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Michael Keith Schrader, MD, FACP

Center for Executive Medicine
North Texas Medical Research
Curriculum Vitae
Professional Recognition and Certifications
Diplomate, American Board of Internal Medicine, 2001 Recertified 2011 Fellow, American College of Physicians, 2012 II. Education
M.D., University of Texas Southwestern Medical School, Dallas TX, 1998 B.S., Texas A&M University, College Station, 1994, University Honors in biochemistry research Work Experience

Private practice; office and hospital primary care and consultative Internal Medicine, 2001 - present Sub-Investigator, North Texas Medical Research; inpatient and outpatient clinical research, 2004 - present Internal Medicine Internship / Residency, University or North Carolina Hospitals, Chapel Hill, 1998 – 2001 IV. Volunteer Service, Community Activities and Recognition
Volunteer Faculty, Texas General Internal Medicine Student Preceptorship Program, 2006 – present Volunteer Faculty, Lake Erie College of Medicine, student externship program, 2008 – present Volunteer Consulting Physician, Metrocrest Family Medical Clinic, 2002 – 2005 V. Hospital Committee Memberships and Governance
Chair, Department of Internal Medicine, RHD Medical Center, 2004 – 2005 Member, Governing Board, RHD Medical Center, 2004 – 2005 Member, Internal Medicine Peer Review Committee, Presbyterian Hospital of Plano, 2011 – current Member, Patient Care and Quality Committee, Presbyterian Hospital of Plano, 2008 - 2010 Curriculum Vitae Michael Keith Schrader, MD Page 1 of 9 Professional Society Memberships
American College of Physicians, 2001 – present Texas Medical Association, 2001 – present Collin County Medical Society, 2001 – present VII. Professional Society Committee Memberships and Governance
Member, Board of Directors, Texas Chapter of the American College of Physicians (formerly Texas Academy of Internal Medicine), 2009 – 2012 Member, Health and Public Policy Committee, Texas Chapter of the American College of Physicians, 2009 - 2012 VIII. Other Memberships and Governance
Member, Texas Medical Foundation, 2009 - present Member, Board of Directors, TexasFirst HMO Physician Counsel, 2007 - 2009 Human Research Studies
sanofi-aventis ACT11308:Randomized, double-blind, placebo-controlled study of the effect of a single injection of SAR164877 (REGN475) on reduction of pain from vertebral fracture associated with osteoporosis. Forest Research Institute DUT-MD-308: A Phase III, Randomized, Double-Blind, Active-Controlled, Multicenter Safety Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Mellitus Treated with Dutogliptin Compared to Glimepiride. sanofi-aventis EFC10781: A randomized, placebo-controlled, 2-arm parallel-group, multicenter study with a 24-week double-blind treatment period assessing the efficacy and safety of lixisenatide in patients with Type 2 diabetes insufficiently controlled with insulin glargine and metformin. sanofi-aventis: A Retrospective Clinical Practice Evaluation of Lantus Cost-Effectiveness Compared to Levemir in Insulin-Naïve Type 2 Diabetes Patients. Wyeth Research 3151A1-4415-NA: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study to Evaluate Functional Outcome in Outpatients with Major Depressive Disorder Treated with Desvenlafaxine Succinate Sustained Release. Bristol-Myers Squibb CV185030: A Phase3, Active (Warfarin) Controlled, Randomized, Double-Blind, Parallel Arm Study to Evaluate Efficacy and Safety of Apixaban in Preventing Stroke and Systemic Embolism in Subjects with Nonvalvular Atrial Fibrillation GlaxoSmithKline ADC 111116: Assessment of the Prevalence of Chronic Airway Obstruction in subjects with a history of Cigarette Smoking in a Primary Care Setting. Kowa K604-2.01US: A