Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Finalists_nej_2012

2012 FINALISTS
5th National Entertainment Journalism Awards
A - ENTERTAINMENT JOURNALIST OF THE YEAR, ALL PLATFORMS
* Gendy Alimurung, LA Weekly
* Jen Heger, RadarOnline
* Dylan Howard, Celebuzz
* Gary Lycan, Orange County Register
* Kim Masters, The Hollywood Reporter & KCRW

B. ANY MEDIA PLATFORM
B1 - BUSINESS
* Gendy Alimurung, LA Weekly, “The Death of Film”
* Leslie Bruce, The Hol ywood Reporter, “The Guilt and Glory of Housewives”
* Michael Calderone, Huffington Post Media Group, “NBC’s Olympic Trials: In Quest For
Ratings Gold, It Can’t Stumble”
* Kevin Ferguson, 89.3 KPCC, “Adult Film Industry Condom Law”
* Andy Fixmer & Edmund Lee, Bloomberg Businessweek, “Oprah’s OWN Loses Up to
$330 Mil ion Saddle Partner Discovery”
* Daniel Mil er, The Hol ywood Reporter, “Down the Rabbit Hole With Ron Tutor”
B2 - INVESTIGATIVE
* Jen Heger, RadarOnline, “Michael Jackson’s Fingerprints Not On Bottles of Drug That
Kil ed Him”
* John Horn, Nicole Sperling & Doug Smith, Los Angeles Times, “Unmasking the
Academy”
* Dylan Howard, Celebuzz, “Exposed: Hol ywood’s Clandestine & Il egal Poker Ring”
* Dylan Howard, Celebuzz, “Natalie Wood Drowning Probe Uncovers New Evidence”
* Daniel Miller, The Hol ywood Reporter, “Scientology’s Hol ywood Real Estate Empire”
B3 - MULTIMEDIA PACKAGE
* Juan Devis, Drew Tewksbury, Bruce Dickson & Justin Cram, KCET, “Artbound”
* Los Angeles Times Calendar, Film Data and Entertainment Online Web Team,
Los Angeles Times, “Inside the Academy”
* Steve Rowland, Steve Robinson, Tony Macaluso & Jon Tolansky, public radio
freelancer, “Shakespeare Moments: Globe to Globe”
* Michele Stueven, Dahvi Shira & Kris Widger, People.com, “Dancing With Stars Finale”
* Staff of The Hol ywood Reporter, “Rule Breakers 2011”
B4 - BROADCAST CRITIC
* John DeSando & Johnny DiLoretto, WCBE 90.5 FM, “Cinema Classics Co-Hosts”
* Joe Morgenstern, KCRW, “Film Reviews”
* Jackson Murphy, YNN-TV, “Lights-Camera-Jackson – Film Critic”
* Kenneth Turan, Katie McMurran, Brian Lauritzen & Gail Eichenthal, KUSC Radio,
“Kenneth Turan Film Critic, in Conversation”
C - BOOK
* Francine Brokaw, Sourced Media Books, Beyond the Red Carpet: The World of
Entertainment Journalists
* M.G. Lord, Walker/Bloomsbury, The Accidental Feminist: How Elizabeth Taylor
Raised Our Consciousness And We Were Too Distracted By Her Beauty To Notice
* Ruben V. Nepales, Anvil Publishing, Inc., My Filipino Connection: The Philippines in
Hol ywood
* Manny Pacheco (Introduction by Gary Lycan), Financial News and Talk AM 1510/
AM 1450, Son of Forgotten Hol ywood Forgotten History
D. PRINT – NEWSPAPERS OR MAGAZINES
D1 - NEWS, PRINT
* Gendy Alimurung, LA Weekly, “The Death of Film”
* Daniel e Berrin, The Jewish Journal of Greater Los Angeles, “Zionism and the Three
Picture Deal/Doing (Show) Business in Israel”
* Vickie Chang, OC Weekly, “His Goldenvoice”
* Dylan Howard, Celebuzz, “Hol ywood’s Clandestine & Il egal Poker Ring”
* Ken Lee, Jessica Herndon, Michele Stueven, Melody Chiu & Oliver Jones, People
Magazine, “Whitney Houston: A Tragic End”
D2 - PERSONALITY PROFILE, PRINT
* Gendy Alimurung, LA Weekly, “Never Grow Up”
* Greg Braxton, Los Angeles Times, “The Bailiff”
* Daniel Mil er & Matthew Bel oni, The Hol ywood Reporter, “The Nerd Who Burned
