AMERICAN ACADEMY OF PEDIATRICS
Organizational Principles to Guide and Define the Child Health Care System and/or Improve the Health of All Children
Breastfeeding and the Use of Human Milk
Considerable advances have occurred in
tions are consistent with the goals and objectives of
recent years in the scientific knowledge of the benefits of
Healthy People 2010
,4 the Department of Health and
breastfeeding, the mechanisms underlying these bene-
Human Services’ HHS Blueprint for Action on Breastfeed-
fits, and in the clinical management of breastfeeding.
,5 and the United States Breastfeeding Committee’s
This policy statement on breastfeeding replaces the 1997
Breastfeeding in the United States: A National Agenda
policy statement of the American Academy of Pediatrics
This statement provides the foundation for issues
and reflects this newer knowledge and the supporting
publications. The benefits of breastfeeding for the in-
related to breastfeeding and lactation management
fant, the mother, and the community are summarized,
for other AAP publications including the New Moth-
and recommendations to guide the pediatrician and other
er’s Guide to Breastfeeding
7 and chapters dealing with
health care professionals in assisting mothers in the ini-
breastfeeding in the AAP/American College of Ob-
tiation and maintenance of breastfeeding for healthy
stetricians and Gynecologists Guidelines for Perinatal
term infants and high-risk infants are presented. The
,8 the Pediatric Nutrition Handbook
,9 the Red
policy statement delineates various ways in which pedi-
,10 and the Handbook of Pediatric Environmental
atricians can promote, protect, and support breastfeeding
not only in their individual practices but also in the
hospital, medical school, community, and nation. Pedi-
atrics 2005;115:496–506; breast, breastfeeding, breast milk,
human milk, lactation.
Child Health Benefits
Human milk is species-specific, and all substitute
feeding preparations differ markedly from it, making
ABBREVIATIONS. AAP, American Academy of Pediatrics; WIC,Supplemental Nutrition Program for Women, Infants, and Children;
human milk uniquely superior for infant feeding.12
CMV, cytomegalovirus; G6PD, glucose-6-phosphate dehydrogenase.
Exclusive breastfeeding is the reference or normativemodel against which all alternative feeding methods
must be measured with regard to growth, health,
Extensive research using improved epidemio- development,andallothershort-andlong-termout-
logic methods and modern laboratory tech-
comes. In addition, human milk-fed premature in-
niques documents diverse and compelling ad-
fants receive significant benefits with respect to host
vantages for infants, mothers, families, and society
protection and improved developmental outcomes
from breastfeeding and use of human milk for infant
compared with formula-fed premature infants.13–22
feeding.1 These advantages include health, nutri-
From studies in preterm and term infants, the fol-
tional, immunologic, developmental, psychologic,
lowing outcomes have been documented.
social, economic, and environmental benefits. In1997, the American Academy of Pediatrics (AAP)
published the policy statement Breastfeeding and the
Research in developed and developing countries
Use of Human Milk
.2 Since then, significant advances
of the world, including middle-class populations in
in science and clinical medicine have occurred. This
developed countries, provides strong evidence that
revision cites substantial new research on the impor-
human milk feeding decreases the incidence and/or
tance of breastfeeding and sets forth principles to
severity of a wide range of infectious diseases23 in-
guide pediatricians and other health care profession-
cluding bacterial meningitis,24,25 bacteremia,25,26 di-
als in assisting women and children in the initiation
arrhea,27–33 respiratory tract infection,22,33–40 necro-
and maintenance of breastfeeding. The ways pedia-
tizing enterocolitis,20,21 otitis media,27,41–45 urinary
tricians can protect, promote, and support breast-
tract infection,46,47 and late-onset sepsis in preterm
feeding in their individual practices, hospitals, med-
infants.17,20 In addition, postneonatal infant mortal-
ical schools, and communities are delineated, and the
ity rates in the United States are reduced by 21% in
central role of the pediatrician in coordinating breast-
feeding management and providing a medical homefor the child is emphasized.3 These recommenda-
Some studies suggest decreased rates of sudden
