CONTACT American College of Sports Medicine Why is Exercise Medicine? EXERCISE IS MEDICINE Physical inactivity is a fast-growing public health problem and contributes to a variety of chronic diseases and health complications, including obesity, heart disease, diabetes, hypertension, cancer, depression and anxiety, arthritis, and osteoporosis. In addition to improving a patient’s overall health, increasing physical activity has proven effective in the treatment and prevention of chronic diseases. Regular physical activity at the correct intensity:
• Reduces the risk of heart disease by 40%
• Reduces the incidence of high blood pressure, by almost 50% • Reduces the incidence of diabetes by almost 50%
Just 30 minutes of physical activity per day can:
• Reduce mortality and the risk of recurrent breast cancer by almost 50%
• Lower the risk of colon cancer by more than 60%
• Reduce the risk of developing of Alzheimer’s disease by one-third • Decrease depression as effectively as Prozac or behavioral therapy
PHYSICAL INACTIVITY LEADS TO HIGHER RISK OF DEATH
Physical inactivity has a greater effect on the rate of mortality than other major factors, such as smoking, hypertension, diabetes and high cholesterol.
Effect of Fitness (CRF*) on Mortality Attributable Fractions (%) for All-Cause Deaths 40,842 Men & 12,943 Women, ACLSBlair SN. Physical inactivity: the biggest public health problem of the 21st century. Br J Sports Med 2009; 43:1-2. CONTACT American College of Sports Medicine FIT VS. FAT — LEVEL OF FITNESS HAS GREATER EFFECT ON MORTALITY THAN BODY FAT
A low level of fitness is a bigger risk factor for mortality than mild-moderate obesity. It is better to be fit and overweight than unfit with a lower percentage of body fat.
Joint Associations of CRF* and % Body Fat with All-Cause Mortality, Adults 60+ Normal Obese
Rates adjusted for age, sex and exam year
PHYSICAL ACTIVITY DECREASES RISK FOR DIABETES PATIENTS WITH CARDIO VASCULAR DISEASE
Fitness levels have a substantial impact on the risk for cardio vascular disease mortality. Those with a moderate or high level of fitness are much less likely to die of cardio vascular disease than those who are less active.
CVD* Mortality Risk by Fitness and BMI Categories, 2316 Men with Diabetes, 179 CVD Deaths lity 8 rta 7 18.5 < BMI <25.0 25.0 ≤ BMI <30.0 30.0 ≤ BMI < 35.0
Rates adjusted for age, sex and exam year
Church TS et al. Arch Int Med 2005; 165:2114
Treatment If the patient is very symptomatic or has a very high blood glucose level, diet and lifestyle changes are unlikely to achieve target values. In this instance, pharmacological therapy should Algorithms showing the treatment of obese and non-obese individuals Sulphonylureas Traditionally, sulphonylureas have been regarded as the first-line drug treatment in type 2 diabetes
Course Information and Outline PHRM 409: Advanced Pharmaceutical Analysis [Credit: 4] Fall, 2012 Department of Pharmacy Instructor: Dr. Chowdhury Faiz Hossain, Professor and Dean, FSE. Section 2 Class Hours: 12:40 1:40 (Room-304) Course Objective: To give some ideas on advanced level about the principles and applications of NMR spectroscopy and Mass spect
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