Phase II multi-center, randomized, double-blind, placebo controlled, parallel evaluation of the efficacy and safety of K-604 by High Resolution Magnetic Resonance Imaging (MRI) in carotid atherosclerotic plaque. General Electric Medical Systems Information Technology: Using Electronic Medical Records (EHR) – Based Disease Management Tools to Improve Management of Depression in Primary Care. Curriculum Vitae Michael Keith Schrader, MD Page 2 of 9 Pfizer GI-REASONS: Gastrointestinal (GI) Randomized Event and Safety Open-label NSAID Study (GI-REASONS): A Randomized, Open-Label, Blinded-Endpoint, Parallel-Group Trial of GI Safety of Celecoxib Compared with Non-Selective Nonsteroidal Anti-inflammatory Drugs (NSAIDS) in Osteoarthritis Patients. Takeda 322-OPI-004: A Multicenter, Randomized, Double-Blind Study to Determine the Efficacy and Safety of the Addition of SYR-322 25 mg versus Dose Titration from 30 mg to 45 mg of ACTOS Pioglitazone HCI in Subjects with Type 2 Diabetes Mellitus Who Have Inadequate Control on a Combination of Metformin and 30 mg of Pioglitazone HCI Therapy. Myogen/Gilead DAR-312 and 312-E (Extension of DAR-312): A Double-Blind, Active-Controlled, Long-Term Safety Extension Study of Optimized Doses of Darusentan in Subjects with Resistant Hypertension Despite Receiving Combination Therapy with Three or More Antihypertensive Drugs, Including a Diuretic, as Compared to Guanfacine. Akros Pharma Inc. AT302-U-06-003 A Phase 2, Randomized, Double-blind, Placebo-controlled, Parallel Group Study Evaluating the Efficacy and Safety of JTT-302 Administered Daily for Four Weeks in Subjects with Low HDL-C Levels. Novo Nordisk NN1998-1683: Inhaled Mealtime Insulin with the AERx® iDMS plus Pioglitazone versus Pioglitazone alone in Type 2 Diabetes: A 26-Week, Open-Label, Multicentre, Randomised, Parallel Trial to Investigate Efficacy and Safety. sanofi-aventis HMR1964A/3515: All To Target Trial Lantus® (insulin glargine) with stepwise addition of APIDRA (insulin glulisine) or Lantus with one injection of Apidra ®vs. a twice-daily premixed insulin regimen (Novolog® Mix 70/30) in adult subjects with type 2 diabetes failing dual or triple therapy with oral agents: a 64-week, multi-center, randomized, parallel, open label clinical study. Johnson & Johnson-Rocket AFib: A Prospective, Randomized, Double-Blind, Double-Dummy, Parallel-Group, Multicenter, Event-Driven, Non-inferiority Study Comparing the Efficacy and Safety of Once-Daily Oral Rivaroxaban (BAY 59-7939) With Adjusted-Dose Oral Warfarin for the Prevention of Stroke and Non-Central Nervous System Systemic Embolism in Subjects With Non-Valvular Atrial Fibrillation. Novartis CLAF237A23119 GALIANT: A multi-center, randomized, open-label, active controlled, parallel arm study to compare the efficacy of 12 weeks of treatment with Vildagliptin 100mg, qd to thiazolidinedione as add-on therapy in patients with type 2 diabetes inadequately controlled with metformin monotherapy in a community-based practice setting. BioCryst Pharmaceuticals, Inc. Protocol No. BCX1812-311: THE IMPROVE 1 STUDY: A phase 3 multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of intramuscular peramivir in subjects with uncomplicated acute influenza. Alba CLIN 1001-006 A Phase IIb, Randomized, Placebo Controlled, Dose Ranging, Multicenter Study to Determine the Safety, Tolerance, and Efficacy of AT-1001 in Celiac Disease Subjects during a Gluten Challenge. Pfizer A3841045: A 6-Week, Prospective, Randomized, Double-Blind, Double-Dummy Phase IV Clinical Trial Designed to Evaluate the Efficacy of an Aggressive Multi-Risk Factor Management Strategy with Caduet (A3841045) versus a Guideline-Based Approach in Achieving Blood Pressure and Lipid Goals in Hypertensive Subjects with Additional