infant death syndrome in the first year of life49–55 and
doi:10.1542/peds.2004-2491PEDIATRICS (ISSN 0031 4005). Copyright 2005 by the American Acad-
reduction in incidence of insulin-dependent (type 1)
and non–insulin-dependent (type 2) diabetes melli-
tus,56–59 lymphoma, leukemia, and Hodgkin dis-
mothers who are using drugs of abuse (“street
ease,60–62 overweight and obesity,19,63–70 hypercho-
drugs”); and mothers who have herpes simplex le-
lesterolemia,71 and asthma36–39 in older children and
sions on a breast (infant may feed from other breast
adults who were breastfed, compared with individ-
if clear of lesions). Appropriate information about
uals who were not breastfed. Additional research in
infection-control measures should be provided to
In the United States, mothers who are infected
with human immunodeficiency virus (HIV) have
Breastfeeding has been associated with slightly en-
been advised not to breastfeed their infants.112 In
hanced performance on tests of cognitive develop-
developing areas of the world with populations at
ment.14,15,72–80 Breastfeeding during a painful proce-
increased risk of other infectious diseases and nutri-
dure such as a heel-stick for newborn screening
tional deficiencies resulting in increased infant death
rates, the mortality risks associated with artificialfeeding may outweigh the possible risks of acquiring
Maternal Health Benefits
HIV infection.113,114 One study in Africa detailed in 2
Important health benefits of breastfeeding and lac-
reports115,116 found that exclusive breastfeeding for
tation are also described for mothers.83 The benefits
the first 3 to 6 months after birth by HIV-infected
include decreased postpartum bleeding and more
mothers did not increase the risk of HIV transmis-
rapid uterine involution attributable to increased
sion to the infant, whereas infants who received
concentrations of oxytocin,84 decreased menstrual
mixed feedings (breastfeeding with other foods or
blood loss and increased child spacing attributable to
milks) had a higher rate of HIV infection compared
lactational amenorrhea,85 earlier return to prepreg-
with infants who were exclusively formula-fed.
nancy weight,86 decreased risk of breast cancer,87–92
Women in the United States who are HIV-positive
decreased risk of ovarian cancer,93 and possibly de-
should not breastfeed their offspring. Additional
creased risk of hip fractures and osteoporosis in the
studies are needed before considering a change from
CONDITIONS THAT ARE NOT
In addition to specific health advantages for in-
CONTRAINDICATIONS TO BREASTFEEDING
fants and mothers, economic, family, and environ-
Certain conditions have been shown to be compat-
mental benefits have been described. These benefits
ible with breastfeeding. Breastfeeding is not contra-
include the potential for decreased annual health
indicated for infants born to mothers who are hepa-
care costs of $3.6 billion in the United States97,98; de-
titis B surface antigen–positive,111 mothers who are
creased costs for public health programs such as the
infected with hepatitis C virus (persons with hepati-
Special Supplemental Nutrition Program for Women,
tis C virus antibody or hepatitis C virus-RNA–posi-
Infants, and Children (WIC)99; decreased parental em-
tive blood),111 mothers who are febrile (unless cause
ployee absenteeism and associated loss of family in-
is a contraindication outlined in the previous sec-
come; more time for attention to siblings and other
tion),117 mothers who have been exposed to low-
family matters as a result of decreased infant illness;
level environmental chemical agents,118,119 and
decreased environmental burden for disposal of for-
mothers who are seropositive carriers of cytomega-
mula cans and bottles; and decreased energy demands
lovirus (CMV) (not recent converters if the infant is
for production and transport of artificial feeding prod-
term).111 Decisions about breastfeeding of very low
ucts.100–102 These savings for the country and for fam-
birth weight infants (birth weight Ͻ1500 g) by moth-
ilies would be offset to some unknown extent by in-
ers known to be CMV-seropositive should be made
creased costs for physician and lactation consultations,
with consideration of the potential benefits of human
increased office-visit time, and cost of breast pumps
milk versus the risk of CMV transmission.120,121
and other equipment, all of which should be covered
Freezing and pasteurization can significantly de-
by insurance payments to providers and families.
