-Methionine, Canola Oil, L-Lysine, Calcium Carbonate, Propionic Acid, Yucca Schidigera Extract, Lactobacillus Acidophilus Fermentation Product Dehydrated, Glucosamine HCL.
Vitamin & Mineral Premix:
Vitamin E Supplement, Mineral Oil, Ascorbic Acid, Niacin Supplement, Organic Dried Kelp, d-Calcium Pantothenate, Riboflavin Mononitrate, Vitamin A Acetate, Pyridoxine Hydrochloride, Citric Acid, Vitamin D3 Supplement, Folic Acid, Potassium Chloride, Iron Sulfate, Zinc Sulfate, Zinc Proteinate, Iron Proteinate, Copper Sulfate, Zinc Oxide, Manganese Sulfate, Manganese Proteinate, Copper Proteinate, Manganous Oxide, Selenium, Calcium Iodate. Fresh, clean water should be kept available to the dog at all times. GUARANTEED ANALYSIS:
Crude Protein, min 30.0%
Crude Fiber, max 4.0% Moisture, max 10.0%
INGREDIENT LIST:
Salmon Meal, Sweet Potato, Tapioca, Field Pea, Whitefish Meal,
Canola Oil, Buffalo Meal, Carrots, Celery, Beets, Parsley, Lettuce, Water Crest, Spinach, Egg, Brewers Dried Yeast, Natural Flavor, Lecithin, Calcium Carbonate, Monosodium Phosphate, DL-Methionine, L- Lysine, Choline Chloride, Propionic Acid, Yucca Schidigera Extract, Lactobacillus Acidophilus Fermentation Product Dehydrated, Glucosamine HCL.
Vitamin & Mineral Premix:
Vitamin E Supplement, Mineral Oil, Ascorbic Acid, Niacin Supplement,
Organic Dried Kelp, d-Calcium Pantothenate, Riboflavin Supplement, Biotin, Vitamin B12 Supplement, Thiamine Mononitrate, Vitamin A Acetate, Pyridoxine Hydrochloride, Citric Acid, Vitamin D3 Supplement, Folic Acid, Potassium Chloride, Iron Sulfate, Zinc Sulfate, Zinc Proteinate, Iron Proteinate, Copper Sulfate, Zinc Oxide, Manganese Sulfate, Manganese Proteinate, Copper Proteinate, Manganous Oxide, Selenium, Calcium Iodate. Fresh, clean water should be kept available to the dog at all times.

Source: http://www.regalpetfoods.com/grainfree.pdf