Risk Factors. Pfizer A3191172 PRECISION: Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen or Naproxen. Boehringer Ingelheim Pharma GmbH & Co. 1160.26 RE-LY: Randomized Evaluation of Long term anticoagulant therapy (RE-LY) comparing the efficacy and safety of two blinded doses of dabigatran etexilate with open label warfarin for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation: prospective, multi-center, parallel-group, non-inferiority trial (Re-LY STUDY). Curriculum Vitae Michael Keith Schrader, MD Page 3 of 9 Mannkind Corporation: MKC-TI-126: A 2-Month Safety Follow -Up of Subjects from Mannkind Protocols MKC-TI-009, MKC-TI-102, MKC-TI-103, and MKC-TI-030. Mannkind Corporation: MKC-TI-030: Pulmonary Outcomes within a 2-year Period in Subjects with Diabetes Mellitus Treated with Technosphere®/Insulin or Usual Antidiabetic Treatment and in Subjects without Abnormalities in Glucose Control. Boehringer Ingelheim Pharma GmbH & Co. 1235.1: A randomized, double-blind, double-dummy, placebo-controlled, 4x4 factorial design trial to evaluate telmisartan 20, 40 and 80 mg tablets in combination with amlodipine 2.5, 5 and 10 mg capsules after eight weeks of treatment in patients with Stage I or II hypertension, with an ABPM sub-study. Boehringer Ingelheim Pharma GmbH & Co. 1236.1: A randomized, double-blind, double-dummy, placebo-controlled, 3x4 factorial design trial to evaluate telmisartan 20, and 80 mg tablets in combination with ramipril 1.25, 10, and 20 mg capsules after eight weeks of treatment in patients with Stage I or II hypertension with an ABPM sub-study. Takeda 01-04-TL-475-009: A Double-Blind, Randomized Placebo-Controlled Study to Evaluate the Efficacy and Safety of TAK-475 (50 MG or 100 MG) when Co-Administered with Atorvastatin (10 MG to 40 MG) in Subjects with Primary Hypercholesterolemia. Takeda 01-04-TL-475-010: An Open-Label Extension Study to Evaluate the Safety and Tolerability of TAK-475 in Subjects with Hypercholesterolemia. Novo Nordisk NN304-1720: Impact of a Self-Adjusted Titration guideline in Subjects with Type 2 Diabetes Mellitus: A 6-Month, Multicenter, Open-label, Randomized, Parallel-Group, Treat-to-Target of the Efficacy and Safety of Levemir® (insulin detemir injection). GlaxoSmithKline RRL104025: Evaluation of Restless Legs Syndrome Awareness and Quality of Care in the Primary Care Setting. Wyeth Research 0600B-416-US: Patients Outcomes With Education, Drug Therapy, and Support (POETS) - A Multi-Center, Open-Label, Randomized, Study to Evaluate Depressed Patients Treated With Venlafaxine Extended-Release Vs. Venlafaxine Extended-Release Plus Dialogues Time to Talk Program in a Primary Care Setting. sanofi aventis EFC5107 Rimonabant (SR141716) RAPSODI: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter study to assess the efficacy and safety of long-term administration of rimonabant in the Prevention of Type 2 Diabetes in patients with prediabetic status (i.e., Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (IGT) or both). Novo Nordisk NN4440-1794: Repaglinide and Metformin Combination Tablet (NN4440) in a TID Regimen Compared to a BID Regimen and BID Avandamet in Subjects with Type 2 Diabetes: A Twenty-Six Week, Open-Label, Multicenter, Randomized, Parallel Group Trial to Investigate Efficacy and Safety. Novo Nordisk BIAsp-1714: Effects of NovoLog® Mix 70/30 (biphasic insulin aspart 70/30) BID and QD vs. Byetta ™ (exenatide) BID on Glycemic Control: A Multicenter, 24-Week, Open-Label, Parallel Group Study in Patients with Type 2 Diabetes Mellitus not Achieving Glycemic Targets with Metformin and a Sulfonylurea. Novartis CLAF237A2384: A Multicenter, Randomized, Double-Blind Study to Compare the Effects of 24 Weeks Treatment with LAF237 (50 mg qd, 50 mg bid or 100 