Tobacco smoking by mothers is not a contraindi-
CONTRAINDICATIONS TO BREASTFEEDING
cation to breastfeeding, but health care professionals
Although breastfeeding is optimal for infants,
should advise all tobacco-using mothers to avoid
there are a few conditions under which breastfeeding
smoking within the home and to make every effort to
may not be in the best interest of the infant. Breast-
wean themselves from tobacco as rapidly as possi-
feeding is contraindicated in infants with classic
galactosemia (galactose 1-phosphate uridyltrans-
Breastfeeding mothers should avoid the use of
ferase deficiency)103; mothers who have active un-
alcoholic beverages, because alcohol is concentrated
treated tuberculosis disease or are human T-cell lym-
in breast milk and its use can inhibit milk produc-
photropic virus type I– or II–positive104,105; mothers
tion. An occasional celebratory single, small alcoholic
who are receiving diagnostic or therapeutic radioac-
drink is acceptable, but breastfeeding should be
tive isotopes or have had exposure to radioactive
materials (for as long as there is radioactivity in the
For the great majority of newborns with jaundice
milk)106–108; mothers who are receiving antimetabo-
and hyperbilirubinemia, breastfeeding can and
lites or chemotherapeutic agents or a small number
should be continued without interruption. In rare
of other medications until they clear the milk109,110;
instances of severe hyperbilirubinemia, breastfeed-
Breastfeeding Rates for Infants in the United States: Any (Exclusive)
NA indicates that the data are not available.
ing may need to be interrupted temporarily for a
lack of guidance and encouragement from health
Data indicate that the rate of initiation and dura-
RECOMMENDATIONS ON BREASTFEEDING FOR
tion of breastfeeding in the United States are well
HEALTHY TERM INFANTS
below the Healthy People 2010
goals (see Table 1).4,125
1. Pediatricians and other health care professionals
Furthermore, many of the mothers counted as breast-
should recommend human milk for all infants in
feeding were supplementing their infants with for-
whom breastfeeding is not specifically contrain-
mula during the first 6 months of the infant’s life.5,126
dicated and provide parents with complete, cur-
Although breastfeeding initiation rates have in-
rent information on the benefits and techniques
creased steadily since 1990, exclusive breastfeeding
of breastfeeding to ensure that their feeding de-
initiation rates have shown little or no increase over
that same period of time. Similarly, 6 months after
• When direct breastfeeding is not possible, ex-
birth, the proportion of infants who are exclusively
breastfed has increased at a much slower rate than
ed.150,151 If a known contraindication to breast-
that of infants who receive mixed feedings.125 The
feeding is identified, consider whether the
AAP Section on Breastfeeding, American College of
contraindication may be temporary, and if so,
Obstetricians and Gynecologists, American Acad-
advise pumping to maintain milk production.
emy of Family Physicians, Academy of Breastfeeding
Before advising against breastfeeding or rec-
Medicine, World Health Organization, United Na-
tions Children’s Fund, and many other health orga-
benefits of breastfeeding against the risks of
nizations recommend exclusive breastfeeding for the
first 6 months of life.‡2,127–130 Exclusive breastfeeding
2. Peripartum policies and practices that optimize
is defined as an infant’s consumption of human milk
breastfeeding initiation and maintenance should
with no supplementation of any type (no water, no
juice, no nonhuman milk, and no foods) except for
• Education of both parents before and after
vitamins, minerals, and medications.131 Exclusive
delivery of the infant is an essential compo-
breastfeeding has been shown to provide improved
nent of successful breastfeeding. Support and
protection against many diseases and to increase the
encouragement by the father can greatly assist
likelihood of continued breastfeeding for at least the
the mother during the initiation process and
Obstacles to initiation and continuation of breast-
arise. Consistent with appropriate care for the
feeding include insufficient prenatal education about
mother, minimize or modify the course of ma-
breastfeeding132,133; disruptive hospital policies and
ternal medications that have the potential for
practices134; inappropriate interruption of breast-
altering the infant’s alertness and feeding be-
feeding135; early hospital discharge in some popula-
havior.152,153 Avoid procedures that may inter-
tions136; lack of timely routine follow-up care and
fere with breastfeeding or that may traumatize
postpartum home health visits137; maternal employ-
the infant, including unnecessary, excessive, and
ment138,139 (especially in the absence of workplace
overvigorous suctioning of the oral cavity,
facilities and support for breastfeeding)140; lack of
esophagus, and airways to avoid oropharyngeal
family and broad societal support141; media por-
mucosal injury that may lead to aversive feeding
trayal of bottle feeding as normative142; commercial
promotion of infant formula through distribution of
3. Healthy infants should be placed and remain in
hospital discharge packs, coupons for free or dis-
direct skin-to-skin contact with their mothers im-
counted formula, and some television and general
mediately after delivery until the first feeding is
magazine advertising143,144; misinformation; and
accomplished.156–158• The alert, healthy newborn infant is capable of
latching on to a breast without specific assis-
‡ There is a difference of opinion among AAP experts on this matter. The
tance within the first hour after birth.156 Dry
Section on Breastfeeding acknowledges that the Committee on Nutritionsupports introduction of complementary foods between 4 and 6 months of
the infant, assign Apgar scores, and perform
age when safe and nutritious complementary foods are available.
