Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Microsoft word - rx tier groups 11-12-09.docm

2010 Three-Tier Prescription Drug Reference Guide Amoxicillin Trihydrate Capsule, Chewable Tablet, Drops, Suspension, Tablet Amoxicillin Trihydrate/ Potassium Clavulanate Chloromycetin Erythromycin Base Capsule, Delayed Release Erythromycin Base Tablet, Enteric-Coated 250, 333 Erythromycin Ethylsuccinate/ Sulfisoxazole Acetyl 2010 Three-Tier Prescription Drug Reference Guide Cardiovascular/Heart Disease Coagulation Therapy 2010 Three-Tier Prescription Drug Reference Guide Cardiovascular/Heart Disease High Blood Pressure Bisoprolol Fumarate/ Hydrochlorothiazide Dibenzyline 2010 Three-Tier Prescription Drug Reference Guide Cardiovascular/Heart Disease High Blood Pressure (continued from previous page) Nifedipine Tablet, Osmotic Laser-Drilled Cardiovascular/Heart Disease High Cholesterol 2010 Three-Tier Prescription Drug Reference Guide Central Nervous System Attention Deficit Disorder Sulfate/Dextroamphetamine Amphetamine Aspartate/Amphetamine Sulfate/Dextroamphetamine Capsule, Sustained-Release 24 Hour D-Amphetamine Sulfate Tablet, Capsule, Sustained-Action Methamphetamine HCI Tablet 2010 Three-Tier Prescription Drug Reference Guide Bupropion HCI Tablet, Sustained-Release 24 Hour Paroxetine HCI Sustained-Release, 24 Hour Acetaminophen/Caffeine/Butalbital Ergomar Alkaloids/Phenobarbital Ergotamine Tartrate/Caffeine Suppository, Rectal Ergotamine Tartrate/Caffeine/Belladonna Alkaloids/Pentobarbital Mucate/Acetaminophen/Dichloralphenazone Isometheptene/Acetaminophen/Caffeine 2010 Three-Tier Prescription Drug Reference Guide Central Nervous System Sedatives/Hypnotics Central Nervous System Seizure Disorders 2010 Three-Tier Prescription Drug Reference Guide 2010 Three-Tier Prescription Drug Reference Guide Alclometasone Dipropionate Cream, Ointment Betamethasone Dipropionate Cream, Lotion, Ointment Betamethasone Dipropionate/Propylene Glycol Gel, Lotion, Ointment Betamethasone DP Augmented Cream 0.05% Locoid Betamethasone Valerate Cream, Lotion, Ointment Clobetasol Propionate Cream, Gel, Ointment Sulfoxyl Clobetasol Propionate Solution, Non-Oral Trisoralen Clotrimazole/Betamethasone Dipropionate Zovirax Erythromycin Base/Ethyl Alcohol Swab, Medicated Fluocinolone Acetonide Solution Non-Oral Hydrocortisone Butyrate Ointment, Solution, Non- Oral Hydrocortisone Cream, Lotion, Ointment Mometasone Furoate Cream, Ointment, Solution 2010 Three-Tier Prescription Drug Reference Guide Dermatology (Continued from previous page) Sulfacetamide Sodium Suspension. Topical Triamcinolone Acetonide Cream, Lotion, Ointment Endocrine/Diabetes Blood Glucose Monitoring 2010 Three-Tier Prescription Drug Reference Guide Fortamet Tablet, Sr Osmotic Push 24 Hour 2010 Three-Tier Prescription Drug Reference Guide Methylprednisolone Tablet, Does Pack 4 mg Prednisolone Sodium Phosphate Solution, Oral 2010 Three-Tier Prescription Drug Reference Guide Neomycin Sulfate/Bacitracin Zinc Polymyxin B/ Hydrocortisone Ointment Neomycin Sulfate/Bacitracin/Polymyxin