Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.
PTCI holding for all listed compounds its own developed Process Know How.
The list is intended to give chemists a representative reference of process development and
We have numerous API’s and Key Intermediates exclusive developed for customers
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PEN TSAO CHEMICAL INDUSTRY LTD. Active Pharmaceutical Ingredients - API’s Product Name
Products in Bold Italic are currently produced & marketed.
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to intellectual property protection existing in their country.
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PEN TSAO CHEMICAL INDUSTRY LTD. Cont. - Active Pharmaceutical Ingredients - API’s Product Name
Products in Bold Italic are currently produced & marketed.
It is the customer’s obligation to observe and follow existing legislation and regulations in regard
to intellectual property protection existing in their country.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
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PEN TSAO CHEMICAL INDUSTRY LTD. CAS No. Listing API’s CAS-No
Products in Bold Italic are currently produced & marketed.
It is the customer’s obligation to observe and follow existing legislation and regulations in regard
to intellectual property protection existing in their country.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
Tel: 852 2511 3131, Fax: 852 2511 3030, email: info@pen-tsao.com
Products in Bold Italic are currently produced & marketed.
It is the customer’s obligation to observe and follow existing legislation and regulations in regard
to intellectual property protection existing in their country.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
Tel: 852 2511 3131, Fax: 852 2511 3030, email: info@pen-tsao.com
PEN TSAO CHEMICAL INDUSTRY LTD. Therapeutic Application Listing – API’s
Products in Bold Italic are currently produced & marketed.
It is the customer’s obligation to observe and follow existing legislation and regulations in regard
to intellectual property protection existing in their country.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
Tel: 852 2511 3131, Fax: 852 2511 3030, email: info@pen-tsao.com
Cont. - Therapeutic Application Listing – API’s
Products in Bold Italic are currently produced & marketed.
It is the customer’s obligation to observe and follow existing legislation and regulations in regard
to intellectual property protection existing in their country.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
Tel: 852 2511 3131, Fax: 852 2511 3030, email: info@pen-tsao.com
PEN TSAO CHEMICAL INDUSTRY LTD. Intermediates Product Name
2-(4-Bromomethylphenyl)-propionic Acid 111128-12-2 98 % Loxoprofen
Products in Bold Italic are currently produced & marketed.
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PEN TSAO CHEMICAL INDUSTRY LTD. Cont. - Intermediates Product Name
2-(5-Fluoro-2-methylinden)-3-yl Acetic Acid
1-(3-(Hydroxymethyl)-pyridyl-2)-2-phenyl-
Products in Bold Italic are currently produced & marketed.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
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4-Methyl-N-phenyl-6-(2-chloropropenyl-1) 110235-47-7
Products in Bold Italic are currently produced & marketed.
It is the customer’s obligation to observe and follow existing legislation and regulations
in regard to intellectual property protection existing in their country.
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
Tel: 852 2511 3131, Fax: 852 2511 3030, email: info@pen-tsao.com
Contact PTCI HK for inquiries and quotes.
Notes: __________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________ ________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________
27B, CKK Commercial Centre, 289 Hennessy Road, Wanchai, Hong Kong
Tel: 852 2511 3131, Fax: 852 2511 3030, email: info@pen-tsao.com
Source: http://www.pen-tsao.com/fileadmin/fohNg1oh/pdf-Doc/PTCI-Product-List-2013.pdf
B I O T E C H ’ S M O S T R E S P E C T E D N E W S S O U R C E F O R O V E R 1 5 Y E A R S T H E D A I L Y B I O T E C H N O L O G Y N E W S P A P E R KAI’s PKC Program Nabs Tioga’s Series A Round: $24M $340M Deal With Sankyo For Phase IIb Trial Of IBS Drug KAI Pharmaceuticals Inc. signed a potential $340 mil-Six months after licensing a promising early stagelion dea
Interview with Marjorie Herdes and William Stockton: Practitioners of the Year. By Christine Herdes MARK YOUR CALENDARS Upcoming MNODN Monthly Meetings March 4th 3:30 – 5:30 pm, Finding Your Compass: Aligning Organizational Culture with Development Network recognizes an individual who has made significant It’s my understanding that the award was April 1st 3:30 – 5:30 pm,