the initial physical assessment while the infant
is with the mother. The mother is an optimal
clearly communicated to both parents and to
heat source for the infant.159,160 Delay weigh-
ing, measuring, bathing, needle-sticks, and
8. All breastfeeding newborn infants should be
eye prophylaxis until after the first feeding is
seen by a pediatrician or other knowledgeable and
completed. Infants affected by maternal med-
experienced health care professional at 3 to 5 days
ications may require assistance for effective
of age as recommended by the AAP.124,176,177
latch-on.156 Except under unusual circum-
• This visit should include infant weight; phys-
stances, the newborn infant should remain
ical examination, especially for jaundice and
with the mother throughout the recovery pe-
hydration; maternal history of breast problems
(painful feedings, engorgement); infant elimi-
4. Supplements (water, glucose water, formula, and
nation patterns (expect 3–5 urines and 3– 4
other fluids) should not be given to breastfeeding
stools per day by 3–5 days of age; 4 – 6 urines
newborn infants unless ordered by a physician
and 3– 6 stools per day by 5–7 days of age);
when a medical indication exists.148,162–165
and a formal, observed evaluation of breast-
5. Pacifier use is best avoided during the initiation
feeding, including position, latch, and milk
of breastfeeding and used only after breastfeed-
transfer. Weight loss in the infant of greater
than 7% from birth weight indicates possible
• In some infants early pacifier use may interfere
breastfeeding problems and requires more in-
with establishment of good breastfeeding prac-
tensive evaluation of breastfeeding and possi-
tices, whereas in others it may indicate the pres-
ble intervention to correct problems and im-
ence of a breastfeeding problem that requires
9. Breastfeeding infants should have a second am-
• This recommendation does not contraindicate
bulatory visit at 2 to 3 weeks of age so that the
pacifier use for nonnutritive sucking and oral
health care professional can monitor weight gain
training of premature infants and other special
and provide additional support and encourage-
ment to the mother during this critical period.
6. During the early weeks of breastfeeding, moth-
10. Pediatricians and parents should be aware that
ers should be encouraged to have 8 to 12 feed-
exclusive breastfeeding is sufficient to supportoptimal growth and development for approxi-
ings at the breast every 24 hours, offering the
mately the first 6 months of life‡ and provides
breast whenever the infant shows early signs of
continuing protection against diarrhea and respi-
hunger such as increased alertness, physical ac-
ratory tract infection.30,34,128,178–184 Breastfeeding
should be continued for at least the first year of
• Crying is a late indicator of hunger.171 Appro-
life and beyond for as long as mutually desired
priate initiation of breastfeeding is facilitated
by continuous rooming-in throughout the day
• Complementary foods rich in iron should be
and night.172 The mother should offer both
breasts at each feeding for as long a period as
months of age.186–187 Preterm and low birth
the infant remains at the breast.173 At each
weight infants and infants with hematologic
feed the first breast offered should be alter-
disorders or infants who had inadequate iron
nated so that both breasts receive equal stim-
stores at birth generally require iron supple-
ulation and draining. In the early weeks after
mentation before 6 months of age.148,188–192
Iron may be administered while continuing
aroused to feed if 4 hours have elapsed since
• Unique needs or feeding behaviors of individ-
• After breastfeeding is well established, the fre-
ual infants may indicate a need for introduc-
quency of feeding may decline to approxi-
tion of complementary foods as early as 4
mately 8 times per 24 hours, but the infant
months of age, whereas other infants may not
may increase the frequency again with growth
be ready to accept other foods until approxi-
spurts or when an increase in milk volume is
• Introduction of complementary feedings be-
7. Formal evaluation of breastfeeding, including
fore 6 months of age generally does not in-
observation of position, latch, and milk transfer,
crease total caloric intake or rate of growth
should be undertaken by trained caregivers at least
and only substitutes foods that lack the pro-
twice daily and fully documented in the record
during each day in the hospital after birth.174,175
• During the first 6 months of age, even in hot
• Encouraging the mother to record the time
climates, water and juice are unnecessary for
and duration of each breastfeeding, as well as
breastfed infants and may introduce contami-
urine and stool output during the early days
of breastfeeding in the hospital and the first
• Increased duration of breastfeeding confers
weeks at home, helps to facilitate the evalua-
significant health and developmental benefits
tion process. Problems identified in the hospi-
for the child and the mother, especially in
tal should be addressed at that time, and a
delaying return of fertility (thereby promoting
• There is no upper limit to the duration of
feeding alternative for infants whose mothers are
breastfeeding and no evidence of psychologic
unable or unwilling to provide their own milk.