B Ointment Neomycin Sulfate/Dexamethasone Sodium Phosphate Neomycin Sulfate/Gramicidin D/Polymyxin B Sulfate/Hydrocortisone Suspension, Drops Neomycin/Polymyxin B Sulfate/Dexamethasone Sulfacetamide Sodium/Prednisolone Acetate Sulfacetamide Sodium/Prednisolone Sodium Acetazolamide Capsule, Sustained-Action Azopt 2010 Three-Tier Prescription Drug Reference Guide Prevacid Capsule, Delayed-Release Enteric-Coated Prevacid Suspension, Delayed Release, Reconst. Prochlorperazine Maleate 25 mg Suppository, 2010 Three-Tier Prescription Drug Reference Guide Promethazine/Codeine Neoral Tamoxifen Prograf 2010 Three-Tier Prescription Drug Reference Guide Acetaminophen/Phenyltoloxamine Citrate OxyContin Aspirin/Caffeine/Butalbital RMS-Suppository 10, 20, 30 mg Acetaminophen/Caffeine/Butalbital Codeine Phosphate/Aspirin/Caffeine/Butalbital Dihydrocodeine Bit/ Acetaminophen/Caffeine Hydrocodone Bit/Acetaminophen Elixir, Tablet 2010 Three-Tier Prescription Drug Reference Guide Musculoskeletal Pain Relief (continued from previous page) Morphine Sulfate Suppository, Rectal 5 mg Morphine Sulfate Tablet, Sustained-Action HCI/AcetaminophencetaminophenMusculoskelet Oxycodone HCI/Ibuprofen 2010 Three-Tier Prescription Drug Reference Guide Albuterol Sulfate/Ipratropium Solution, Non-Oral Cromolyn Sodium Ampul for Nebuization Pulmicort Isoetharine HCI Solution, Non-Oral T-Phyl 2010 Three-Tier Prescription Drug Reference Guide Maleate/Scopolamine Syrup Phenylephrine HCI/Phenylpropanolamine HCI/Phenyltoloxamine/Chlorpheniramine Phenylephrine HCI/Promethazine HCI Pseudoephedrine HCI/Brompheniramine Maleate Pseudoephedrine HCI/Chlorpheniramine Maleate Desogestrel-Ethinyl Estradiol/Ethinyl Estradiol Levonorgestrel-Ethinyl Estradiol Tablet, Dosepak, 3 month Medroxyprogesterone Acet 150 mg/ml Norethindrone A-E Estradiol/Ferrous Fumarate 2010 Three-Tier Prescription Drug Reference Guide Estradiol 1 mg/Norethindrone Acetate 0.5 mg Methyltestosterone/Estrogens, Esterified Tablet Prenatal Vitamins/Fe Asp Gly/Docusate/Folic Acid Prenatal Vitamins/Iron, Carbonyl/Docusate/Folic Acid Prenatal Vitamins/Vitamin A/Iron Fumarate/Folic 2010 Three-Tier Prescription Drug Reference Guide Additional Tier 3 Drugs with generic equivalent in Tier 1 Adderall (Amphetamine with Dextroamphetamine Salt Combination) Aldactone (Spironolactone) Augmentin ES (Amoxicillin with Potassium Clavulanate) Biaxin Tablet (Clarithromycin Tablet) Ritalin SR (Methylphenidate Extended-Release) Lamisil Tablet (Terbinafine Tablet) Sonata Lofibra (Fenofibrate Micronized) Tenoretic (Diltiazem Sustained-Release 24 Hour Capsule) Cleocin T (Clindamycin Gel, Lotion, Solution, Darvocet-N (Propoxyphene with Acetaminophen) Depakote (Divalproex Sodium Tablet, Enteric- Depo-Provera (Medroxyprogesterone Acetate 150 Ditropan XL (Oxybutynin Chloride Tablet, Diazide (Triamterene with Hydrochlorothiazide) Eskalith CR (Lithium Carbonate Controlled- Fioricet (Butalbital with Acetaminophen and Zovirax Capsule, Tablet, Suspension (Acyclovir)

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