Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

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200 COUNT FULL COVER ACTIVE SQUARE UNDECORATED SO NATURAL EVERYDAY FRENCH ARTIFICIAL NAILS GLUE: ETHYL CYANOACRYLATE, POLYMETHYL METHACRYLATE, BHA, METHOXY‑
GLUE/COLLE: ETHYL CYANOACRYLATE. / INGREDIENTES: PEGEMENTO: CIANO‑
ISOPROPYL, ACETATE, PEG‑22, DIMETHACRYLATE, 2‑BROMO‑2‑NITROPROPANE‑1, 3‑DIOL, RED 7 (CI 15850). NAILS: METHYL METHACRYLATE ABS (ACRYLONI‑
200 COUNT CURVE OVERLAP UNDECORATED ARTIFICIAL NAILS
GLUE/COLLE: ETHYL CYANOACRYLATE. / INGREDIENTES: PEGEMENTO: CIANO‑
GLUE: ETHYL CYANOACRYLATE, POLYMETHYL METHACRYLATE, BHA, METHOXY‑
ISOPROPYL, ACETATE, PEG‑22, DIMETHACRYLATE, 2‑BROMO‑2‑NITROPROPANE‑1, SPARKLE COAT: ETHYL ACETATE, BUTYL ACETATE, ISOPROPYL ALCOHOL, NI‑
NAILS: METHYL METHACRYLATE ABS (ACRYLONITRILE‑BUTADIENE‑STYRENE).
TROCELLULOSE, ADIPIC ACID / NEOPENTYL GLYCOL / TRIMELLITIC ANHYDRIDE COPOLYMER, TRIMETHYL PENTANYL DIISOBUTYRATE, TRIPHENYL PHOSPHATE, STEARALKONIUM HECTORITE, DIACETONE ALCOHOL, CITRIC ACID, BENZOPHE‑ GLUE: ETHYL CYANOACRYLATE, POLYMETHYL METHACRYLATE, BHA, METHOXY‑
NONE‑1. MAY CONTAIN (±): MICA (CI 77019). ISOPROPYL ACETATE, POLYETHYLENE GLYCOL DIMETHACRYLATE, RED 7 (CI 15850), STRIPER: ETHYL ACETATE, BUTYL ACETATE, NITROCELLULOSE, ALCOHOL DENAT.,
2‑BROMO‑2‑NITROPROPANE‑1,3‑DIOL.
ADIPIC ACID / NEOPENTYL GLYCOL / TRIMELLITIC ANHYDRIDE COPOLYMER, ISOPROPYL ALCOHOL, TRIPHENYL PHOSPHATE, TRIMETHYL PENTANYL DI SOBU‑ SO NATURAL EVERYDAY FRENCH ULTRA FLEX ARTIFICIAL NAILS TYRATE, STYRENE ACRYLATES COPOLYMER, SILICA, POLYETHYLENE TEREPHTHAL‑ GLUE: ETHYL CYANOACRYLATE, POLYMETHYL METHACRYLATE, BHA, METHOXY‑
ATE, ISOBUTYLPHENOXY EPOXY RESIN. MAY CONTAIN (±): ALUMINUM POWDER ISOPROPYL, ACETATE, PEG‑22, DIMETHACRYLATE, 2‑BROMO‑2‑NITROPROPANE‑1, 3‑DIOL, RED 7 (CI 15850).
NAILS: METHYL METHACRYLATE ABS (ACRYLONITRILE‑BUTADIENE‑STYRENE).