Hollywood”
* Dotson Rader & Maggie Murphy, Parade Magazine, “The Fantastic Mr. Fox”
* Stacey Wilson, The Hol ywood Reporter, “Conan O’Brien: End of the Pity Party”
D3 - FEATURE/SERIES, PRINT OVER 1,000 WORDS
* Candice Aman, Neon Tommy, “The Origami Vinyl Effect: How Record Stores are
Changing the Music Industry”
* Jenny Eliscu, The Hol ywood Reporter, “The Making of Baby Bieber”
* Katya Kazakina, Bloomberg Markets, “Picasso Reconsidered”
* Kim Masters & Daniel Mil er, The Hol ywood Reporter, “The Secret World of Hol ywood
Poker”
* Lavender Vroman, Antelope Val ey Press, “Acton’s Own ‘War Horse’”
* Stacey Wilson, The Hol ywood Reporter, “Conan O’Brien: End of the Pity Party”  
D4 - FEATURE - UNDER 1,000 WORDS
* Gendy Alimurung, LA Weekly, “Interview With A Corpse”
* Gary Baum, The Hol ywood Reporter, “The 3,000-Mile-Long Embrace”
* Matt Bel oni, Jay A. Fernandez, Daniel Mil er & Lacey Rose, The Hol ywood Reporter,
“Secrets of Hol ywood Agency Mailrooms”
* Marisa Laudadio, People Magazine, “Pink Rocks the Cradle”
* Elizabeth Leonard, People Magazine, “Kirstie Alley’s 100 lb. Slimdown!”  
D5 - CRITIC, PRINT
* Tim Goodman, The Hol ywood Reporter, “Assorted Reviews”
* Todd McCarthy, The Hol ywood Reporter, “Assorted Reviews”
* Mary McNamara, Los Angeles Times, “TV Columns”
* Randall Roberts, Los Angeles Times, “Music Reviews”
* Lavender Vroman, Antelope Val ey Press, "Assorted Reviews"
D6 - COLUMNIST, PRINT
* Gendy Alimurung, LA Weekly, “Candyland”
* Kathy Griffin, The Hol ywood Reporter, “Why You Should Stop Hiding Your Age”
* Gary Lycan, Orange County Register, “’Sweet Dick’ Whittington: An Unpredictable
Talent”
* Janet R. Nepales, Manila Bul etin, “Madonna Soaks Up With Writing - Directing Energy
Captures ‘W.E.’ Drama”
* Ruben V. Nepales, Philippine Daily Inquirer, “Childhood ‘Isolation’ Inspired His Passion”
D7 - ENTERTAINMENT PUBLICATION
* Janice Min, Owen Phil ips, Shanti Marlar, Jennifer Laski & Matthew Bel oni, The
Hol ywood Reporter
* Lavender Vroman, Daniel Wil iams, Lisa Wolf & Steve Calderon, Antelope Val ey Press
E. TV/VIDEO/FILM
E1 - NEWS
* Cheryl Diano, George Pennacchio & Cari Skil man, KABC-TV, "The Sudden Death of
Whitney Houston"
* David Perel & Radar Online, Radar Online, "J. Lo’s Reality TV Show Caught On Video
Faking Scenes”
E2A - FEATURE
* Christine Devine, Burke Ewing, Steve Adams & Dave Bush, KTTV Fox 11 News, “Bunk
Wurth/Paralyzed Painter”
* Cheryl Diano, George Pennacchio & Cari Skil man, KABC-TV, "The Style High Club:
‘Pan Am’ Fashions"
* Mae Ryan, 89.3 KPCC, “Transactivations”
* Grant Slater, 89.3 KPCC, “Rise of the Tubers”
* Chris Van Vliet, Ed Louloudis & David Spangler, WOIO-TV, "An Iron Wil : The Gregory
Iron Story”
E2B - FEATURE, CELEBRITY ORIENTED
* Jake Hamilton, Fox Houston, KRIV-TV, “Jake’s Takes”
* Jennifer Laski, Raphael Laski, Fabien Constant & Pablo Teyssier-Verger, The Hol ywood
Reporter, “Cannes Video Diaries”
* Kevin McCarthy, WTTG-TV, “Interview with Steven Spielberg for The Adventures of
TinTin”
* Jennifer Laski, Jennifer Sargent, Raphael Laski & Paolo Cascardo, The Hol ywood
Reporter, “Conan O’Brien: Behind the Scenes at the Cover Shoot May 2012”
* Radar Online Team, Radar Online, "Kel y Osbourne Video Interview: ‘I Am A Hypocrite
For Drinking’”  

