Tablets (250/100)
Junior Tablets (62.5/25)

(Atovaquone and Proguanil Hydrochloride) Consumer Medicine Information
you are taking any medicines containing
Do not stop taking Malarone, or change the
warfarin, rifampicin, rifabutin,
dose without first checking with your doctor.
Unless explained differently, the information for tetracycline, metoclopramide or indinavir.
"Malarone" in this leaflet applies to both you are taking any other medicines,
Malarone Tablets (250/100) and Malarone Junior Malarone is not recommended for the treatment including medicines you buy without a
Tablets (62.5/25) (refer to the "Product of malaria in children less than 3 years of age.
description" section near the end of the leaflet fora description of these two products).
you are breastfeeding, pregnant or trying
to become pregnant.
Please read this leaflet carefully before you take Immediately telephone your doctor or Poisons
This leaflet answers some common questions Information Centre (telephone 131126) for
about Malarone. It does not contain all of the advice, if you think you or anyone else may
Take Malarone as directed by your doctor or have taken too much Malarone, even if there
It does not take the place of talking to your doctor are no signs of discomfort or poisoning.
Prevention of malaria:
If you are not sure what to do, contact your
All medicines have risks and benefits. Your doctor or pharmacist.
doctor has weighed the expected benefits of you One Malarone Tablet (250/100) daily.
taking Malarone against the risks this medicine Children (11-40 Kg):
Depending on the child's weight, one, two or
If you have any concerns about taking this
medicine, ask your doctor or pharmacist.
daily. For children over 40 kg in weight, one Tell your doctor if, for any reason, you have
Keep this leaflet with the medicine.
Malarone Tablet (250/100) once a day. Your not taken your medicine exactly as directed.
doctor will choose the right dose for the If you forget to take a dose, take another as
soon as possible. Then go on as before.
In order to prevent malaria, it is important Otherwise, your doctor may think that it was not that you take your Malarone every day. Start working as it should and change your treatment Malarone belongs to a broad group of medicines taking it 1 or 2 days before travelling to a country (or countries) where you are at risk It contains in one tablet a mixture of two of getting malaria. Continue daily dosing Do not give this medicine to anyone else, even
antimalarial medicines which work well when if their symptoms seem similar to yours.
taken together. One medicine is atovaquone and the other is proguanil hydrochloride.
Whilst in a malarious area, use of personal Do not use Malarone to treat any other
protection such as permethrin impregnated complaints unless your doctor says to.
Malarone is used to prevent or treat the type of bed nets and topical insect repellents is also falciparum malaria. Plasmodium falciparum Be careful driving or operating machinery
belongs to one particular family of malaria Treatment of malaria:
until you know how Malarone affects you.
parasites. It affects the blood and liver. Malarone Malarone generally does not cause any
problems with your ability to drive a car or
operate machinery.
Children (11-40 Kg):
Depending on the child's weight, one, two orthree Malarone Tablets (250/100) once a day, for three days. For children over 40 kg in Check with your doctor as soon as possible if
you think you are experiencing any side effects
once a day for three days. Your doctor will you have ever had an allergic reaction to or allergic reactions due to taking Malarone,
choose the right dose for the child.
even if the problem is not listed below.
Like other medicines, Malarone can cause some ingredients listed at the end of this leaflet side effects. If they occur, they are most likely to Swallow each tablet whole. Malarone works be minor and temporary. However, some may be better if you take it with food or a milky drink the expiry date (EXP) printed on the pack
and at about the same time each day.
has passed.
The following side-effects have been reported in For children who find the tablet(s) difficult to persons taking Malarone or the active ingredients the packaging is torn or shows signs of
swallow, they may be crushed and added to a (atovaquone or proguanil). Most of these have tampering
small amount of milk, just before being taken.
If you vomit within one hour of taking Malarone Loss of appetite, feeling sick (nausea) and/or take another dose as soon as you can. In the event of diarrhoea, normal dosing should be continued you are allergic to foods, dyes,
preservatives or any other medicines.
in the past Malarone has been ineffective
Headache, difficulty in sleeping, vivid or Prevention of malaria:
after taking Malarone, your symptoms of
Malarone should be taken 1 or 2 days before malaria have returned after improving for
travelling to a country (countries) where you are at risk of getting malaria, and continued daily Inflammation of the liver (hepatitis), yellow you have diarrhoea (loose bowel motions).
while you are there and for 7 days after leaving.
discolouration of the skin or eyes (jaundice) This may interfere with the absorption of
Treatment of malaria:
Malarone should be taken for three days in a row.
you have kidney problems.
Inflammation of blood vessels (vasculitis) which may be visible as red or purple raised spots on the skin, but can affect other parts of active ingredients, atovaquone 250 mg and Malarone Junior Tablets (62.5/25) contain the active ingredients, atovaquone 62.5 mg Skin rash, which may blister and looks like small targets (central dark spots, surrounded by paler area with a dark ring around the Widespread rash with blisters and peeling If you notice any of these symptoms contact Seeing or hearing things that are not there(hallucinations).
Sometimes Malarone is associated with abnormal blood tests of liver function. If this does happen it is most likely a temporary change, as blood tests of liver function become normal after completing GlaxoSmithKline Australia Pty Ltd
A reduction in the number of red blood cells Where to go for further information (anaemia), white blood cells (neutropenia), orplatelets (cells necessary for blood clotting).
Pharmaceutical companies are not in a position to give people an individual diagnosis or medical An increase in amylase, which is an enzyme advice. Your doctor or pharmacist is the best person to give you advice on the treatment of your condition. You may also be able to find STOP taking Malarone and seek medical
general information about your disease and its attention immediately if you experience any of
treatment from books, for example in public the following severe allergy symptoms after
taking Malarone. Although they are rare,
these symptoms could be serious:
Sudden wheezing, tightness of the chest or The information provided applies only to: Swollen eyelids, face, lips, tongue or other Malarone® is a registered trade mark of the This is not a complete list of all possible side effects. Others may occur in some people and there may be some side effects not yet known.
Do not be alarmed by this list of possible side
effects. You may not experience any of them.
Keep this medicine where children cannot
reach it, such as in a locked cupboard.

Keep Malarone in a cool, dry place where it
stays below 30°C.

Do not leave in a car, on a window sill or in the

Keep Malarone in its blister pack until it is
time to take the tablets.

Return any unused or expired medicine to
your pharmacist.

Malarone Tablets (250/100) are round, pinkand film-coated, and are engraved with "GXCM3".
Malarone Tablets (250/100) are supplied inblister packs of 12 and 24 tablets.
Malarone Junior Tablets (62.5/25) are round,pink and film-coated, and are engraved with"GX CG7".
Malarone Junior Tablets (62.5/25) aresupplied in blister packs of 12 tablets.


Dr francoise firmin

Mr Ken Stewart Consultant Plastic Surgeon Workplaces Royal Hospital Sick Children, Edinburgh, EH9 1LF St John’s Hospital Livingston, EH54 6PP Appointments Consultant Plastic Surgeon and Lead Clinician Lothian University Hospitals Honorary Senior Lecturer University of Edinburgh Consultant Plastic Spire Murrayfield Hospital Qualifications Research Degrees B Med Biol w


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