Human milk banks in North America adhere to
into the third year of life or longer.197
national guidelines for quality control of screening
• Infants weaned before 12 months of age
and testing of donors and pasteurize all milk be-
should not receive cow’s milk but should re-
fore distribution.206–208 Fresh human milk from
unscreened donors is not recommended because
11. All breastfed infants should receive 1.0 mg of
of the risk of transmission of infectious agents.
vitamin K1 oxide intramuscularly after the first
• Precautions should be followed for infants with
feeding is completed and within the first 6 hours
glucose-6-phosphate dehydrogenase (G6PD) defi-
ciency. G6PD deficiency has been associated with
• Oral vitamin K is not recommended. It may
an increased risk of hemolysis, hyperbiliru-
not provide the adequate stores of vitamin K
binemia, and kernicterus.209 Mothers who breast-
necessary to prevent hemorrhage later in in-
feed infants with known or suspected G6PD defi-
fancy in breastfed infants unless repeated
ciency should not ingest fava beans or medications
doses are administered during the first 4
such as nitrofurantoin, primaquine phosphate, or
phenazopyridine hydrochloride, which are known
12. All breastfed infants should receive 200 IU of
to induce hemolysis in deficient individuals.210,211
oral vitamin D drops daily beginning during thefirst 2 months of life and continuing until the
ROLE OF PEDIATRICIANS AND OTHER HEALTH
daily consumption of vitamin D-fortified for-
CARE PROFESSIONALS IN PROTECTING,
PROMOTING, AND SUPPORTING
• Although human milk contains small amounts
of vitamin D, it is not enough to prevent rick-
Many pediatricians and other health care profes-
ets. Exposure of the skin to ultraviolet B wave-
sionals have made great efforts in recent years to
lengths from sunlight is the usual mechanism
support and improve breastfeeding success by fol-
for production of vitamin D. However, signif-
lowing the principles and guidance provided by
icant risk of sunburn (short-term) and skin
the AAP,2 the American College of Obstetricians
cancer (long-term) attributable to sunlight ex-
and Gynecologists,127 the American Academy of
posure, especially in younger children, makes
Family Physicians,128 and many other organiza-
it prudent to counsel against exposure to sun-
tions.5,6,8,130,133,142,162 The following guidelines
light. Furthermore, sunscreen decreases vita-
summarize these concepts for providing an opti-
13. Supplementary fluoride should not be provided
• From 6 months to 3 years of age, the decision
• Promote, support, and protect breastfeeding en-
whether to provide fluoride supplementation
thusiastically. In consideration of the extensively
should be made on the basis of the fluoride
published evidence for improved health and de-
concentration in the water supply (fluoride
velopmental outcomes in breastfed infants and
supplementation generally is not needed un-
their mothers, a strong position on behalf of
less the concentration in the drinking water is
Ͻ0.3 ppm) and in other food, fluid sources,
• Promote breastfeeding as a cultural norm and en-
courage family and societal support for breast-
14. Mother and infant should sleep in proximity to
each other to facilitate breastfeeding.203
• Recognize the effect of cultural diversity on breast-
15. Should hospitalization of the breastfeeding
feeding attitudes and practices and encourage
mother or infant be necessary, every effort
variations, if appropriate, that effectively promote
should be made to maintain breastfeeding, pref-
and support breastfeeding in different cultures.
erably directly, or pumping the breasts and feed-
• Become knowledgeable and skilled in the physiol-
ogy and the current clinical management of breast-
ADDITIONAL RECOMMENDATIONS FOR
• Encourage development of formal training in
• Hospitals and physicians should recommend hu-
breastfeeding and lactation in medical schools, in
man milk for premature and other high-risk in-
residency and fellowship training programs, and
fants either by direct breastfeeding and/or using
the mother’s own expressed milk.13 Maternal sup-
• Use every opportunity to provide age-appropriate
port and education on breastfeeding and milk ex-
breastfeeding education to children and adults in
pression should be provided from the earliest pos-
the medical setting and in outreach programs for
sible time. Mother-infant skin-to-skin contact and
direct breastfeeding should be encouraged as earlyas feasible.204,205 Fortification of expressed human
milk is indicated for many very low birth weight
• Work collaboratively with the obstetric commu-
infants.13 Banked human milk may be a suitable
nity to ensure that women receive accurate and
sufficient information throughout the perinatal pe-
• Encourage employers to provide appropriate facil-
riod to make a fully informed decision about in-
ities and adequate time in the workplace for
breastfeeding and/or milk expression.