E3 - CRITIC - SEE B4

E4 - DOCUMENTARY OR SPECIAL PROGRAM, SHORT
* Christine Devine, Darnel Cates, Shel y Insheiwat, Debbie Kim & Dave Hol oway,
KTTV/Fox 11 News, “Wednesday’s Child: Rising Stars”
* Juan Devis, Drew Tewksbury, Bruce Dickson & Justin Cram, KCET, “Artbound,
Date Farmers: Desert Detritus Becomes Chicano Pop Art”
* Rick Reiff, PBS, “PBS SoCal: Placido Domingo”  
E5 - DOCUMENTARY OR SPECIAL PROGRAM, FEATURE
* Juan Devis, Drew Tewksbury, Bruce Dickson & Justin Cram, KCET,
“Artbound: Episode 1”
* Donna Kanter, Nausheen Dadabhoy, Kanter Company, “Lunch”
* Jennifer Laski, Jennifer Sargent, Stacey Wilson, Matthew Bel oni & Victor Klaus, The
Hol ywood Reporter, “Emmy Drama Actors Roundtable June 2012”
F. RADIO
F1 - NEWS
* Larry Mantle & Karen Fritsche, 89.3 KPCC, “The History And Future of Hol ywood Film
Music”
* Larry Mantle, Linda Othenin-Girard, Karen Fritsche, Katie Sprenger & Jasmin Tuffaha,
89.3 KPCC, “HBO Cancels ‘Luck’ After Third Horse Dies”
* Sanden Totten, 89.3 KPCC, “Farewel Harry Potter”
F2 - PERSONALITY PROFILE
* Ashley Bailey, 89.3 KPCC, “Sumo Champ in Hol ywood”
* Richard Franzi, OCTalkRadio.Net, “Critical Mass Radio Show”
* Katie McMurran, Brian Lauritzen & Gail Eichenthal, KUSC Radio, “Gary Oldman with
Gail Eichenthal”
* Katie McMurran, Brian Lauritzen & Gail Eichenthal, KUSC Radio, “Gabriel Kahane: A
Brooklyn Composer on Loving L.A.”
* Brian Watt, 89.3 KPCC, “Don Cornelius”
F3 - FEATURE
* Kevin Ferguson, 89.3 KPCC, “Adult Film Industry Condom Law”  
* Katie McMurran, Brian Lauritzen & Gail Eichenthal, KUSC Radio, “Gay Men’s Chorus of
Los Angeles Perform Tolerance”  
* Katie McMurran, Brian Lauritzen & Gail Eichenthal, KUSC Radio, “Victor Hugo Zayas: Mi
Obra”
* Steve Rowland, Steve Robinson, Tony Macaluso & Jon Tolansky, public radio
freelancer, “Shakespeare Moments: Globe to Globe”
* Sanden Totten, 89.3 KPCC, “The Physics Behind The Hit Game Angry Birds”  
F4 - CRITIC - SEE B4

G. ONLINE
G1 - NEWS
* Lesley Goldberg, The Hol ywood Reporter, “’Glee’: Lea Michele, Chris Colfer, Cory
Monteith Not Returning for Season 4”
* Dylan Howard, Celebuzz, “Caught On Tape: Chevy Chase Rips His Own TV Program,
Community”
* Michael Rothman, Hol ywood.com, “Joe Manganiel o Hints at a ‘Magic Mike’ Prequel”
* Sharon Waxman, The Wrap, “Mel Gibson Vs. Joe Eszterhas on Maccabee Movie”
* Michael White & Ronald Grover, Bloomberg News, “Lions Gate Acquires Summit
Entertainment for $412.5 Mil ion”
G2 - PERSONALITY PROFILE
* Deborah Behrens, LA STAGE Times, “Anne Bogart Keeps Walking With Trojan Women”
* Vickie Chang, TheAtlantic.com, “The Punk Rocker Who Would Be Judge”
* Andy Fixmer, Bloomberg News, “Mophonics Turns Jingles Into Singles With Mark Foster
Grammy Nod”
* Matt Patches, Hol ywood.com, “The Hulk Problem: Lou Ferrigno on Marvel’s Struggles to
Bring the Hero to Screen”
* Allegra Tepper, Neon Tommy, “Shepard Fairey: Rebel With A Cause”

