Schaltvorgänge der Transkription Friedrich-Alexander-Universität Erlangen-Nürnberg International Symposium Molecular Control of Gene Expression
Invited speakers: Walter Birchmeier Berlin, Germany Richard G. Brennan Portland, USA Martin Eilers Marburg, Germany Roger D. Everett Glasgow, UK Hiroshi Handa Yokohama, Japan Wolfgang Hillen Erlangen, Germany Heidelberg, Germany Axel Imhof Munich, Germany Christoph W. Müller Grenoble, France Christos A. Ouzounis Cambridge, UK Francois Parcy Gif-sur-Yvette, France Sebastien Rigali Liege, Belgium Walter Schaffner Zürich, Switzerland John Sinclair Cambridge, UK Robert Slany Erlangen, Germany Heinrich Sticht Erlangen, Germany Gilles P. van Wezel Leiden, The Netherlands Michael Wegner Erlangen, Germany Jerry L. Workman Kansas City, USA Organizers: Thomas Stamminger, Jürgen Behrens, Stefan Hoth, Robert Slany, Heinrich Sticht
Center Research Grant SFB 473, Graduiertenkolleg GRK 805
Additional information at www.biologie.uni-erlangen.de/sfb473.html Program of the Symposium Friday, Oct. 15, 2004: Venue of the scientific meeting: Lecture Hall of the Institute of Biochemistry, Fahrstr. 17 8.50 Welcome Wolfgang Hillen, Erlangen Session I: Molecular structure of transcription factors Richard G. Brennan, Portland, USA Structural mechanisms of carbon catabolite repression in gram positive bacteria
Christoph Müller, Grenoble, France Structural biology of general and sequence-specific eucaryotic transcription factors
Wolfgang Hillen, Erlangen, Germany Tetracycline dependent gene regulation – mechanisms and application
Coffee break Session II: Control of transcription by chromatin remodelling Axel Imhof, Munich, Germany Regulation of histone methyltransferase activity modulates permanent repression states
John Sinclair, Cambridge, UK Chromatin remodelling during human cytomegalovirus latency, reactivation and productive infection
Session III: Molecular machines in gene expression Hiroshi Handa, Yokohama, Japan Molecular insights into mechanism of DSIF, NELF and Spt6 in controlling transcription elongation by RNA polymerase II
Connections between transcription and mRNA export
Roger Everett, Glasgow, UK PML nuclear body components actively relocate to sites associated with HSV1 transcription/replication complexes early during productive virus infection
Coffee break Session IV: Transcriptional switches in development and disease I Walter Birchmeier, Berlin, Germany Wnt/beta-catenin signalling in embryogenesis and tumor progression
Michael Wegner, Erlangen, Germany Sox proteins and transcriptional control of development
Francois Parcy, Gif-sur-Yvette, France Gene regulatory network controlling Arabidopsis seed maturation
Gilles van Wezel, Leiden, The Netherlands
Control of cell division and morphogenesis of Streptomyces
Saturday, Oct. 16, 2004 Session V: Transcriptional switches in development and disease II Walter Schaffner, Zürich, Switzerland Transcriptional response to heavy metal stress
Martin Eilers, Marburg, Germany Transcriptional regulation and transformation by myc
Robert Slany, Erlangen, Germany Deregulation of homeobox genes in leukemia
Coffee break Session VI: Deciphering transcriptional networks Sebastien Rigali, Liege, Belgium Extending the classification of bacterial transcription factors beyond the helix-turn-helix motif as an alternative approach to discover new cis/trans relationships
H. Sticht, Erlangen, Germany Development of structure-based computational approaches to identify new components of regulatory protein networks
Concluding remarks by Wolfgang Hillen General Information Meeting Address Institut für Biochemie, Emil-Fischer-Zentrum Fahrstr. 17, 91054 Erlangen www.biochem.uni-erlangen.de/kontakt/lageplan.htm Registration No registration is required Contact Frau Heidemarie Prell Sekretariat des SFB473 Lehrstuhl für Mikrobiologie Institut für Mikrobiologie, Biochemie und Genetik Staudtstr. 5 91058 Erlangen Tel.: +49 9131 852 8588 Fax: +49 9131 852 8082 hprell@biologie.uni-erlangen.de Hotels A list of hotels in Erlangen is available at www.erlangen.de (City-Tourist- Info)
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Case 10 Controlling Trachoma in Morocco Geographic area: morocco Health condition: in 992, a national survey found that just over 5 percent of morocco’s population had the blinding disease trachoma. nearly all the cases were concentrated in five poor, rural provinces in the southeast of the country where 25,000 people showed a serious decline in vision due to trachoma, 625,000 neede