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Junior Tablets (62.5/25)
(Atovaquone and Proguanil Hydrochloride)
Consumer Medicine Information
you are taking any medicines containing
Do not stop taking Malarone, or change the
warfarin, rifampicin, rifabutin,
dose without first checking with your doctor.
Unless explained differently, the information for
tetracycline, metoclopramide or indinavir.
"Malarone" in this leaflet applies to both
you are taking any other medicines,
Malarone Tablets (250/100) and Malarone Junior
Malarone is not recommended for the treatment
including medicines you buy without a
Tablets (62.5/25) (refer to the "Product
of malaria in children less than 3 years of age.
description" section near the end of the leaflet fora description of these two products).
you are breastfeeding, pregnant or trying
to become pregnant.
Please read this leaflet carefully before you take
Immediately telephone your doctor or Poisons
This leaflet answers some common questions
Information Centre (telephone 131126) for
about Malarone. It does not contain all of the
advice, if you think you or anyone else may
Take Malarone as directed by your doctor or
have taken too much Malarone, even if there
It does not take the place of talking to your doctor
are no signs of discomfort or poisoning.
Prevention of malaria:
If you are not sure what to do, contact your
All medicines have risks and benefits. Your
doctor or pharmacist.
doctor has weighed the expected benefits of you
One Malarone Tablet (250/100) daily.
taking Malarone against the risks this medicine
Children (11-40 Kg):
Depending on the child's weight, one, two or
If you have any concerns about taking this
medicine, ask your doctor or pharmacist.
daily. For children over 40 kg in weight, one
Tell your doctor if, for any reason, you have
Keep this leaflet with the medicine.
Malarone Tablet (250/100) once a day. Your
not taken your medicine exactly as directed.
doctor will choose the right dose for the
If you forget to take a dose, take another as
soon as possible. Then go on as before.
In order to prevent malaria, it is important
Otherwise, your doctor may think that it was not
that you take your Malarone every day. Start
working as it should and change your treatment
Malarone belongs to a broad group of medicines
taking it 1 or 2 days before travelling to a
country (or countries) where you are at risk
It contains in one tablet a mixture of two
of getting malaria. Continue daily dosing
Do not give this medicine to anyone else, even
antimalarial medicines which work well when
if their symptoms seem similar to yours.
taken together. One medicine is atovaquone and
the other is proguanil hydrochloride.
Whilst in a malarious area, use of personal
Do not use Malarone to treat any other
protection such as permethrin impregnated
complaints unless your doctor says to.
Malarone is used to prevent or treat the type of
bed nets and topical insect repellents is also
falciparum malaria. Plasmodium falciparum
Be careful driving or operating machinery
belongs to one particular family of malaria
Treatment of malaria:
until you know how Malarone affects you.
parasites. It affects the blood and liver. Malarone
Malarone generally does not cause any
problems with your ability to drive a car or
Children (11-40 Kg):
Depending on the child's weight, one, two orthree Malarone Tablets (250/100) once a day,
for three days. For children over 40 kg in
Check with your doctor as soon as possible if
you think you are experiencing any side effects
once a day for three days. Your doctor will
you have ever had an allergic reaction to
or allergic reactions due to taking Malarone,
choose the right dose for the child.
even if the problem is not listed below.
Like other medicines, Malarone can cause some
ingredients listed at the end of this leaflet
side effects. If they occur, they are most likely to
Swallow each tablet whole. Malarone works
be minor and temporary. However, some may be
better if you take it with food or a milky drink
the expiry date (EXP) printed on the pack
and at about the same time each day.
The following side-effects have been reported in
For children who find the tablet(s) difficult to
persons taking Malarone or the active ingredients
the packaging is torn or shows signs of
swallow, they may be crushed and added to a
(atovaquone or proguanil). Most of these have
small amount of milk, just before being taken.
If you vomit within one hour of taking Malarone
Loss of appetite, feeling sick (nausea) and/or
take another dose as soon as you can. In the event
of diarrhoea, normal dosing should be continued
you are allergic to foods, dyes,
preservatives or any other medicines.
in the past Malarone has been ineffective
Headache, difficulty in sleeping, vivid or
Prevention of malaria:
after taking Malarone, your symptoms of
Malarone should be taken 1 or 2 days before
malaria have returned after improving for
travelling to a country (countries) where you are
at risk of getting malaria, and continued daily
Inflammation of the liver (hepatitis), yellow
you have diarrhoea (loose bowel motions).
while you are there and for 7 days after leaving.
discolouration of the skin or eyes (jaundice)
This may interfere with the absorption of
Treatment of malaria:
Malarone should be taken for three days in a row.
you have kidney problems.
Inflammation of blood vessels (vasculitis)
which may be visible as red or purple raised
spots on the skin, but can affect other parts of
active ingredients, atovaquone 250 mg and
Malarone Junior Tablets (62.5/25) contain
the active ingredients, atovaquone 62.5 mg
Skin rash, which may blister and looks like
small targets (central dark spots, surrounded
by paler area with a dark ring around the
Widespread rash with blisters and peeling
If you notice any of these symptoms contact
Seeing or hearing things that are not there(hallucinations).
Sometimes Malarone is associated with abnormal
blood tests of liver function. If this does happen it
is most likely a temporary change, as blood tests
of liver function become normal after completing
GlaxoSmithKline Australia Pty Ltd
A reduction in the number of red blood cells
Where to go for further information
(anaemia), white blood cells (neutropenia), orplatelets (cells necessary for blood clotting).
Pharmaceutical companies are not in a position to
give people an individual diagnosis or medical
An increase in amylase, which is an enzyme
advice. Your doctor or pharmacist is the best
person to give you advice on the treatment of
your condition. You may also be able to find
STOP taking Malarone and seek medical
general information about your disease and its
attention immediately if you experience any of
treatment from books, for example in public
the following severe allergy symptoms after
taking Malarone. Although they are rare,
these symptoms could be serious:
Sudden wheezing, tightness of the chest or
The information provided applies only to:
Swollen eyelids, face, lips, tongue or other
Malarone® is a registered trade mark of the
This is not a complete list of all possible side
effects. Others may occur in some people and
there may be some side effects not yet known.
Do not be alarmed by this list of possible side
effects. You may not experience any of them.
Keep this medicine where children cannot
reach it, such as in a locked cupboard.
Keep Malarone in a cool, dry place where it
stays below 30°C.
Do not leave in a car, on a window sill or in the
Keep Malarone in its blister pack until it is
time to take the tablets.
Return any unused or expired medicine to
Malarone Tablets (250/100) are round, pinkand film-coated, and are engraved with "GXCM3".
Malarone Tablets (250/100) are supplied inblister packs of 12 and 24 tablets.
Malarone Junior Tablets (62.5/25) are round,pink and film-coated, and are engraved with"GX CG7".
Malarone Junior Tablets (62.5/25) aresupplied in blister packs of 12 tablets.
Mr Ken Stewart Consultant Plastic Surgeon Workplaces Royal Hospital Sick Children, Edinburgh, EH9 1LF St John’s Hospital Livingston, EH54 6PP Appointments Consultant Plastic Surgeon and Lead Clinician Lothian University Hospitals Honorary Senior Lecturer University of Edinburgh Consultant Plastic Spire Murrayfield Hospital Qualifications Research Degrees B Med Biol w
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