G3A - FEATURE/SERIES
* Mike Fleeman, People.com, “Andy Whitfield”
* Christopher Hawthorne & Los Angeles Times Video and Entertainment Online Web
Team, Los Angeles Times, “On the Boulevards: Atlantic on the Move”
* Michael Hogan, Huffington Post Media Group, “Indie Producers Wrestle With Big
Dreams and Smal Budgets”  
* Mitch Myers, The Hol ywood Reporter, “Murdoch Vs. Allen Ginsberg’s ‘Moloch’: The Mash-Up” * Allegra Tepper, Neon Tommy, “Passion in Poverty: Festival For All Skid Row Artists”   G3B - COMMENTARY ANALYSIS/TREND
* Eriq Gardner, The Hol ywood Reporter, “Hol ywood Confronts SOPA Uprising”
* Taylor Hamby, OC Weekly, “Top Protest Songs Hijacked by Patriots”
* Brent Lang, The Wrap, “Why Television, Not Film, Is Driving Profits at Major Media
Companies”
* Lucas Shaw, The Wrap, “How the Second Screen is Revolutionizing Television”
* Don Shirley, LA STAGE Times, “LA STAGE Watch”  
* Allegra Tepper, USATODAY Col ege, “The Search for Authenticity and Entertainment in
‘Girls’”  
G4 - CRITIC
* Mark Dujsik, Mark Reviews Movies, “Mark Reviews Movies”
* Tim Goodman, The Hol ywood Reporter, “Tim Goodman TV Criticism”
* Maureen Ryan, Huffington Post Media Group, “Online Critic”
* Allegra Tepper, Neon Tommy, “Assorted Reviews”
* Mel White, Truthdig, “Jesus Was Lynched”  
G5 - ENTERTAINMENT WEBSITE
* Michael Hogan, Kia Makarechi, Christopher Rosen & Mike Ryan, Huffington Post Media
Group, “Huffington Post Entertainment”
* Staff of People.com, “People.com”
* Juan Devis, Drew Tewksbury, Bruce Dickson & Justin Cram, KCET, “Artbound”
* RadarOnline, “RadarOnline.com”
* Sharon Waxman, Lisa Fung & Lew Harris, The Wrap, “The Wrap News”
* Staff of The Hol ywood Reporter, “Hol ywoodReporter.com”  
G6 - ENTERTAINMENT BLOG BY AN INDIVIDUAL
* Lil edeshan Bose, OC Weekly, “Ryan Adams at the Balboa Theater in San Diego Last
Night”
* Scott Feinberg, The Hol ywood Reporter, “The Race”
* James Franco, Huffington Post Media Group, “The Blog”
* Manny Pacheco, freelance, “Forgotten Hol ywood”
* Sharon Waxman, The Wrap, “Waxword”  
H. SOCIAL MEDIA
H1 - TWEET
* Dylan Howard, Celebuzz, “Whitney Houston’s Death – Happening Right Now”
H2 - FACEBOOK PRESENCE, ORGANIZATION
* Todd Gold & Robin Dagostino, Xfinity TV, “Facebook/Xfinity TV”
H3 - FACEBOOK PRESENCE, INDIVIDUAL
N/A
I. PHOTOGRAPHY
I1 - PORTRAIT
* Jay L Clendenin, Los Angeles Times, “JJ Abrams”
* Jennifer Laski, Shanti Marlar, Jenny Sargent, Carrie Smith & Wesley Mann, The
Hol ywood Reporter, “Michael J. Fox”
* Shanti Marlar, Jennifer Laski, Jenny Sargent, Carrie Smith & Wesley Mann, The
Hol ywood Reporter, “Spike Lee”
* Kirk McKoy, Los Angeles Times, “Nicki Minaj”
* Genaro Molina, Los Angeles Times, “Fiona Apple”
I2 - NON PORTRAIT
* Robert Gauthier, Los Angeles Times, “Jean and Uggie”
* Robert Gauthier, Los Angeles Times, “Adel Wins”
* Jennifer Laski, Shanti Marlar, Jenny Sargent, Carrie Smith & Joe Pugliese, The
Hol ywood Reporter, “Conan O’Brien”
* Jennifer Laski, Shanti Marlar, Jenny Sargent, Carrie Smith & Ruven Afanador, The
Hol ywood Reporter, “Matt Lauer”
* Genaro Molina, Los Angeles Times, “Skril ex in Action”

Source: http://lapressclub.org/wp-content/uploads/2012/10/Finalists_NEJ_2012.pdf