ACRYLIC FILL KIT
POWDER: POLYMETHYL METHACRYLATE, POLYETHYLMETHAC RYLATE, BENZOYL
ACRYLIC LIQUID: ETHYL METHACRYLATE, GLYCOL DIMETHACRYLATE, DIMETH‑
PROFESSIONAL FRENCH MANICURE KIT
WHITE POLISH/COLORED POLISH (BABY’S BREATH/COSMIC SAND/PETAL
PUSHER): ETHYL ACETATE, BUTYL ACETATE, NITROCELLULOSE, PHTHALIC
ANHYDRIDE/TRIMELLITIC ANHYDRIDE/GLYCOLS COPOLYMER, ISOPROPYL ALCOHOL, SUCROSE ACETATE ISOBUTYRATE, ACRYLATES COPOLYMER, N‑BUTYL ALCOHOL, ACETYL TRIBUTYL CITRATE, CAMPHOR, STEARALKONIUM HECTORITE, ETHYL CYANOACRYLATE, RED 6 (CI 15850).
CITRIC ACID, BENZOPHENONE‑1. MAY CONTAIN (±): BISMUTH OXYCHLORIDE (CI 77163), MICA (CI 77019), RED 6 (CI 15850), TITANIUM DIOXIDE (CI 77891), YELLOW 5 COLORED POLISH (SHEER PINK/SASSY PINK): ETHYL ACETATE, BUTYL ACETATE,
ISOPROPYL ALCOHOL, NITROCELLULOSE, ADIPIC ACID / NEOPENTYL GLYCOL / TRIMELLITIC ANHYDRIDE COPOLYMER, TRIMETHYL PENTANYL DIISOBUTYRATE, C12‑15 ALKANE / CYCLOALKANE / AROMATIC HYDROCARBONS, HYDROGENATED TRIPHENYL PHOSPHATE, STEARALKONIUM HECTORITE, DIACETONE ALCOHOL, C6‑20 POLYOLEFIN, POLYBUTENE, HYDRATED SILICA, 1,3‑BENZENEDICARBOX‑ BENZOPHENONE‑1, CITRIC ACID, DIMETHICONE. MAY CONTAIN (±): RED 6 LAKE YLIC ACID, POLYMER WITH 1,4‑BENZENEDICARBOXYLIC ACID, 2,2‑DIMETHYL‑1,3‑ (CI 15850), RED 7 LAKE (CI 15850), IRON OXIDES (CI 77491), TITANIUM DIOXIDE PROPANEDIOL, 1,2‑ETHANEDIOL AND HEXANEDIOIC ACID/ACIDE BENZÈNE‑1,3‑ DICARBOXYLIQUE POLYMÉRISÉ AVEC L’ACIDE BENZÈNE‑1,4‑DICARBOXYLIQUE, LE 2,2‑DIMÉTHYLPROPANE‑1,3‑DIOL, L’ÉTHANE‑1.2‑DIOL ET L’ACIDE HEXANEDIOÏQUE.
TOP COAT: ETHYL ACETATE, BUTYL ACETATE, NITROCELLULOSE, ACETYL TRIBUTYL
CITRATE, ADIPIC ACID/NEOPENTYL GLYCOL/TRIMELLITIC ANHYDRIDE COPOLYMER, ISOPROPYL ALCOHOL, TRIMETHYLPENTANEDIYL DIB ENZOATE, POLYVINYL POLYETHYLENE, ACRYLAMIDES COPOLYMER, MEK, WATER (AQUA).
BUTYRAL, BENZOPHENONE‑1, VIOLET 2 (CI 60725).
TIP GUIDES: POLYCYCLOPENTADIENE, STYRENE/ISOPRENE COPOLYMER, MINERAL
OIL(PARAFFINUM LIQUIDUM), STYRENE/METHYLSTYRENE COPOLYMER.
C12‑15 ALKANE / CYCLOALKANE / AROMATIC HYDROCARBONS, HYDROGENATED C6‑20 POLYOLEFIN, POLYBUTENE, HYDRATED SILICA, 1,3‑BENZENEDICARBOX‑ YLIC ACID, POLYMER WITH 1,4‑BENZENEDICARBOXYLIC ACID, 2,2‑DIMETHYL‑1,3‑ ACETONE, ETHYL ACETATE, DIMETHYLTOLYAMINE./INGRÉDIENTS: ACÉTONE,
PROPANEDIOL, 1,2‑ETHANEDIOL AND HEXANEDIOIC ACID/ACIDE BENZÈNE‑1,3‑ ACÉTATE D’ÉTHYLE, DIMÉTHYLTOLYAMINE.