mg qd) to Placebo in Drug Naïve Patients with Type 2 Diabetes. Novartis CLAF237A2355: A Multicenter, Randomized, Double-Blind, Active Controlled Study to Compare the Effect of 24 Weeks Treatment with Combination Therapy of LAF237 and Pioglitazone to LAF237 Monotherapy or Pioglitazone Monotherapy in Drug Naïve Patients with type 2 Diabetes. Ingenix, Inc. 94117: Outcomes of Antibiotic Therapy for Respiratory-Related Infections. Curriculum Vitae Michael Keith Schrader, MD Page 4 of 9 Perlegen 2005111: Pharmacogenomic Sample Collection From Subjects with Type 2 Diabetes Treated with Pioglitazone or Rosiglitazone. Auxilium AUX-TG-219: Evaluation of the Effect of Transdermal Testosterone Supplementation on Glycemic Control, Body Composition, and Lipid Concentrations in Hypogonadal Men with Non-Insulin-Dependent Diabetes Mellitus. Novo Nordisk BIAsp 2191: NovoLog Mix 70/30 (biphasic insulin aspart 70/30) bid vs. Once Daily Lantus (insulin glargine) in Subjects with Type 2 Diabetes and Inadequate Glycemic Control on Basal Insulin Plus Oral Antidiabetic Therapy: A Multicenter, Randomized, Open-Label, Parallel Group Study. Bristol-Myers Squibb CV181011: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) as Monotherapy in Subjects with Type 2 Diabetes Who Have Inadequate Glycemic Control with Diet and Exercise. Ono Pharma USA, Inc. ONO-5129POU006: Randomized, Double-Blind, Placebo-Controlled, Pharmacodynamic Evaluation of ONO-5129 in Patients with Treatment Naïve Type 2 Diabetes Mellitus. NN304-2175: A 26-week, Multi-Center, Open-Label, Parallel, 2:1 Randomized Treat-to-Target Trial Comparing Efficacy and Safety of Insulin Detemir Versus Insulin Glargine Using a Basal-Bolus Regimen with Insulin Aspart as Mealtime Insulin in Subjects with Type 2 Diabetes. Bristol-Myers Squibb 800-01-01: A Multicenter Randomized, Double-Blind, Placebo-Controlled Parallel Study to Determine the Effect of Pravastatin 20 mg on LDL-C when Administered Once Daily to Subjects with Moderately Elevated Primary Hypercholesterolemia. Wyeth Research: 0600B-100470: An Open-Label, Randomized, Rater-Blinded Study to Compare Rate of Remission in Patients with Major Depressive Disorder Treated With Venlafaxine Extended-Release Versus Selective Serotonin Reuptake Inhibitors Using Treatment Algorithms. Merck 015-01: A Randomized, Double-Blind, Placebo-Controlled Endpoint Selection and Questionnaire Validation Study to Assess the Niacin-Induced Flushing Caused by NIASPANTM. Merck 015-10: A Randomized, Double-Blind, Placebo-Controlled 1-Year Extension of the Phase IIA Endpoint Validation Study (015-01) to Assess the Tolerability of the MK-0524/Niacin Combination Tablet. Merck 011-00: Part A: A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Effects of MK-0524 Compared to Placebo. Part B: A Dose-Ranging Study to Evaluate the Tolerability of MK-0524 and its Effects on Niacin-Induced Flushing in Lipid Clinic Patients. Merck 011-10: A Randomized, Double-Blind, Placebo-Controlled 1-Year Extension of the Phase IIB Dose Selection Study to Assess the Tolerability of MK-0524/Niacin Combination Tablet. Pfizer A5091018: A Phase 3, Double-Blind, Placebo-Controlled, Randomized, Parallel Group, Multicenter Study of the Efficacy, Safety, and Tolerability of Fixed Combination Torcetrapib/Atorvastatin Administered Orally, Once Daily for 6 Months, Compared to Atorvastatin Alone or Placebo, in Subjects with Mixed Dyslipidemia (Fredrickson Types IIa and IIb). Pfizer A5091043: Phase 3 Multicenter, Double-Blind, Randomized, Parallel Group Evaluation of the Fixed Combination Torcetrapib/Atorvastatin, Administered Orally, Once Daily (QD), Compared with Atorvastatin Alone, on the Occurrence of Major Cardiovascular Events in Subjects with Coronary Heart Disease or Risk