Medicamentsen-ligne vous propose les traitements dont vous avez besoin afin de prendre soin de votre santé sexuelle. Avec plus de 5 ans d'expérience et plus de 80.000 clients francophones, nous étions la première clinique fournissant du acheter levitra original en France à vente en ligne et le premier vendeur en ligne de Cialis dans le monde. Pourquoi prendre des risques si vous pouvez être sûr avec Medicamentsen-ligne - Le service auquel vous pouvez faire confiance.

Plasmalife.it

PlasmaLife
Frozen fresh equine plasma for horses
Active ingredients Quantity
IgG ≥ 24 < 40 g/L
Total proteins ≥ 50 < 90 g/L
Excipients
ACD-A citrates (expressed as citrate ion) < 4.73 g/L
INDICATIONS
Equine plasma is used to increase IgG in hypogammaglobulinemic foals (IgG < 8 g/L) for failed transfer of colostral immunity
during the period between birth and 6 days of age.

CONTRAINDICATIONS
Do not use in case of intolerance to the immunoglobulins or excipients contained.
Do not use in species other than the intended use species.
Do not use in pregnant or lactating mares.
Do not use in horses of ages other than the authorized ones.
Do not use a route of administration other than the intravenous route.

ADVERSE REACTIONS
The risk of adverse drug reactions is extremely low.
Immunological reactions of an anaphylactic type may arise following administration of equine plasma due to the presence of
red blood cells or protein aggregates. The clinical signs of the anaphylactic reaction are characterized by tachycardia,
tachypnea, hives, hyperthermia, cardiac arrhythmia, muscle tremors, colic, and collapse.
The cardiac and respiratory parameters of the receiver must above all be carefully monitored when starting the administration
of the plasma. A slow infusion at the start of the administration allows the receiving foal to show the first signs of reaction at
an early stage so as to allow prompt intervention to counteract the reaction itself. If this happens, reduce the velocity of
administration for 5-10 minutes or stop it completely. It is advisable to have available epinephrine (0.01 mg/kg),
corticosteroids (prednisolone from 0.25 to 1 mg/kg slow IV), flunixin meglumine (1.1 mg/kg IV) and intravenous saline
solutions, which must be used by the veterinarian administering the plasma in the case that anaphylactic shock occurs.
However, since both the IgG and other proteins present in the plasma do not degrade and do not coagulate if the product is
stored according to the described procedure, the risk of an anaphylactic reaction is notably reduced.
Furthermore, the use of special infusion sets for the transfusion with filters to retain any corpuscular particles present in the
plasma almost completely eliminates this risk.
An excess of citrates can cause muscle fasciculations, weakness and cardiac abnormalities. However, the equine plasma
contains a negligible amount of these in relation to the plasmatic mass of the receiving subject and studies conducted on the
product’s safety in foals from 24 hours to 3 months old have not shown problems in this regard.
If serious adverse reactions or other reactions not mentioned in this information leaflet occur, please inform the veterinarian.
INTENDED USE SPECIES
Horses.
DOSAGE, ROUTE AND METHOD OF ADMINISTRATION
The recommended dose of plasma is 20 ml per kilogram of live weight. One liter can be administered to a foal (45 – 50 kg) in
a period of at least 20 minutes. It is recommended to begin the administration slowly (for the first 50-100 ml) and to carefully
monitor the receiver. The complications, though rare, are well-characterized by symptoms such as tachypnea, tachycardia,
tremors and colic. If this happens, reduce the velocity of administration further for 5-10 minutes or stop it completely.
The foal must then be subjected to a test for the evaluation of serum IgG. If the IgG level has remained below 8 g/L after the
first administration, it is advisable to administer a second bag of plasma. The latter must not be administered before 6 hours
have passed after the first infusion.
The administration occurs through infusion into the jugular vein of the foal into which a 14G x 2” catheter has previously been
inserted, in an aseptic manner, following shaving and local anesthesia at the injection site. The entire bag of plasma is then
administered to the foal within at least 20 minutes using a special infusion set with a filter to trap any protein aggregates.
ADVICE ON CORRECT ADMINISTRATION
The transient increase of the antibody titer that is found in the bloodstream after the administration of PlasmaLife can give rise
to false positives in the serological tests.
The effectiveness of the product depends on the immune status and on the possible presence of disease in the receiver.
The administration of the medicinal product must only be performed by the veterinarian.
WITHDRAWAL PERIOD
Zero days.
SPECIAL PRECAUTIONS FOR STORAGE
Keep out of reach of children.
Store in the original packaging, unopened, at a temperature of -20°C ± 5°C.
Do not use after the expiry date stated on the label.
The product must be used within 6 hours of thawing.
After opening the product must immediately be completely used and not stored.
SPECIAL WARNINGS
The transient increase of the antibody titer that is found in the bloodstream after the administration of PlasmaLife can give rise
