Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Italcaffe.it

I T A L C A F F È C O F F E E H O U S E
A T H O M E O R A T W O R K
THE CAPSULES
With the ITALCAFFÈ ESPRESSO SYSTEM you can enjoy
the following products.

- A mix of exotic Arabic and
Robusta coffee flavours, carefully selected
and roasted just right to offer a creamy coffee
aroma with a sweet, robust flavour.
A
Italian-style
espresso
traditional form.

- A decaffeinated blend
with an extraordinary aroma. You won’t miss the
cream, body and aroma of the best espresso bar
coffees.

- It is the result of an
THE ESPRESSO MACHINES
accurate selection of the best varieties of the
Arabica species, known for its low caffeine con-
To get a good cup of coffee, a good blend is not
tent. Its pleasant rich and long-lasting aroma
enough. You also need the right equipment.
make it the favourite coffee of the real
connoisseur.
The capsule espresso machines Italcaffè Espresso
System is a first-class coffee maker that ensures a
top-quality Italian-style cup of espresso coffee,
and also allows you to enjoy other hot drinks de-
pending on your taste.

Capsule system advantages
Characteristics
Capsule characteristics: 6.8 grams of optimum
Automatic capsule brewing system
ground, measured and pressed coffee. Usage
simplicity:
Capsule holder
espresso coffee, even the inexperienced.
Used capsule removable container
Maximum cleanliness and hygiene: Once the
coffee is done, the capsule is collected into a
Equipped with a steam and hot water wand /
container and is ready for disposal without any
Optional
leftovers or residue; therefore, no waste.

Net weight: 5,0 kg

Italcaffè Espresso System is sealed quality.
Dimension: 32,0 x 26,0 x 24,0 cm
The innovative sealed capsules are individually
Container capacity: 2.0 litres
packaged
protected
preserve
just-roasted coffee freshness and aroma.
I T A L C A F F È S . P . A . - V i a G a l i l e o G a l i l e i 1 8 - 1 9 0 2 0 C e p a r a n a ( L a S p e z i a ) - I T A L I A
T e l. + 3 9 ( 0 1 8 7 ) 9 3 3 7 1 1 - F a x + 3 9 ( 0 1 8 7 ) 9 3 3 7 4 0 - S k y p e : i t a l c a f f e
E - M a i l i n f o @ i t a l c a f f e . i t - W e b h t t p : / / w w w . i t a l c a f f e . i t - h t t p : / / w w w . i t a l c a f f e . e u

Source: http://www.italcaffe.it/PDF/Capsules%20Brochure.pdf