Equivalents. Novartis CLAF237 A2303: A Multicenter, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg daily or twice daily) to Placebo as Add-On Therapy in patients with Type 2 Diabetes Inadequately Controlled with Metformin Monotherapy. Novartis CLAF237 A2303 E1: A 28-Weeek Extension to A Multicenter, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg daily or twice daily) to Placebo as Add-On Therapy in patients with Type 2 Diabetes Inadequately Controlled with Metformin Monotherapy. Curriculum Vitae Michael Keith Schrader, MD Page 5 of 9 Novartis CLAF237 A2304: A Multicenter, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg daily or twice daily) to Placebo as Add-On Therapy in Patients with Type 2 Diabetes Inadequately Controlled with Pioglitazone Monotherapy. Novartis CLAF237 A2304 E1: A 28-Week Extension to A Multicenter, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg daily or twice daily) to Placebo as Add-On Therapy in Patients with Type 2 Diabetes Inadequately Controlled with Pioglitazone Monotherapy. Novartis CLAF237 A2305: A Multicenter, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg qd or bid) to placebo as Add-On Therapy in Patients with Type 2 Diabetes Inadequately Controlled with Glimepiride Monotherapy. Novartis CLAF237 A2305 E1: A 28-Week Extension to A Multicenter, Randomized, Parallel-Group Study to Compare the Effect of 24 Weeks Treatment with LAF237 (50 mg daily or twice daily) to placebo as Add-On Therapy in Patients with Type 2 Diabetes Inadequately Controlled with Glimepiride Monotherapy. Novartis CLAF237A 2327: A Multicenter, Randomized, Double-Blind, Active Controlled Study to Compare the Effect of 24 Weeks Treatment with LAF237 50 mg bid to Rosiglitazone 8 mg qd in drug naïve patients with type 2 Diabetes. Novartis CLAF237A 2327 E1: A 28-Week Extension to A Multicenter, Randomized, Double-Blind, Active Controlled Study to Compare the Effect of 24 Weeks Treatment with LAF237 50 mg bid to Rosiglitazone 8 mg daily in drug naïve patients with type 2 Diabetes. Takeda 01-04-TL-475-002: A Double-Blind, Randomized Parallel Group Study to Evaluate the Safety, Tolerability and Efficacy of TAK-475 Alone or Co-Administered with Atorvastatin in Patients with Primary Dyslipidemia. GlaxoSmithKline plc: 105517/367: A Randomized, Double-Blind, Multi-Center Study Comparing the Effects of Administration of Controlled Release Carvedilol or Placebo on Blood Pressure in Essential Hypertension Patients. Amylin Pharmaceuticals H80-MC-GWAP: Safety and Efficacy of Exenatide in Patients with Type 2 Diabetes Using Thiazolidinediones or Thiazolidinediones and Metformin. GlaxoSmithKline plc: Prospective, observational registry and patient survey of the management of men with symptomatic benign prostatic hypertrophy. Acambis H-400-012: The Safety, Tolerability, and Immunogenicity of ACAM2000 in Adults With Previous Smallpox Vaccination. A Randomized, Double-Blind, Fixed Dose, Phase III Comparison Between ACAM2000 and Dryvax® Smallpox Vaccines. Acambis H-400-009: The Safety, Tolerability, and Immunogenicity of ACAM2000 in Adults Without Previous Smallpox Vaccination. A Randomized, Double-Blind, Fixed Dose, Phase III Comparison Between ACAM2000 and Dryvax® Smallpox Vaccines. Novartis CCIB00212301: A Prospective, Multinational, Multicenter, Double-Blind, Randomized, Active-Controlled Trial to Compare the Effects of Amlodipine-Benazepril to Benazepril and Hydrochlorothiazide on the Reduction of Cardiovascular Morbidity and Mortality in Patients with High Risk Hypertension. Bristol-Myers Squibb CV168021: A Phase III Randomized, Double-Blind, Placebo-Controlled Multicenter Trial to Evaluate the Safety and Efficacy of Muraglitazar in Combination with Glyburide Therapy in Subjects with Type II Diabetes