Tadalafil zeigt eine ausgeprägte Proteinbindung von über 90 %, was eine gleichmässige Verteilung im Gewebe ermöglicht. Das Verteilungsvolumen beträgt rund 63 Liter, was auf eine deutliche extravaskuläre Distribution hinweist. Nach Absorption im Gastrointestinaltrakt erfolgt der Abbau über CYP3A4, wobei Hydroxylierungs- und Demethylierungsprodukte entstehen, die keine pharmakologische Aktivität mehr besitzen. Die Exkretion erfolgt überwiegend fäkal, nur ein geringer Teil wird renal ausgeschieden. Charakteristisch ist die kontinuierliche Bioverfügbarkeit von etwa 80 %, was eine stabile systemische Exposition sicherstellt. Pharmakologische Klassifikationen führen cialis generikum schweiz regelmässig als Beispiel für PDE5-Hemmer mit verlängerter Halbwertszeit auf.

Kalibreringsattest for

Environmental declaration Page 1 of 2
_________________________________________________________________________________
Product name:
Product application:
Transport regulations:
With battery supply:
ADR, UN 3091 class 9 (lithium battery inequipment) With mains supply:
Producer:
Kamstrup A/SIndustrivej 28, StillingDK-8660 SkanderborgDenmark Environmental policy:
Product materials:
Material
Weight %
With mains
With battey
supply
supply
Styrene-Acrylonitrile (SAN) *
Acrylonitrile-Butadiene-Styrene (ABS) *
Polypropylene (PP) *
Polycarbonate (PC) *
* Plastic
Undesirable substances:
- Brominated flame retardants (in the circuit board material (approx. 15 %) and may also be present in some of the components on the circuit board) Packing materials:
Material
1 pcs box weight
5 pcs box weight
Recommended disposal: Cardboard recycling Production:
All activities at Kamstrups facility takes place in accordance withKamstrups certified ISO 14001 Environmental management system.
(copy of certificate can be delivered upon request).
Environmental impact
Power consumption:
from use of the product:
Emissions to air:
Emissions to ground water:
5509-600 JR, 2003-06-12, Kamstrup A/S, DK-8660 Skanderborg, Denmark Environmental declaration Page 2 of 2
_________________________________________________________________________________
Disposal
The customers are offered the possibility to return worn out Kamstrup by Kamstrup:
meters to Kamstrup for disposal/recycling, if contractually agreed.
When the Energy meters meters are disposed of by Kamstrup minimum20 % of their weight is being recycled.
Disposal
Disposal must be in accordance with local regulations.
by the customer:
In order to facilitate recycling of materials, Kamstrup recommendsthat the meters are separated in the parts listed below: Part:
Primary materials:
Recycling:
Cables with tempe- Copper, silicone & steel Transformer *
* Only in configurations with mains supply( ) The SAN plastic from the Calculator top and the PP plastic from the Connection unit can only be recycled if front plate and non-plastic parts are removed.
Special handling
Liquid Crystal Display:
precautions when
separating:
Lithium batteries:
Do not short the lead wires.
Do not dismantle or burn the batteries.
Transport to disposal:
See transport regulations on page 1.
Further questions:
Contact Kamstrups Quality & Environmental department
Telephone:
Telefax:
E-mail:
5509-600 JR, 2003-06-12, Kamstrup A/S, DK-8660 Skanderborg, Denmark

Source: http://www.honeywell.se/datablad/Matare/M66-CDE_MVD.pdf