Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Website alpha drug list 06-08-04.xls

PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.
PICA Drug List - Alphabetial Listing
Key:
MAND. MAIL
= the indicated medication must be ordered through CFI Mail Order.
STP = the indicated medication is subject to the Step Therapy Program:use 1st line agents (or
generics) first
FER = the indicated medication is indicated for the treatment of infertility. SPBM = the indicated medication is only available through CuraScript after one fill the retail pharmacy.
A 90-day (or 3 cycle) lifetime limit applies for all Fertility medications.
All prescriptions dispensed by CuraScript will be for a 30-day supply. PA = the indicated medication requires prior approval
* = this symbol next to a drug signifies that it is subject to non-
formulary status when a generic equivalent is available
Formulary Status:
F
= Medication is a formulary drug and will pay at the 1st or 2nd tier copay.
N = Medication is a NOT a formulary drug and will pay at the 3rd tier copay.
Formulary Mandatory
Medication Name
PICA Category
Please be advised that this list is not all-inclusive and does not guarantee coverage.

Source: http://www.osaunion.org/member/picadruglist.pdf

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