• Work collaboratively with the dental community
• Encourage child care providers to support breast-
to ensure that women are encouraged to continue
feeding and the use of expressed human milk pro-
to breastfeed and use good oral health practices.
Infants should receive an oral health-risk assess-
• Support the efforts of parents and the courts to
ment by the pediatrician between 6 months and 1
ensure continuation of breastfeeding in separation
year of age and/or referred to a dentist for evalu-
ation and treatment if at risk of dental caries or
• Provide counsel to adoptive mothers who decide
to breastfeed through induced lactation, a process
• Promote hospital policies and procedures that fa-
requiring professional support and encourage-
cilitate breastfeeding. Work actively toward elim-
inating hospital policies and practices that discour-
• Encourage development and approval of govern-
age breastfeeding (eg, promotion of infant formula
mental policies and legislation that are supportive
in hospitals including infant formula discharge
of a mother’s choice to breastfeed.
packs and formula discount coupons, separationof mother and infant, inappropriate infant feeding
images, and lack of adequate encouragement and
• Promote continued basic and clinical research in
support of breastfeeding by all health care staff).
the field of breastfeeding. Encourage investigators
Encourage hospitals to provide in-depth training
and funding agencies to pursue studies that fur-
in breastfeeding for all health care staff (including
ther delineate the scientific understandings of lac-
physicians) and have lactation experts available at
tation and breastfeeding that lead to improved
clinical practice in this medical field.216
• Provide effective breast pumps and private lacta-
tion areas for all breastfeeding mothers (patients
and staff) in ambulatory and inpatient areas of the
Although economic, cultural, and political pres-
sures often confound decisions about infant feeding,
• Develop office practices that promote and support
the AAP firmly adheres to the position that breast-
breastfeeding by using the guidelines and materi-
feeding ensures the best possible health as well as the
als provided by the AAP Breastfeeding Promotion
best developmental and psychosocial outcomes for
in Physicians’ Office Practices program.214
the infant. Enthusiastic support and involvement of
• Become familiar with local breastfeeding resources
pediatricians in the promotion and practice of breast-
(eg, WIC clinics, breastfeeding medical and nurs-
feeding is essential to the achievement of optimal
ing specialists, lactation educators and consult-
infant and child health, growth, and development.
ants, lay support groups, and breast-pump rentalstations) so that patients can be referred appropri-
ately.215 When specialized breastfeeding services
are used, the essential role of the pediatrician as
the infant’s primary health care professional
within the framework of the medical home needs
• Encourage adequate, routine insurance coverage
for necessary breastfeeding services and supplies,
including the time required by pediatricians and
other licensed health care professionals to assess
and manage breastfeeding and the cost for the
• Develop and maintain effective communication
and coordination with other health care profes-
sionals to ensure optimal breastfeeding education,
support, and counseling. AAP and WIC breast-
feeding coordinators can facilitate collaborative re-
lationships and develop programs in the commu-nity and in professional organizations for support
• Advise mothers to continue their breast self-exam-
inations on a monthly basis throughout lactationand to continue to have annual clinical breast ex-
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5 • CONTENUTO DEI FITOTERAPICI: POCHE CERTEZZE, RAGIONEVOLI DUBBI Albert Szent-Györgyi, premio Nobel nel 1937 per studi fondamen-tali sulla vitamina C, era solito ripetere che se si studiassero con mag-giore attenzione le sostanze che già abbiamo sugli scaffali delle farma-cie e/o dei laboratori si conseguirebbero probabilmente risultati più si-gnificativi e utili per l’uomo che
PRESCRIBING INFORMATION ©2011 GlaxoSmithKline Inc. All Rights Reserved ®K-10 is a registered trademark, used under license by GlaxoSmithKline Inc. PRESCRIBING INFORMATION NAME OF DRUG (Potassium Chloride Solution, 10%) THERAPEUTIC CLASSIFICATION INDICATIONS The prevention and treatment of hypokalemic states which may occur in conjunction with diuretic therapy, di