DICARBOXYLIQUE POLYMÉRISÉ AVEC L’ACIDE BENZÈNE‑1,4‑DICARBOXYLIQUE, LE 2,2‑DIMÉTHYLPROPANE‑1,3‑DIOL, L’ÉTHANE‑1.2‑DIOL ET L’ACIDE HEXANEDIOÏQUE.
PROFESSIONAL FRENCH TIP PEN KIT
PEN (WHITE): WATER (AQUA), TITNIUM DIOXIDE (CI 77891), AMMONIUM STYRENE/
ACRYLATES COPOLYMER, PROPYLENE GLYCOL, PEG‑8 DIMETHICONE, BENZISO‑ ACETONE, METHYL PYRROLIDONE, BUTYL STEARATE, D‑LIMONENE, DENATONIUM THIAZOLINONE. COLORED POLISH ETHYL ACETATE, BUTYL ACETATE, ISOPROPYL ALCOHOL, NITROCELLULOSE, ADIPIC ACID/NEOPENTYL GLYCOL/TRIMELLITIC ANHYDRIDE COPOLYMER, TRIMETHYL PENTANYL DIISOBUTYRATE, TRIPHENYL PHOSPHATE, STEARALKONIUM HECTORITE, DIACETONE ALCOHOL, CITRIC ACID, DIMETHICONE, BENZOPHENONE‑1. MAY CONTAIN (±): RED 6 LAKE (CI 15850), RED 7 LAKE (CI 15850), TITANIUM DIOXIDE (CI 77891). TOP COAT: ETHYL ACETATE, ALCOHOL DENAT, BUTYL ACETATE, NITROCELLULOSE,
ETHYL CYANOACRYLATE, POLYMETHYL METHACRYLATE, RED 6 (CI 15850).
ADIPIC ACID/NEOPENTYL GLYCOL/TRIMELLITIC ANHYDRIDE COPOLYMER, ALCOHOL DENAT , N‑BUTYL ALCOHOL, TRIMETHYL PENTANYL DIISOBUTYRATE, TRIPHENYL PHOSPHATE, CAMPHOR, BENZOPHENONE‑1, RED 17 (CI 26100), VIOLET 2 (CI 60725).
ETHYL ACETATE, ALCOHOL DENAT., BUTYL ACETATE, NITROCELLULOSE, ADIPIC TIP GUIDES: POLYCYCLOPENTADIENE, STYRENE/ISOPRENE COPOLYMER, MINERAL
ACID/NEOPENTYL GLYCOL/TRIMELLITIC ANHYDRIDE COPOLYMER, ISOPROPYL OIL (PARAFFINUM LIQUIDUM), STYRENE/METHYLSTYRENE COPOLYMER.
ALCOHOL, N‑BUTYL ALCOHOL, TRIPHENYL PHOSPHATE, TRIMETHYL PENTANYL DIISOBUTYRATE, CAMPHOR, BENZOPHENONE‑1, VIOLET 2 (CI 60725).
ACRYLIC SCULPTURE KIT
POWDER: POLYMETHYL METHACRYLATE, POLYETHYLMETHACRYLATE, BENZOYL
ETHYL 2‑CYANOACRYLATE, POLYMETHYL METHACRYLATE.
ACRYLIC LIQUID: ETHYL METHACRYLATE, GLYCOL HEMA‑METHACRYLATE, DI‑
METHYLTOLYAMINE, BENZOPHENONE, BLUE 1 (CI 42090).
Heritage Brands (Australia) Pty. Ltd.
30 Bando Rd, Springvale, VIC 3171, Australia. Customer Service: 1300 650 981.

Source: http://nailene.com.au/documents/Nailene-Ingredients-List.pdf