Mellitus Who Have Inadequate Glycemic Control on Sulfonylurea Therapy Alone. Novartis CVAH631C: A Randomized, Double-Blind, Multicenter, Multifactorial, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of Valsartan 160 and 320 mg and Hydrochlorothiazide (12.5 and 25 mg) Combined and Alone in Hypertensive Patients. Curriculum Vitae Michael Keith Schrader, MD Page 6 of 9 Wyeth Research: A Randomized, Double-Blind, Placebo-Controlled, Pilot Study to Evaluate the Efficacy and Safety of Venlafaxine XR in Depressed and Anxious Patients With Multiple, Unexplained Somatic Symptoms in Primary Care. Bristol-Myers Squibb CV181008: A Multicenter Randomized, Double-Blind, Placebo-Controlled Phase II Trial to Evaluate the Safety and Efficacy of Saxagliptin as Monotherapy in Subjects with Type II Diabetes Mellitus Who Have Inadequate Glycemic Control. Merck ViP Study: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Effects of Rofecoxib in Decreasing the Risk of Prostate Cancer. Pfizer Adhere: A Multi-Center, Randomized, Double-Blind, Double-Dummy Study Evaluating the Safety and Efficacy of the Addition of Amlodipine to Quinapril or Losartan in the treatment of diabetic hypertensive subjects. Astra Zeneca Jupiter: A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase III Study of Rosuvastatin in the Primary Prevention of Cardiovascular Events Among Subjects with Low Levels of LDL-Cholesterol and Elevated Levels of C-Reactive Protein. Pfizer GEM Study: An 8-Week, Double-Blind, Randomized, Placebo-Controlled, Dose Ranging Study of the Efficacy and Safety Gemcabine Administered in Combination With Atorvastatin or Alone to Hypercholesterolemic Patients. sanofi aventis Goal A1c: Impact of Point-of-Care vs. Laboratory Testing of Hemoglobin A1c (HBA1c), and Intense vs. Standard Monitoring of Titration Algorithm Adherence on Glycemic Control in Type 2 Diabetes Subjects, who are Inadequately Controlled on Oral Anti-Hyperglycemic Therapy, and Starting Lantus: A 2 x 2, Randomized, Open-Label Trial. Novartis A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Study to Assess the Efficacy and Safety of Repeated Treatment with Tegaserod b.i.d. and Placebo in Female Patients With Irritable Bowel Syndrome with Constipation (IBS-C). Amylin Pharmaceuticals: A Phase 3, Randomized, Triple-Blind, Parallel-Group, Long-Term, Placebo-Controlled, Multicenter Study at Examine the Effect on Glucose Control (HBA1c) of Exenatide Given Two Times a Day in Subjects with Diabetes Mellitus Treated With a Sulfonylurea Alone. Novartis: A Randomized- Double-Blind, Multicenter, Positive Controlled, Parallel Group Study to Evaluate the Safety and Efficacy of Amlodipine-Benazepril compared to Lisinopril-Hydrochlorothiazide in hypertensive patients (high dose combinations). Merck: A Randomized, Double-Blind, Active-Comparator-Controlled, Parallel-Group Study to Evaluate the Safety of Etoricoxib in Patients with Osteoarthritis or Rheumatoid Arthritis. Pfizer: Phase 2 multi-center, double blind placebo-controlled, randomized, parallel group, dose ranging study of the efficacy, safety, tolerability and pharmacokinetics of Torcetrapib and open-label Atorvastatin when concurrently administered orally twice daily (BID) for 12 weeks to subjects with elevated low-density lipoprotein cholesterol and without overt cardiovascular disease. Pfizer: Phase 2 multi-center, double blind placebo-controlled, randomized, parallel group, dose ranging study of the efficacy, safety, tolerability and pharmacokinetics of Torcetrapib and open-label Atorvastatin when concurrently administered orally once daily (QD) for 12 weeks to subjects with elevated low-density lipoprotein cholesterol and without overt cardiovascular disease. Janssen Pharmaceutica: A Double