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Innovative Mixing Solutions Case Study: RAM Mixing of Compounded Pharmaceuticals
Compounded Pharmaceuticals
RAM Mix Test Results
9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32
MIX NUMBER
Summary:
All mixes were well under the FDA required “readily mixed” RSD value line of 4% -- RSD results typically less than 3% Thorough mixing of various excipients and actives resulted from short mixing times in the RAM mixer – typically 2 to 4 minutes RAM mixing out performs all conventional pharmaceutical mixing processes
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RAM has demonstrated substantial value-add for mixing pharmaceutical powder products
Note: Values in the graph are color coded to correspond with the materials on the reverse side.
130 North Main Street, Suite 630 - Butte, MT USA 59701 1.406.497.5333 (p) / 1.406.497.5206 (f)
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Case Study (Continued): RAM Mixing of
Compounded Pharmaceuticals
Compounded Pharmaceuticals
Acceleration Time
Active Ingredient
Excipient
Progesterone
Lactose Monohydrate/Methocel E4M
Progesterone
Lactose Monohydrate/Methocel E4M
Domperidone
Domperidone
Methylprednisolone
Methylprednisolone
Testosterone
Lactose Monohydrate/Methocel E4M
Testosterone
Lactose Monohydrate/Methocel E4M
Budesonide
Avicel/Methocel E4M
Budesonide
Avicel/Methocel E4M
Ergotamine Tartrate
Lactose Monohydrate
Ergotamine Tartrate
Lactose Monohydrate
Estriol/Estradiol (50%/50%)
Lactose Monohydrate/Methocel E4M
Estriol/Estradiol (50%/50%)
Lactose Monohydrate/Methocel E4M
Levothyroxine Sodium
Avicel/Methocel E4M 35
Levothyroxine Sodium
Avicel/Methocel E4M 35
Levothyroxine Sodium
Avicel/Methocel E4M
Levothyroxine Sodium
Avicel/Methocel E4M
Liothyronine (T3)
Avicel/Methocel E4M
Liothyronine (T3)
Avicel/Methocel E4M
Liothyronine (T3)
Avicel/Methocel E4M
Liothyronine (T3)
Avicel/Methocel E4M
Domperidone 10mg Capsule (lactose):
Lactose Monohydrate
Domperidone 10mg Capsule (lactose):
Lactose Monohydrate
Domperidone 10mg Capsule (corn starch):
Corn Starch
Domperidone 10mg Capsule (corn starch):
Corn Starch
Domperidone 10mg Capsule (acidophilus):
Acidophilus
Domperidone 10mg Capsule (acidophilus):
Acidophilus
Domperidone 10mg Capsule (Loxasperse):
Loxasperse
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Domperidone 10mg Capsule (Loxasperse):
Loxasperse
Domperidone 10mg Capsule (Bimuno):
Domperidone 10mg Capsule (Bimuno):
130 North Main Street, Suite 630 - Butte, MT USA 59701 1.406.497.5333 (p) / 1.406.497.5206 (f)
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Source: http://www.resodynmixers.com/wp-content/uploads/2013/08/Pharmaceutical-Mixing-Case-Study.pdf
Comparison of immunomagnetic separation and cultural methods in detection of Escherichia coli O157 over two-year period S. Vidovic1, J. J. Germida2, and D. R. Korber1 Applied Microbiology and Food Science1, Soil Science2, University of Saskatchewan, Canada 3. Cultural method 4. Sensitivity of enrichment broths Detection of E.coli O157 by
Opinion Commentary 4 A newspaper with issues LETTERS TO THE EDITOR PUBLISHER Send comments to editor@smdp.com David Pisarra Send comments to editor@smdp.com No endorsement here EDITOR IN CHIEF Recently representatives from the Santa Monica He’s favoring the MANAGING EDITOR Red Cross chapter had the opportunity to meet withthe proponents of Proposition T, known a
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Innovative Mixing Solutions 
Case Study (Continued): RAM Mixing of