to false positives in the serological tests.
The effectiveness of the product depends on the immune status and on the possible presence of disease in the receiver.
The administration of the medicinal product must only be performed by the veterinarian.
Special precautions for use in animals
It is recommended to begin the administration slowly (for the first 50-100 ml) and carefully monitor the receiver. The
complications, though rare, are well-characterized by symptoms such as tachypnea, tachycardia, tremors and colic. If this
happens, reduce the velocity of administration further for 5-10 minutes or stop it completely. If the signs stop within 5 minutes
you can continue the transfusion; if instead they occur again, you must definitively stop it. Be careful not to cause an overload
of the blood volume (infusion rate < 50 ml/min for a 50-kg foal).
Use the product only if it has been stored correctly, frozen at temperatures of -20 ± 5° C within the expiration date printed on
the package.
Thaw the product in a water bath at a temperature not greater than 37°C to limit flocculation and the formation of aggregates of
plasma proteins.
Administer the drug intravenously within 6 hours of thawing using a special infusion set with a filter to trap any protein
aggregates.
Special precautions that must be taken by the person that administers the product to the animals
In case of accidental spillage onto the skin, the drug is not harmful and can be removed with soap and water.
In case of accidental self-administration, self-injection or ingestion, contact a doctor immediately, showing him the
information leaflet or the label.
Use during pregnancy and lactation
The drug is not intended for use in adult horses.
The safety of the veterinary medicinal product on fertility has not been established.
Interaction with other veterinary medicinal products and other forms of interaction
Equine plasma has no interactions with numerous categories of drugs such as antimicrobials (e.g. penicillin, gentamicin,
oxytetracycline), non-steroidal anti-inflammatory drugs (e.g. flunixin meglumine), and corticosteroids (e.g. dexamethasone).
There is currently no evidence in the literature of interactions with other drugs administered concurrently to the foal.
However, since further studies have not yet been carried out in relation to interactions of the plasma with other drugs, we
recommend extreme caution in the concomitant administration of any drug with the plasma. In any case, since the risk of
contamination or alteration of the plasma proteins exists, it is contraindicated to combine other veterinary drugs with the
equine plasma.
Overdose (symptoms, emergency procedures, antidotes) if necessary
The consecutive administration of 2 or more liters of plasma or too fast of a transfusion of the plasma itself can cause an
overload of the blood volume with consequences on the foal’s cardiopulmonary system characterized by alterations in the heart
rate and breathing rate: in case these symptoms occur, immediately interrupt the administration, allowing the foal to
compensate for the increase in blood volume. Following the remission of the symptoms, the administration may be restarted
with a slower rate of infusion.
The administration of up to 4 liters of plasma in an appropriate period of time without side effects is however reported.
An excess of citrates (ACD) can cause muscle fasciculations, weakness and cardiac abnormalities. If these symptoms occur,
immediately interrupt the administration. However, the equine plasma contains a negligible amount of these in relation to the
plasmatic mass of the receiving subject and studies conducts on the safety of the product in foals from 24 hours to 3 months
old have not shown problems in this regard.
SPECIAL PRECAUTIONS TO TAKE FOR THE DISPOSAL OF THE UNUSED PRODUCT OR ANY WASTE
All veterinary medicinal products that have not been used, are visibly damaged, or that have packaging that is not intact and
the empty bags following transfusion must be disposed of in accordance with the local legislation and placed into appropriate
collection and disposal systems for unused or expired medicinal products.
NAME AND ADDRESS OF THE HOLDER OF THE AUTHORIZATION FOR MARKETING
Soc. IL CEPPO S.a.s. Via di Monteresi, 3 - 53035 Monteriggioni (SI) Italy

DATE OF THE LAST REVISION OF THE INFORMATION LEAFLET
January 2013

Source: http://www.plasmalife.it/pdf/leaflet.pdf

Microsoft word - convocatoria-2014-fy02.doc

ALQUILER PARA EVENTOS DE GOBIERNO I. Consideraciones Generales El Teatro Nacional de Costa Rica (TNCR) cobra vida en la interacción del binomio compuesto por la conservación del patrimonio material y la promoción de las artes escénicas del más alto nivel artístico. Con la intención de mejorar la estrategia de diseño de programación de sus distintos espacios, el Consejo Directivo

Thing

Defense Logistics Agency’s Year 2000 Program Managing Organization-Wide Conversion and Compliance Sarah J. Reed Defense Logistics Agency System Design Center The Defense Logistics Agency considers the year 2000 (Y2K) problem mission-critical, and we have treated itas such in planning and executing the largest maintenance effort we have undertaken. The agency kicked offa formal Y2K pr

Copyright © 2010-2014 Pharmacy Pills Pdf