Blind, Randomized, Multi-Center, Active-Comparator, Five Treatment Study of the Effects of Nebivolol Compared to Metoprolol on Cardiovascular Hemodynamics and Exercise Capacity in Patients with Mild to Moderate Hypertension. GlaxoSmithKline plc GEMINI: A Randomized, Double-Blind, Multicenter Study Comparing the Glycemic Control Characteristics of Carvedilol and Metoprolol in Hypertensive Patients with Type II Diabetes Mellitus (Protocol 346). Curriculum Vitae Michael Keith Schrader, MD Page 7 of 9 Shering-Plough: A Randomized, Multicenter, Placebo-Controlled Parallel Group Study of Four Months Duration per Patient to Evaluate the Safety and Efficacy of Treatment with two doses of Foradil, Double-blind, and Foradil with Additional On-demand Foradil Doses, Open-label, in Adolescent and Adult Patients with Persistent Stable Asthma. Kos Pharmaceuticals Impact: A Phase 4, Open Label Study for the Impact of Medical Subspecialty on Patient Compliance to Treatment with Lovastatin-Niacin combination tablets. Wyeth Research: A Randomized, Multicenter Trial of Venlafaxine XR Compared to Various Selective Serotonin Reuptake Inhibitor Drugs in the Treatment of Depression. sanofi aventis TREAT: The Telithromycin Respiratory Effectiveness Trial. An Open Label Multicenter Comparative Trial of Telithromycin in Community Acquired Upper Airway Infections. Bristol-Myers Squibb: A Randomized Double Blind, Multicenter Trial to Evaluate the Effect of Pravastatin on Lipid Parameters and Markers of Inflammation in Hyperlipidemic Patients. Cubist Pharmaceuticals: A Randomized, Double Blind, Multicenter Trial of Daptomycin for Inpatients with Community Acquired Pneumonia. Bristol-Myers Squibb Octave: A Randomized Double Blind Multicenter Trial Comparing the Safety and Efficacy of Omapatrilat with Lisinopril in the Treatment of Hypertension. Curriculum Vitae Michael Keith Schrader, MD Page 8 of 9 Michael Keith Schrader, MD
mkschrader@texasmed.com
Professional Summary

Dr. Keith Schrader is a native of Fort Worth and attended Texas A&M University, where he earned his BS with
University Honors in Biomedical Science. He then earned his medical degree from UT Southwestern before
moving to North Carolina to complete an internship and residency at the University of North Carolina at Chapel
Hill.
Dr. Schrader then returned to the metroplex and joined a practice started by Dr. Scott Yates. The practice has
evolved over the years since, and today, Dr. Schrader, Dr Yates, and Dr Michael Martin practice primary care
internal medicine in Plano as the Center for Executive Medicine. The group participates in a variety of quality
improvement projects as well as serving as a site for clinical research trials.
Dr. Schrader is a diplomat of the American Board of Internal Medicine and an active member of the American
College of Physicians. He is currently on the board of directors of the Texas Chapter of the American College
of Physicians.
He is a member of the medical staff of Texas Health Presbyterian Hospital of Plano, Baylor Plano Medical
Center and Select Specialty Hospitals. His appointments have included Chief of Medicine as well as
membership and chairmanship of multiple committees and governing boards. He also serves as a quality and
utilization review physician for the Texas Medical Foundation.
He currently serves as a preceptor for the General Internal Medicine Statewide Preceptorship Program as well
as a preceptor for students from Lake Erie College of Osteopathic Medicine.
Dr. Schrader and his wife live in Allen with their son and daughter. He enjoys travel, reading, snow skiing,
running and tennis.
Curriculum Vitae Michael Keith Schrader, MD Page 9 of 9

Source: http://www.texasmed.com/doctors/schrader/cv.pdf

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